Clinical trials: Nulliparous
Management of the Second Stage of Labor in Obese Nulliparous Women by Either Passive Descent or Immediate Pushing.
Passive Descent in Obese Nulliparous Gravidae
Obesity rates in reproductive aged women in the United States are rising. It is now universally accepted that obesity is associated with many adverse pregnancy outcomes and post-operative complications following cesarean section.
- Trial name
- NCT02080429
- Testing
- Passive Descent, Pushing
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Preterm Delivery, Cervical Length
RCT of Progesterone to Prevent Preterm Birth in Nulliparous Women With a Short Cervix
The purpose of this study is to see if giving progesterone medication to pregnant women, who have never delivered a baby after 19 weeks of pregnancy and who have a short cervix, lowers the risk of early delivery and improves the…
- Trial name
- SCAN (NCT00439374)
- Testing
- 17 alpha-hydroxyprogesterone caproate
- Where
- 14 sites in United States
- Volunteers
- 657 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Neurodevelopmental Disorders
5-Year Follow-up of Children and Mother After Expectant Management Versus Induction of Labor in Low-risk Nulliparous Women at 39 Weeks of Gestation
In France, the rate of labor induction has markedly increased in recent years, partly following the ARRIVE trial suggesting short-term benefits of elective induction at 39 weeks in low-risk nulliparous women.
- Trial name
- FAMILY-FA (NCT07330336)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 4,200 people
- Sponsor
- University Hospital, Bordeaux
Perineal Lacerations
A Trial of Bed Versus Stirrups Delivery in Nulliparous Women for Prevention of Perineal Lacerations
The investigators hypothesize that the rate of perineal lacerations in nulliparous women will be reduced by a simple change in common obstetrical delivery practice, i.e., bed delivery versus conventional delivery in obstetrical…
- Trial name
- NCT00895973
- Testing
- Stirrups delivery vs bed delivery
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Contraception
Comparative Efficacy of Lidocaine Spray Versus Vaginal Misoprostol in IUD Insertion
the aim of the present study is to compare the safety and efficacy of lidocaine spray versus misoprostol in reducing pain during IUD insertion in adolescents and nulliparous women
- Trial name
- NCT04339049
- Testing
- lidocaine spray, vaginal misoprostol
- Where
- Egypt
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Cairo University
Prolonged Labor
Prediction of Delivery Mode by Ultrasound-assessed Fetal Position in Nulliparous Women With Prolonged First Stage of Labor.
In the past years, numerous studies have been published on the use of ultrasound during labor, showing this is an effective, accurate and objective tool for the assessment of the fetal head position and station.
- Trial name
- NCT05206409
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Nulliparous Women Who Scheduled for Labor Induction
Concurrent Membrane Sweeping With Dinoprostone Versus Dinoprostone in Labor Induction of Nulliparas at Term With an Unfavorable Cervix
To compare concurrent membrane sweeping with dinoprostone versus dinoprostone in labor induction for nulliparas at term with an unfavorable cervix
- Trial name
- NCT01792375
- Testing
- Concurrent membrane sweeping with Dinoprostone, 10mg Dinoprostone vaginal insert
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Seoul National University Hospital
Pain
Self-administered Intravaginal 2% Lidocaine Gel Prior to Intrauterine Device Insertion in Nulliparous Women
This study is designed to evaluate if self-inserted intravaginal 2% lidocaine gel is effective at decreasing pain during intrauterine device insertion in nulliparous women.
- Trial name
- LIVIIN (NCT01534520)
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pregnancy Related
Elective Induction of Labour at Thirty Nine Weeks: a Prospective Observational Study
Adverse events are considered to increase in pregnancies extending beyond 39 weeks. For multiparous patients, especially those with a favourable cervix, it is perhaps easy to justify an elective induction at 39 weeks given the…
- Trial name
- EIOL39 (NCT04597528)
- Testing
- Elective Induction
- Where
- India
- Volunteers
- 315 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Postpartum Disorder
Bladder Displacement During Abdominal and Pelvic Floor Exercises
This study evaluates the bladder base displacements during abdominal and pelvic floor exercises in postpartum women comparing to nulliparous women
- Trial name
- NCT04154527
- Testing
- Pelvic Floor and Abdominal Exercises
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- University of Castilla-La Mancha
Pain
Massage for Pain Relief During the Active Phase of Labor
The objective of this research is to evaluate the effect of massage therapy as a resource for pain relief during the active phase of labor.
- Trial name
- NCT01392053
- Testing
- Lumbosacral Massage
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pre-eclampsia, Intra-uterine Growth Restriction
Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers
The objective of this study is to test the efficacy of low-dose aspirin (160 mg/day), given bedtime and started early during pregnancy (≤ 15 +6 weeks of gestation) in nulliparous pregnant women selected as "high-risk" by the…
- Trial name
- PERASTUN (NCT01729468)
- Testing
- Aspirin
- Where
- 17 sites in France, Martinique
- Volunteers
- 1,106 people
- Sponsor
- University Hospital, Tours
Contraception
Comparative Safety and Efficacy of Vaginal Dinoprostone Versus Lidocaine-prilocaine Cream in Copper IUD Insertion
the aim of the present study is to Compare Safety and Efficacy of Vaginal dinoprostone Versus Lidocaine-prilocaine Cream in copper IUD Insertion in nulliparous women: a randomized controlled trial
- Trial name
- NCT04340778
- Testing
- vaginal dinoprostone, Lidocaine-prilocaine Cream
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labor
Hyoscine Butylbromide Effect on Duration of Labor
To evaluate the duration of labour (active phase of labour) in nulliparous women with gestations between 37 and 41 6/7 weeks when 20 mg of Hyoscine butylbromide was applied intravenously and compared with similar patients that…
- Trial name
- NCT03441217
- Testing
- Hyoscine Butylbromide 20Mg/1mL Injection, Saline Solution
- Where
- Panama
- Volunteers
- 218 people
- Sponsor
- Saint Thomas Hospital, Panama
Cervical Ripening
Misoprostol For Nulliparous Women Before Hysteroscopy
To compare the impact of 400-microgram self-administered vaginal versus self-administered oral misoprostol at home on preoperative cervical ripening in nulliparous women prior to outpatient hysteroscopy.
- Trial name
- NCT01156948
- Testing
- misoprostol, oral misoprostol
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
IUD Insertion Pain
the Effect of Isosorbide Mononitrate in Reducing Pain During Cooper Intrauterine Device Insertion
The aim of the study is to evaluate the efficacy of isosorbide mononitrate vaginal administration in reducing pain during copper IUD insertion in nulliparous women
- Trial name
- NCT04312048
- Testing
- Isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Cairo University
Pain
Misoprostol Prior to Intrauterine Device (IUD) Insertion in Nulliparous Women
The purpose of this study is to see if using misoprostol makes the intrauterine device insertion easier and less painful in women who have never had a baby.
- Trial name
- NCT01307111
- Testing
- Misoprostol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Pregnancy, Pregnancy Complications
Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be
Forty percent of pregnant women in the United States are women who have never given birth. As a group, they sometimes have complications with their pregnancy, but there is no information from a previous pregnancy to identify who…
- Trial name
- nuMoM2b (NCT01322529)
- Where
- 17 sites in United States
- Volunteers
- 10,038 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Nulliparous Women With Prolonged Latent Phase
Trial on Early Induction Versus Expectant Management of Nulliparous Women With a Prolonged Latent Phase
The purpose of the study was to compare early induction versus expectant management regarding outcome and experience of delivery in nulliparous women with a prolonged latent phase.
- Trial name
- NCT01863797
- Testing
- Early induction, Expectant mamagement
- Where
- Sweden
- Volunteers
- 138 people
- Sponsor
- Karolinska Institutet
Breech Presentation, Complication of Pregnancy
Intravenous (IV) Nitroglycerin for Versions in Nulliparous Women
Breech presentations (where a baby presents with feet or bottom down) have an increased risk of perinatal and neonatal complications, and are usually delivered by cesarean section.
- Trial name
- INVERT (01) (NCT00896311)
- Testing
- IV Nitroglycerin, Normal saline
- Where
- 3 sites in Canada
- Volunteers
- 82 people
- Sponsor
- University of Calgary