Clinical trials: Nosocomial Infections
Nosocomial Infections
Study of Talactoferrin Oral Solution for Nosocomial Infection in Preterm Infants
This study will evaluate the safety, toxicity and efficacy of talactoferrin in reducing the incidence of all nosocomial infections in prematurely-born infants.
- Trial name
- NCT00854633
- Testing
- Talactoferrin
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Agennix
Nosocomial Infection
New Dosages of Inflammatory Markers for the Early Diagnosis of Nosocomial Bacterial Infections of the Newborn
This study aims to evaluate new dosage of inflammatory markers or new inflammatory markers for the diagnosis of nosocomial bacterial infection.
- Trial name
- NOSODIAG (NCT00701948)
- Where
- 2 sites in France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Strasbourg, France
Death, Nosocomial Infection
Prophylactic Probiotics in Premature Infants
This study tries to determine whether the oral administration of a specific probiotic (good bacteria) in premature infants hospitalized in a neonatal intensive care unit may prevent infections and the development of a severe…
- Trial name
- C3P (NCT00727363)
- Testing
- Lactobacillus reuteri
- Where
- 8 sites in Colombia
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- Colombian Neonatal Research Network
Nosocomial Infection, Bacteremia
Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections
Patients in the intensive care unit are at risk for many infections because the severity of illness and the procedures necessary to care for them.
- Conditions
- Nosocomial Infection, Bacteremia, Sepsis, Pneumonia
- Trial name
- NCT00130221
- Testing
- 2% chlorhexidine gluconate impregnated cloth, Daily bathing with Bar soap
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Cook County Health
Infection in ICU
Antibiotic Therapy for Hospital-Acquired Infections in ICU Patients
Antibiotic Therapy for Hospital-Acquired Infections in ICU Patients. A prospective, observational, multicenter study (ANTHICUS).
- Trial name
- ANTHICUS (NCT00543894)
- Volunteers
- 500 people
- Sponsor
- AstraZeneca
Hospital Acquired Infection
Investigation on the Dynamic Changes in Air Microbiome in Intensive Care Unit
The microbiome of ICU, especially the air microbiome of ICU is not clear. The relationship between the microbiome of ICU and the hospital- acquired infection needs to be clarified.
- Trial name
- NCT04954300
- Testing
- no intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking University Third Hospital
Nosocomial Infection
Administration of a Lactobacillus GG and Vitamins Containing Mixture is Effective in Preventing Nosocomial Infection in Children
Nosocomial infections are infections that occur from the time of 'entry in the hospital up to 48h after discharge. In most developed countries, the incidence of nosocomial infections in children is between 5% and 44% with the…
- Trial name
- NCT02558192
- Testing
- Lactobacillus Rhamnosus GG
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Federico II University
Ventilator Associated Pneumonia, Nosocomial Infections in Children
Decreasing Antibiotic Use in Infants With Suspected Ventilator-associated Infection
This is a prospective study with three specific aims: (1) To convene a consensus conference to develop a guideline for antibiotic use in infants (age < 3 yrs) with suspected ventilator-associated infection; (2) To evaluate…
- Conditions
- Ventilator Associated Pneumonia, Nosocomial Infections in Children, Microbial Colonization
- Trial name
- VAIN2 (NCT03041207)
- Testing
- Development and implementation of an antibiotic guideline
- Where
- 23 sites in United States, Canada
- Volunteers
- 555 people
- Sponsor
- Virginia Commonwealth University
Nosocomial Infection
In Vitro Activity of Ceftolozane-tazobactam Against Contemporary Nosocomial Gram "-" Pathogens Isolated in Russia
Infections caused by resistant gram-negative bacteria are becoming increasingly prevalent and now constitute a serious threat to public health worldwide because they are difficult to treat and are associated with high morbidity…
- Trial name
- NCT04679610
- Where
- Russia
- Volunteers
- 700 people
- Sponsor
- The Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (IACMAC)
Infections, Nosocomial, Infections, Respiratory Tract
Antibacterial Effect of Zinc Oxide Nanoparticles on Acinetobacter Baumannii Isolated From Patients With Hospital Acquired Infections in Sohag University Hospitals, Egypt
A. baumannii is known as the most frequently isolated organism in intensive care units (ICUs), causing a variety of nosocomial infections, including pneumonia, urinary tract infections (UTIs), bacteremia as well as skin and soft…
- Trial name
- NCT06628076
- Testing
- Culture specific antibiotic therapy, Antibiotic, Biofilm assessment
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Neonatal Sepsis
Chlorhexidine Gluconate and Alcohol Hand Rubbing on Healthcare-associated Infection
This study aims to compare of effect of chlorhexidine gluconate and alcohol hand rubbing on healthcare-associated infection (HCAI) in neonatal intensive care unit at Alexandria University Children Hospital.
- Trial name
- NCT07421323
- Testing
- Alcohol hand rub group, Chlorhexidine hand rub
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Hospital Infection
Application of Standardized Cleaning and Disinfection Mode of HFT Surface in Hospital Infection Prevention and Control
The scientific, feasible and effective mode of standardized cleaning and disinfection of ICU high-frequency contact surfaces is discussed and verified.
- Trial name
- NCT04920240
- Testing
- cleaning and disinfection mode for surfaces with high frequency contact, Routine procedure
- Where
- China
- Volunteers
- 432 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Nosocomial Pneumonia
Safety and Pharmacokinetics of Ceftolozane/Tazobactam in Pediatric Participants With Nosocomial Pneumonia (MK-7625A-036)
This is a phase 1, open-label, non-comparative, multicenter clinical study to evaluate the safety, tolerability, and pharmacokinetics of ceftolozane/tazobactam (MK-7625A) in pediatric participants with nosocomial pneumonia (NP).
- Trial name
- NCT04223752
- Testing
- Ceftolozane/Tazobactam
- Where
- 24 sites in United States, Chile and 7 more
- Volunteers
- 41 people
- Sponsor
- Merck Sharp & Dohme LLC
Nosocomial Infections, Sepsis
Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants
The purpose of this study is to show whether Veronate, a donor-selected staphylococcal human immune globulin intravenous (IGIV), can prevent an infection in the blood caused by staphylococcal bacteria in premature babies weighing…
- Conditions
- Nosocomial Infections, Sepsis, Staphylococcal Infections, Candidemia
- Trial name
- NCT00113191
- Testing
- Veronate
- Where
- 93 sites in United States, Canada
- Volunteers
- 2,000 people
- Sponsor
- Bristol-Myers Squibb
Nosocomial Infection, Infection Control
Can Environmental Cleanliness be Assessed by BCA (Bicinchoninic Acid) Method
Effective cleaning of surfaces in the hospital environment is an absolute necessity to reduce pathogen transmission. Multi Drug Resistant Organisms (MDRO) in ICU are among the leading causes of hospital-acquired infections.
- Conditions
- Nosocomial Infection, Infection Control, Multi-antibiotic Resistance
- Trial name
- BCA (NCT04212130)
- Testing
- BCA method for assessing environmental cleanliness
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
Nosocomial Infections
Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality
This 4-year cluster randomized controlled trial aims to determine whether implementation of Evidence-based Practice for Improving Quality (EPIQ) method can reduce hospital-acquired infection in Chinese Neonatal Intensive Care…
- Trial name
- NCT02600195
- Testing
- Evidence-based Practice for Improving Quality (EPIQ) method
- Where
- 24 sites in China
- Volunteers
- 15,600 people
- Sponsor
- Children's Hospital of Fudan University
Healthcare Associated Infection
Monitors to Improve Indoor Carbon Dioxide (CO2) Concentrations in the Hospital
Ventilation with fresh outdoor air has recently gained considerable attention as a means to reduce the potential risk of indoor aerosol transmission of respiratory pathogens such as severe acute respiratory syndrome coronavirus 2…
- Trial name
- MICH (NCT04770597)
- Testing
- Aranet4 Home CO2 monitor
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Imelda Hospital, Bonheiden
Nosocomial Infection, Necrotizing Enterocolitis
Effect of Oral Probiotic Supplementation on The Rate of Hospital Acquired Infection and Necrotizing Enterocolitis in Preterm Very Low Birth Weight Infants
The purpose of this study is to determine whether oral probiotic supplementation could reduce the incidence of nosocomial infections in preterm infants.
- Trial name
- NCT01340469
- Testing
- probiotics
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Ventilator Associated Pneumonia, Nosocomial Pneumonia
Oral Hygiene With Chlorhexidine and Incidence of Ventilator-Associated Pneumonia in Children Submitted to Heart Surgery
Hospital infections play an important role in the increase of patients' morbimortality and hospitalization costs, especially in the case of individuals admitted to intensive care units (ICU) during postoperative heart surgery.
- Conditions
- Ventilator Associated Pneumonia, Nosocomial Pneumonia, Heart Surgery
- Trial name
- NCT00829842
- Testing
- oral hygiene
- Volunteers
- 160 people
- Sponsor
- University of Sao Paulo
Leeches, Healthcare Associated Infection
Risk Benefit Ratio of Hirudotherapy: Retrospective Single-center Study of 37 Cases Over a Period of 9 Years
Venous congestion in transplanted or re-implanted tissues remains a common and chal-lenging complication in plastic and reconstructive surgery.
- Trial name
- AMLEE (NCT04676581)
- Testing
- Leech Therapy
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens