Clinical trials: Nutritional Deficiencies
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Chronic Myeloproliferative Disorders, Leukemia
Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With Dapsone
RATIONALE: Gathering information about how often methemoglobinemia occurs in young patients receiving dapsone for hematologic cancer or aplastic anemia may help doctors learn more about the disease and plan the best treatment.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00993694
- Testing
- chemotherapy, dapsone, medical chart review
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Vanderbilt University
Congenital Heart Disease
Nitrogen Balance in Infants After Post Cardiothoracic Surgery
The objective is to the amount of protein infants require after cardiopulmonary bypass surgery.
- Trial name
- NCT01368705
- Testing
- Standard protein delivery, Intervention 1 (2.2g/kg/day), Intervention 2 (3.0 g/kg/day)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- The Hospital for Sick Children
Early Childhood Caries, Vitamin D Deficiency
Vitamin D Status With Early Childhood Caries
Studies that give people vitamin D supplements to prevent caries have found that vitamin D is effective at preventing the development of caries.
- Trial name
- NCT03521492
- Testing
- serum vitamin D , calcium , parathyroid hormone and albumin level
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
Malnutrition, Dwarf - Nutritional
Nutritional Status on Admission to Pediatric Intensive Care
Study rationale: Children admitted to intensive care are often chronically ill and the intensive care setting may upset the balance between nutritional intakes and needs.
- Trial name
- NUTRI-REAPED (NCT02293434)
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Montpellier
X-linked Hypophosphatemia (XLH)
Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age
A Phase 1/2, Open-label, Multicenter, Non-randomized Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Paediatric Patients from Birth to Less than 1 Year of Age with X-linked Hypophosphatemia…
- Trial name
- NCT04188964
- Testing
- Burosumab
- Where
- 9 sites in Austria, France and 4 more
- Volunteers
- 16 people
- Sponsor
- Kyowa Kirin Pharmaceutical Development Ltd
Vitamin D Deficiency
Utility of a Urine Screening Tool for Vitamin D Deficiency in Infants and Toddlers
Background: Vitamin D plays a key role in calcium absorption in the gut and in skeletal development. Vitamin D deficiency is common, affecting an estimated one billion people worldwide, including developed countries.
- Trial name
- NCT01105689
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Down Syndrome, Vitamin D Deficiency
Effect of Exercise Intensity on Vitamin D
Children with Down's syndrome (DS) are more liable to vitamin D deficiency. Treating this deficiency with supplements is associated with the risk of intoxication due to increased intestinal absorption or decreased vitamin D…
- Trial name
- NCT05024110
- Testing
- High intensity treamill exercise training., Moderate intensity treamill exercise training.
- Where
- Saudi Arabia
- Volunteers
- 44 people
- Sponsor
- Taif University
Vitamin D Deficiency, Stem Cell Transplant Complications
A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT
Research has suggested that children with sufficient vitamin D levels undergoing hematopoietic stem cell transplant (HSCT) have improved outcomes, including lower incidences of infection and graft-versus-host disease (GVHD), as…
- Conditions
- Vitamin D Deficiency, Stem Cell Transplant Complications, Pediatric Cancer, Blood Disorder
- Trial name
- NCT03176849
- Testing
- Vitamin D3, Standard Vitamin D3 Supplementation
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Phoenix Children's Hospital
Anemia, Iron Deficiency Anemia
Improving Iron Status of Children: Potential of Amaranth
Introduction: Iron deficiency anaemia remains a significant public health challenge. Localized food based approaches may offer a large opportunity to improve lives and address the widespread micronutrient deficiencies such as…
- Trial name
- NCT01224535
- Testing
- Maize and Amaranth
- Where
- Kenya
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Malnutrition, Cancer
Enteral Nutrition Support in Children and Adolescents With Cancer
CONTEXT AND OBJECTIVE: Tumor and its therapy have adverse effects on the nutritional status of cancer patients, leading to nutritional support.
- Trial name
- NCT01426750
- Testing
- industrialized oral supplementation (IOS) and tube feeding regimen (TFR) with Nutren
- Sponsor
- Grupo de Apoio ao Adolescente e a Crianca com Cancer
Tuberculosis, Severe Acute Malnutrition
Development of a Diagnostic Prediction Score for Tuberculosis in Hospitalized Children With Severe Acute Malnutrition (TB-Speed SAM)
TB-Speed SAM is a multicentric, prospective diagnostic cohort study conducted in two countries with high and very high TB incidence (Uganda and Zambia).
- Trial name
- NCT04240990
- Testing
- Development of a score and algorithm for TB treatment decision in hospitalised children with SAM.
- Where
- 3 sites in Uganda, Zambia
- Volunteers
- 603 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Malnutrition
Effectiveness Trial on Alleviation of Infant Malnutrition With Fortified Spread or Maize-Soy Flour Food Supplements
This study tests the hypothesis that moderately underweight but not severely wasted 6-17-month old infants receiving fortified spread or maize-spy flour as a food supplement for 12 weeks grow better during the supplementation…
- Trial name
- NCT00420758
- Testing
- Food supplement: fortified spread, Food supplement: maize-soy flour
- Where
- Malawi
- Volunteers
- 299 people
- Sponsor
- Tampere University
Anemia, Iron Deficiency
Lactoferrin for Treatment of Iron Deficiency Anemia.
Anemia is a great public health problem affecting both developing and developed countries. Iron deficiency anemia represents about 50% of causes of anemia worldwide.
- Trial name
- NCT04435574
- Testing
- Lactoferrin, Ferrous Sulfate
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Burn, Growth
Bone Mineral Density, Body Composition and Growth Following Severe Burn Injury
The purpose of this study is two-fold. The first is to establish that bone mineral density is diminished among children admitted to this regional burn center as compared to healthy non-burned children.
- Conditions
- Burn, Growth, Malnutrition
- Trial name
- NCT00285090
- Testing
- Calcium, Vitamin D, Calcium,Vitamin D, Calcium, VitaminD
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kathy Prelack, PhD, RD
Short Bowel Syndrome, Vitamin E Deficiency
Use of Tocofersolan (Vedrop®) to Prevent or Treat Refractive Vitamin E Deficiency in Infants and Children
Patients with short bowel syndrome or other forms of intestinal failure/fat malabsorption are unable to tolerate adequate oral or enteral feedings.
- Trial name
- NCT03582384
- Testing
- Tocofersolan
- Sponsor
- Boston Children's Hospital
Malnutrition
Assessment of the Nutritional Status of Children and Adolescents With Malignancies
The main objective of this study was the assessment of the nutritional status of children and adolescents aged between 0-18 with malignancies based on BMI percentiles and standard deviation scores, at diagnosis, during treatment…
- Trial name
- NCT02246452
- Volunteers
- 135 people
- Sponsor
- University of Hohenheim
Anemia, Iron-deficiency
Iron Deficiency Anemia, Iron Supplementation and Genomic Stability in Infants
This study compares weekly versus daily administration of iron for prevention of anemia in 6 months old infants. One third of the infants that are exclusively breast fed will not receive iron, the second third will receive iron…
- Trial name
- NCT03359447
- Testing
- Weekly Ferrous Sulfate, Daily Ferrous Sulfate
- Where
- Argentina
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Instituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri
Sickle Cell Disease, Malnutrition
Prevention of Malnutrition in Children With Sickle Cell Disease
The investigators are studying how to prevent malnutrition in children with sickle cell disease (SCD) in northern Nigeria. Community health workers will teach mothers about nutritious local foods that might help children grow…
- Trial name
- PMC-SCD (NCT06397118)
- Testing
- Maternal Nutrition Education, Standard Care
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Vanderbilt University Medical Center
Iron-deficiency
Stable Iron Isotope Method in HIV+ and HIV- Children
The objective of this study is to compare HIV infected children to uninfected children regarding 1) quantifying iron absorption from iron fortified maize porridge, lipid-based food supplements and oral iron supplements, and 2)…
- Trial name
- NCT03572010
- Testing
- FeFum fortified maize test meal, FeSO4 fortified LNS, FeSO4 supplement
- Where
- South Africa
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
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