Clinical trials: Nutrition Disorders
Pediatric Obesity
Sweet Taste Responsiveness in Relation to Insulin, Leptin and Adiposity Among Obese Treatment Seeking Children
This study will explore whether a relationship exists between insulin and leptin resistance, sweet taste responsiveness, and adiposity.
- Trial name
- NCT04600648
- Testing
- Serum insulin level, Serum Leptin test
- Sponsor
- State University of New York at Buffalo
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity, Overweight
FutureShape Family
The number of adults and children living with obesity is increasing worldwide. Once childhood obesity has developed, more than 80% of children carry the obesity into adulthood, with a high risk of cardiometabolic disease, poor…
- Trial name
- NCT07872904
- Testing
- Family Care, Standard Care, Semaglutide (administered by PDS290 pen-injector)
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Signe Torekov
Pediatric Obesity, Inhibition
Brain Mechanisms of Overeating in Children
The proposed research will follow healthy weight children who vary by family risk for obesity to identify the neurobiological and appetitive traits that are implicated in overeating and weight gain during the critical…
- Conditions
- Pediatric Obesity, Inhibition, Decision Making, fMRI
- Trial name
- RO1 (NCT03341247)
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cholestasis, Prematurity
Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in Infants
Hypothesis to be Tested: Since the first description of intravenous alimentation over half a century ago, parenteral nutrition (PN) has become a common nutritional intervention for conditions characterized by inability to…
- Conditions
- Cholestasis, Prematurity, Gastroschisis, Intestinal Atresia
- Trial name
- NCT01062815
- Testing
- Parenteral Nutrition
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Miami
Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty
YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition
More children will survive to adulthood today than at any other point in human history, as evidenced by the proportion of live births and absolute numbers.
- Conditions
- Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty, Malnutrition, Child, Gestational Diabetes
- Trial name
- YUVAAN (NCT05603793)
- Testing
- Knowledge, Attitude & Practices
- Where
- India
- Volunteers
- 1,304 people, healthy volunteers welcome
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Childhood Obesity
A Three-year Behavioral Treatment of Obese Children
The prevalence of overweight and obesity among children and adolescents has reached epidemic proportions worldwide. Among Swedish 10-year old children 15-20% are overweight and 3-5% are obese.
- Trial name
- NCT01029964
- Testing
- Individually and in groups
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Karolinska University Hospital
Obesity, Metabolic Syndrome
Milk Components and Metabolic Syndrome
Milk contains a vast number of bioactive components that have been suggested to have a positive impact on human health, of special interest is the effects related to metabolic syndrome and obesity but the effect of the individual…
- Trial name
- MoMS (NCT00785499)
- Testing
- Milk Components and Metabolic syndrome
- Where
- Denmark
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
X-Linked Hypophosphatemia
Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH)
The primary objectives of this study are to: Assess the long-term safety of KRN23 subcutaneous (SC) administration in adult subjects with XLH Assess the proportion of subjects achieving serum phosphorus levels in the normal range…
- Trial name
- NCT02312687
- Testing
- KRN23
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- Kyowa Kirin, Inc.
Overweight, Obesity
Effects of Nutrition Meal Replacement and Individualized Exercise Prescription on Type 2 Diabetes
This study evaluates the nutritional meal replacement and individualized exercise prescription intervention on overweight and obese type 2 diabetes mellitus.
- Conditions
- Overweight, Obesity, Type2 Diabetes
- Trial name
- NCT02984605
- Testing
- nutritional meal replacement
- Volunteers
- 200 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Metabolic Syndrome X
OPUS School Meal Study
The aim of this randomized crossover study, is to investigate the effect of school meals based on a sustainable New Nordic Diet on growth, learning abilities, well-being, sleep quality, physical activity and risk markers of…
- Trial name
- NCT01457794
- Testing
- School meals based on the principles of the New Nordic Diet
- Where
- Denmark
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- Arne Astrup
Type 2 Diabetes, Obesity
Preventing Diabetes in Latino Families
Purpose: This study will test the efficacy of a family-focused lifestyle intervention for reducing type 2 diabetes (T2D) risk factors and increasing Quality of Life (QoL) among high-risk Latino families.
- Conditions
- Type 2 Diabetes, Obesity, Pediatric Obesity
- Trial name
- NCT05228522
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Pediatric Obesity
Childhood Obesity, Lifestyle Interventions and Weight Development
Childhood obesity has been associated with increased risk of both continued excess body weight, development of non-communicable lifestyle diseases and impaired mental health.
- Trial name
- NCT05345353
- Testing
- Fat For Fight (FFF), The Aarhus Protocol, The Children's Obesity Clinic Treatment (TCOCT), The Randers Protocol
- Where
- Denmark
- Volunteers
- 2,898 people
- Sponsor
- University of Aarhus
Obesity, Child
Frequency Needed for School-based Obesity Intervention
This randomized controlled trial compared changes in Mexican-American, adolescent standardized body mass index (zBMI) from a school-based obesity intervention given zero, one, three, or five days a week.
- Trial name
- NCT03797105
- Testing
- School-Based Obesity Intervention (FLOW)
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- University of Houston
Obesity
MPOWERed Messages: Tailored Mobile Messages to Enhance Weight Loss for Teens
Obesity affects millions of American children and increases their risk of adult obesity, a myriad of serious illnesses, increased healthcare costs, and premature death. It is vital to find ways to reverse this epidemic.
- Trial name
- NCT01448551
- Testing
- Tailored Mobile Messages to Enhance Weight Loss for Teens
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Genetic Disorder, Prader-Willi Syndrome
Retrospective Observational Study on Efficacy and Safety of Norditropin® in Children With Prader-Willi Syndrome
This study is conducted in Europe. The aim of this observational study is to collect data from children with Prader-Willi Syndrome, who have been treated off-label with Norditropin® for more than 12 months to seek approval for…
- Trial name
- NCT00705172
- Testing
- somatropin
- Where
- 3 sites in Denmark, Germany and 1 more
- Volunteers
- 41 people
- Sponsor
- Novo Nordisk A/S
Asthma, Vitamin D Deficiency
Vitamin D in Pediatric Asthma: a Randomized Controlled Open-label Pilot Trial
This is a pilot randomized controlled trial of lower vs. higher dose vitamin D supplementation in D-deficient asthmatic children, to determine necessary sample sizes for outcome measures in a larger multisite study, and to…
- Trial name
- D-Asthma (NCT02054975)
- Testing
- Vitamin D2 + vitamin D3, Vitamin D3
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Nationwide Children's Hospital
Obesity
Impact of Non-Commercialism Policy in Seattle Schools
This pilot study on the impact of a non-commercialism policy in Seattle schools will assess and evaluate obesity-related health outcomes of a real-life policy decision, recently voted on and adopted by the Seattle School Board.
- Trial name
- NCT00063700
- Testing
- reducing exposure to marketing pressures
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
The Bariatric Surgery Registry
Persons with obesity are more likely to suffer from many other serious health conditions and are more likely to die young. Lifestyle interventions have not been found to be an effective long-term solution for treating obesity.
- Trial name
- BSR (NCT03441451)
- Where
- Australia
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Monash University
Impaired Glucose Tolerance, Prediabetes
CGM and Lifestyle Changes in Patients With Impaired Glucose Tolerance
The incidence of type 2 diabetes (T2D) in children is increasing, paralleling the rising incidence of obesity. Preventing children and adolescents from developing T2D is critical.
- Trial name
- NCT05387551
- Testing
- CGM
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nemours Children's Clinic
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