Clinical trials: OCD
Depression, OCD
Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments
The study involves multiple retrospective analyses to understand the utilization of mental health treatments provided at Greenbrook and their effectiveness
- Conditions
- Depression, OCD, Anxiety Depression
- Trial name
- NCT06997549
- Testing
- Patients treated with NeuroStar TMS, Patients treated with Esketamine
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Neuronetics
Mental Disorders, Severe
Measuring Development of Brain Responses to Vocal Sounds in Babies of Mums With Mental Illness
CAPRI-Voc examines the differences in how speech and environmental sounds are processed in the infant brain as they grow from 9 to 12 months.
- Trial name
- CAPRI-Voc (NCT04350294)
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Obsessive-Compulsive Disorder
Study on Therapeutic Mechanism of Natural Psychotherapy for Neurosis
explore objective indicators of the efficacy of natural psychotherapy in the treatment of disorders such as obsessive-compulsive disorder
- Trial name
- NCT06443125
- Testing
- Natural psychotherapy
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Xiang Yang Zhang
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obsessive Compulsive Disorder
Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD
This study will examine the feasibility and potential efficacy of augmenting SRIs with minocycline. The study will assess whether the addition of minocycline leads to measurable changes in striatal glutamate (Glu) levels.
- Trial name
- NCT01695291
- Testing
- Minocycline
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- New York State Psychiatric Institute
Obsessive-compulsive Disorder
D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive Disorder
Cognitive-behavioral therapy (CBT) has proven efficacy for treatment of pediatric obsessive-compulsive disorder (OCD). Yet, CBT does not help all children and those who benefit often remain symptomatic upon treatment completion.
- Trial name
- NCT00864123
- Testing
- Cognitive-behavioral therapy, D-cycloserine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Body Dysmorphic Disorder
Fluoxetine in Pediatric Body Dysmorphic Disorder
This trial will study the effectiveness of the medication fluoxetine for children and adolescents ages 16 and younger with BDD who qualify.
- Trial name
- FDA BDD (NCT00245635)
- Testing
- Fluoxetine
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Montefiore Medical Center
Obsessive Compulsive Disorder (OCD)
NAC for Treatment-Resistant OCD and Other Related Disorders
This is a randomized, double-blind, placebo-controlled study investigating N-acetylcysteine (NAC) as an augmentation therapy for individuals with treatment-resistant obsessive-compulsive disorder (TR-OCD), studied within a…
- Trial name
- NCT06956157
- Testing
- N-Acetylcysteine Tablets
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Obsessive-Compulsive Disorder
A Wearable AI Feedback Tool for Pediatric OCD
To test the feasibility of implementing digitally enhanced psychotherapy and research in a community child and adolescent mental health center including the acceptability of the digital technology to patients, parents and…
- Trial name
- NCT05064527
- Testing
- wearable biosensor, Treatment as usual (TAU), Exposure and response prevention (ERP)
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Tourette Syndrome, Tourette's Disorder
Assessment of Children With Tic Onset in the Past 6 Months
The purpose of this research is to study why most children who have tics never develop Tourette syndrome but some do. In other words, we aim to find features that may predict whose tics will go away and whose tics will continue…
- Conditions
- Tourette Syndrome, Tourette's Disorder, Chronic Motor or Vocal Tic Disorder, Transient Tic Disorder
- Trial name
- NewTics (NCT01177774)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Washington University School of Medicine
Obsessive-Compulsive Disorder
TMS + Exposure Therapy for Pediatric OCD
The goal of this clinical trial is to compare different forms of transcranial magnetic stimulation (TMS) for improving the outcomes of Exposure with Response Prevention (ERP) in youth and young adults with Obsessive-Compulsive…
- Trial name
- NExT (NCT05931913)
- Testing
- Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex, Exposure with Response Prevention, Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Bradley Hospital
Anxiety Disorders, Generalized Anxiety Disorder
Computerized Intervention Targeting the Error-Related Negativity and Balance N1 in Anxious Children
Anxiety disorders are the most common form of psychopathology, and frequently begin in childhood, resulting in lifelong impairment.
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT05503017
- Testing
- Psycho-social, computerized intervention targeting error sensitivity, Psycho-social, computerized intervention on healthy lifestyle choices
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Florida State University
Generalized Anxiety Disorder
Pilot Study of Virtual Reality for Providing Exposure Therapy to Children
Drs. from the Mayo Clinic Rochester will plan and execute a feasibility study of the phase I prototype version of the Virtual Reality exposure therapy system. Dr.
- Trial name
- NCT03208348
- Testing
- Pilot Virtual Reality
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minnesota HealthSolutions
Prader-Willi Syndrome, Aggression
Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess whether Guanfacine Extended Release (GXR) reduces aggression and self injurious behavior in individuals with Prader Willi Syndrome (PWS).
- Conditions
- Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes
- Trial name
- PWS-GXR (NCT05657860)
- Testing
- Guanfacine Extended Release
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Maimonides Medical Center
Social Anxiety Disorder, Specific Phobia
Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment
The collection of patient self-report and diagnostic data will allow us to examine the efficacy of the treatment delivered in the McLean Anxiety Mastery Program.
- Conditions
- Social Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder, Panic Disorder
- Trial name
- NCT02305537
- Testing
- McLean Anxiety Mastery Program
- Where
- United States
- Volunteers
- 559 people
- Sponsor
- Mclean Hospital
Obsessive-compulsive Disorders and Symptoms in Children
Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children
This study will use magnetic resonance imaging (MRI) to assess the function and structure of overlapping task control circuits in children with a range of Obsessive-Compulsive symptoms (OCS).
- Trial name
- NCT03584945
- Testing
- Cognitive Behavioral Therapy, Community Referral as appropriate
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anxiety Disorders, Obsessive Compulsive Disorder
Evaluating Parenting Styles and Child Temperament Associated With Child Anxiety Disorders
This study will look at similarities and differences in family processes and child temperament among children with and without symptoms of anxiety disorders.
- Trial name
- NCT00517244
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Obsessive-Compulsive Disorder
Characterization of Childhood-Onset Obsessive-Compulsive Disorder
The purpose of this study is to learn more about Obsessive-compulsive Disorder (OCD) in children. OCD usually has a slow onset, and symptoms that may remain at a stable level over time.
- Trial name
- NCT00044239
- Where
- 4 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
OCD - Osteochondritis Dissecans
MRI Findings of Epiphyseal Growth Plate in Healthy Children
The purpose of the study is to determine if by using MRI changes can be identified changes early on in the knees of young children that may be at risk for developing osteochondritis dissecans.
- Trial name
- NCT03190200
- Testing
- MRI
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
OCD
Sertraline Combined With Fluvoxamine in the Treatment of Refractory Obsessive-compulsive Disorder
To verify that sertraline combined with fluvoxamine is superior to sertraline combined with aripiprazole
- Trial name
- NCT04963257
- Testing
- sertraline fluvoxamine, sertraline
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine