Clinical trials: OS
T-lymphoblastic Lymphoma
A Clinical Trial of Decitabine in Relapsed or Refractory T-lymphoblastic Lymphoma
To explore the safety, tolerability, and clinical effects of decitabine combined with Second-line chemotherapy regimens for patients with relapsed or refractory T-lymphoblastic lymphoma.
- Trial name
- NCT03558412
- Testing
- CODOX-M/IVAC, Decitabine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Mingzhi Zhang
Colorectal Cancer
Real World Study of Regorafenib Versus Fruquintinib in Colorectal Cancer
This is an observational, ambispective cohort study. The aim is to compare the efficacy and safety of regorafenib versus fruquintinib conducted in China.
- Trial name
- NCT04431791
- Testing
- Regorafenib, Fruquintinib
- Where
- China
- Volunteers
- 268 people
- Sponsor
- Peking University
Disorder Related to Bone Marrow Transplantation, Leukemia
Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
The goal of this clinical research study is to learn if combining busulfan with clofarabine and fludarabine can help control the disease better than the previous standard method (using busulfan and fludarabine alone) in patients…
- Conditions
- Disorder Related to Bone Marrow Transplantation, Leukemia, Transplantation Infection
- Trial name
- NCT01471444
- Testing
- Fludarabine, Clofarabine, Busulfan
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- M.D. Anderson Cancer Center
Ankle Impingement, Tendon Tear
Prevalence of Flexor Hallucis Longus Tears, Associated Os Trigonum Excision, and Return to Play
The study's aim is to determine the incidence of flexor hallucis tendon tears associated with os trigonum excision. The study will then compare the length until functional return to play of the patients who had flexor hallucis…
- Trial name
- NCT04467099
- Testing
- Foot Exam Follow-Up, X-ray, Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Forte Sports Medicine and Orthopedics
Ewing's Sarcoma
Study on VCD/IE in the Patients With Ewing's Sarcoma Family of Tumors (ESFT)
The purpose of this clinical trial was to evaluate the efficacy and tolerability of the sequential therapy of VCD/IE in the patients with ESFT.
- Trial name
- NCT00568464
- Testing
- VCR, CTX, ADM; IFO, VP-16
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Fudan University
Relapsed and Refractory, Diffuse Large B Cell Lymphoma
Apatinib for Relapsed and Refractory Diffuse Large B Cell Lymphoma
The purpose of this study is to evaluate the efficacy and safety of Apatinib for patients with Relapsed Refractory Diffuse Large B Cell Lymphoma.
- Trial name
- NCT03376958
- Testing
- Apatinib
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Zhengzhou University
Epimacular Membrane
Outcomes Based on the Pre-operative Integrity of IS/OS Junction in Idiopathic Epimacular Membrane Surgery
The aim of this study is to evaluate whether the pre-operative integrity or not of the inner segment (IS) and outer segment (OS) photoreceptoral junction may influence the post-operative visual acuity, the macular morphology…
- Trial name
- NCT04158791
- Testing
- pars plana vitrectomy with epimacular membrane removal and internal limiting membrane peeling
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Chronic Functional Constipation
Effectiveness & Safety of Promelaxin® Microenemas Against Macrogol 4000 P.O. in Chronic Constipation in Children 6-48 Months
The study is aimed at the efficacy and safety evalutation of the study treatments through a 2-weeks study period and the subsequent follow-up-
- Trial name
- NCT02751411
- Testing
- micro-enema with Promelaxin, Macrogol 4000
- Where
- 4 sites in Italy
- Volunteers
- 158 people
- Sponsor
- Aboca Spa Societa' Agricola
Endometriosis
A Study to Learn More About Using Dienogest to Treat Endometriosis in Chinese Participants
Endometriosis is a condition that affects women, usually during their reproductive years. In women with endometriosis, the tissue that lines the uterus starts to grow outside of the uterus.
- Trial name
- VISANNE OS (NCT04495855)
- Testing
- Dienogest (Visanne,BAY86_5258)
- Where
- China
- Volunteers
- 968 people
- Sponsor
- Bayer
Dravet Syndrome, Lennox Gastaut Syndrome
Research on Cognitive Effect of Cannabidiol on Dravet Syndrome and Lennox-Gastaut SyndromeGastaut Syndrome
The clinical trial "A Prospective Single-Center Single-Arm Clinical Trial on Cognitive Effect of Cannabidiol (CBD-OS®) on Dravet syndrome and Lennox-Gastaut Syndrome" is a single-group phase III study done in single tertiary…
- Trial name
- NCT04611438
- Testing
- Cannabidiol
- Where
- South Korea
- Volunteers
- 107 people
- Sponsor
- Yonsei University
Nasal and Nasal-type NK/T-cell Lymphoma
Treatment of Natural Killer/T Cell Lymphoma-I/II
The purpose of this study is to evaluate the efficacy and safety of DDGP regiment (gemcitabine，pegaspargase,cisplatin,dexamethasone) for patients with newly diagnosed stage I/II Natural Killer (NK)/T Cell Lymphoma.
- Trial name
- CTTNKTL-I/II (NCT01501136)
- Testing
- DDGP(cisplatin,dexamethasone,gemcitabine,pegaspargase), VIPD（cisplatin，Etoposide，Ifosfamide， dexamethasone，Mesna）, gemcitabine,pegaspargase,cisplatin,dexamethasone
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Mingzhi Zhang
Gastrointestinal Cancer
Next-generation Sequencing in Gastrointestinal Cancer
Liquid biopsy has been successfully applied to the treatment and diagnosis of cancer. cfDNA has been paid more and more attention in liquid biopsy.
- Trial name
- NCT03476057
- Testing
- Device： NGS sequencing cfDNA
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fujian Cancer Hospital
Intestinal Disease, Parasitic, Chronic Disease
Intestinal Parasites in Inhabitants of Kuyavian-Pomeranian Province in Poland
The goal of the proposed study is to assess the prevalence of intestinal parasitic diseases in adults and children. These invasions are included to "dirty hand diseases" (per os invasions), therefore it applies mainly preschool…
- Trial name
- NCT03490435
- Testing
- Tests for diagnosis of intestinal parasitic diseases
- Where
- Poland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Nicolaus Copernicus University
Avulsion Fracture
Lateral Ankle Treatment
This is a randomized control trial of pediatric patients with acute lateral ankle avulsion fractures. Patients will be randomized into two groups: Standard of care treatment which includes booting with early range of motion and…
- Trial name
- NCT07751068
- Testing
- Prolonged Immobilization (Casting), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Sports Injuries, Flexibility
THE MYOFASCIAL SYSTEM AND MINIMIZING THE RISK OS INJURY IN SPORT
The aim of the study is to evaluate the effect of myofascial self-release on muscle mechanical properties, performance, neuromuscular function, and injury risk reduction in young soccer players.
- Conditions
- Sports Injuries, Flexibility, Balance, Jumping Performance
- Trial name
- NCT06895720
- Testing
- Myofascial Self-Release
- Where
- Portugal
- Volunteers
- 65 people
- Sponsor
- Aveiro University
Osteosarcoma
Cancer Genome Study Using Samples From Patients Treated on Clinical Trial SHR1020-SHR-1210-II-OS
RATIONALE: Studying samples of tumor tissue from patients with advanced osteosarcoma refractory to chemotherapy in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to…
- Trial name
- CSSG-02 (NCT03997747)
- Testing
- cytology specimen
- Where
- 2 sites in China
- Volunteers
- 38 people
- Sponsor
- Peking University People's Hospital
Primary CNS Lymphoma (PCNSL)
Treatment of Primary CNS Lymphoma
The purpose of this study is to evaluate the efficacy and safety of FVD regiment (fotemustine, teniposide and dexamethasone ) for patients with primary CNS lymphoma.
- Trial name
- FVD (NCT01960192)
- Testing
- HD-MTX-Ara-C regimen, FVD regimen
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Mingzhi Zhang
Tonsillectomy, Adenoidectomy
Evaluating the Efficacy of Intravenous Acetaminophen (IV Tylenol) in Reducing Pain and Agitation in Pediatric Patients Undergoing Elective Tonsillectomy and/or Adenoidectomy
MetroHealth's main campus administers IV Tylenol as part of its pain management protocol for elective tonsillectomy/adenoidectomy, whereas Parma campus does not.
- Trial name
- PEACE (NCT07576985)
- Testing
- No Intervention: Observational Cohort
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- MetroHealth Medical Center