Clinical trials: OSAS
Sleep Apnea
Normal Polysomnography Values in Healthy Children and Adolescents in China
The study is designed to investigate normal polysomnographic respiratory values of Chinese healthy children and adolescents. By collecting the polysomnography (PSG) data and parameters of respiratory and sleep architecture，we…
- Trial name
- PSGNV (NCT02761902)
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Beijing Children's Hospital
Obstructive Sleep Apnea
Fentanyl Test in Children's Adenotonsillectomy
The purpose of this study is to discuss the relationship between the result of fentanyl test and required dosage of morphine for children with OSAS after adenotonsillectomy；and to evaluate the ability of predicting requested…
- Trial name
- NCT02484222
- Testing
- Fentanyl
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Down Syndrome, Obstructive Sleep Apnea
Down Syndrome Obstructive Sleep Apnea
The purpose of this study is to assess whether oxygen supplementation during sleep improves working memory and other clinical and patient-reported outcomes among children who have Down Syndrome (DS) with moderate to severe…
- Trial name
- DOSA (NCT06043440)
- Testing
- Oxygen
- Where
- 7 sites in United States
- Volunteers
- 230 people
- Sponsor
- Brigham and Women's Hospital
Pediatric Obstructive Sleep Apnea
The Use of Psychomotor Vigilance Testing in the Assessment of Pediatric Obstructive Sleep Apnea
Obstructive sleep apnea results in decreased attentiveness and response times in patients. The objective of this study is to quantify these consequences in pediatric OSA patients using an already established tool for examining…
- Trial name
- PVT (NCT01276860)
- Testing
- Psychomotor Vigilance Testing
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Sleep-disordered Breathing (SDB), Idiopathic Scoliosis
Effect of Adenotonsillectomy on Spinal Curve Magnitude in Children With Sleep-Disordered Breathing
This study aims to determine the effect of adenotonsillectomy (AT) surgery on the progression of spinal curvature in children with mild sleep-disordered breathing (SDB) and concurrent scoliosis, as well as its potential role in…
- Conditions
- Sleep-disordered Breathing (SDB), Idiopathic Scoliosis, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07332780
- Testing
- Adenotonsillectomy (AT) - removal of adenoids and tonsils, Watchful Waiting with Supportive Care
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Obstructive Sleep Apnea
Optimizing the Management of OSA in Children With Down Syndrome
The objective of this retrospective descriptive study is to assess current practices for the screening and surgical treatment of OSA in children with Down syndrome at the Strasbourg University Hospital and to disseminate a…
- Trial name
- SAOS-21 (NCT07334444)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Obstructive Sleep Apnea (OSA)
Evaluation of the Diagnostic Capacity of a Smart Mattress Versus Conventional Polysomnography
This project aims to develop and evaluate an innovative, non-invasive diagnostic system based on a smart mattress for detecting obstructive sleep apnea (OSA), as well as assessing overall sleep quality and identifying periodic…
- Trial name
- NCT07432919
- Testing
- Integrated polysomnographic assessment with smart mattress.
- Where
- 2 sites in Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospital San Pedro de Logroño
Obstructive Sleep Apnea
High Flow Nasal Cannula Therapy for Childhood OSA
The main objective of this study is to evaluate the efficacy of high-flow nasal cannula (HFNC) therapy in children with OSA. Children and adolescents aged 6 to 18 years old with a diagnosis of moderate-to-severe OSA requiring…
- Trial name
- NCT03933800
- Testing
- High flow nasal cannula, Continuous positive airway pressure
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- Chinese University of Hong Kong
Crossbite Teeth
Correlation Between Posterior Crossbite and Risk of Obstructive Sleep Apnea
Correlation Between Posterior Crossbite and Risk of Obstructive Sleep Apnea
- Trial name
- NCT07561606
- Testing
- Comparator, Interventions
- Volunteers
- 420 people
- Sponsor
- October University for Modern Sciences and Arts
Asthma, Bronchial, Bronchial Asthma
Sleep Apnea in Asthmatic Children and Teenagers
Asthma and sleep apnea are both respiratory diseases and one can worsen the other. Those who suffer from asthma have a higher risk of sleep apnea and sleep apnea can make the asthma more difficult to control.
- Conditions
- Asthma, Bronchial, Bronchial Asthma, Apnea, Sleep, Sleep Apnea, Mixed Central and Obstructive
- Trial name
- NCT03034447
- Testing
- Questionnaire, Lung Function Test, Home Sleep Study
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of São Paulo
Obesity, Obstructive Sleep Apnea Syndrome
Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents
Obesity has reached epidemic proportions in the United States with roughly 20% of American children being overweight and has serious consequences such as sleep apnea.Additionally, obesity is known to result in the earlier onset…
- Trial name
- NCT00222963
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Rochester
Obesity & Overweight, Pediatric Obesity
Ultrasound Assessment of Tongue Characteristics in Children and Adolescents With Obesity
This longitudinal observational study aims to validate ultrasound-based tongue markers related to tongue characteristics, including fat accumulation, morphologic and mechanical properties of the tongue in children and adolescents…
- Conditions
- Obesity & Overweight, Pediatric Obesity, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07370350
- Testing
- Submental ultrasound
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole Bruxelles-Brabant
Obstructive Sleep Apnea of Child
The Effect of Self-care Emphasizing on Balloon-Blowing Exercise Program on Severity of Sleep Apnea and Respiratory Muscle Strength Among School Age Children With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a common condition in school-age children, often leading to sleep disturbances and associated health issues.
- Trial name
- "SEES" (NCT06780982)
- Testing
- Balloon-Blowing exercise program, Standard nursing care
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Obesity, Obstructive Sleep Apnea
Treatment of Obstructive Sleep Apnea in Children: An Opportunity for Cardiovascular Risk Modification
Heart disease is a major cause of ill-health and death in adults. The risk factors for heart disease, if present in children, carry over into adult life.
- Conditions
- Obesity, Obstructive Sleep Apnea, Sleep Disorders, Cardiovascular Disease
- Trial name
- TREAT (NCT02403492)
- Testing
- cPAP, cPAP, Continuation, cPAP, Discontinuation
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- The Hospital for Sick Children
Obstructive Sleep Apnea Syndrome
Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy
The study will evaluate the post-operative morphine-sparing effect, pain reduction, and side effects of a continuous ketamine infusion after tonsillectomy in pediatric patients.
- Trial name
- KOSATA (NCT02425202)
- Testing
- Ketamine, Saline infusion
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Tonsillitis, Obstructive Sleep Apnea
Study of Efficacy and Adverse Effects: Vessel Sealing System Tonsillectomy Versus Cold Knife Tonsillectomy
This study was planned to compare vessel sealing system tonsillectomy (VSST) to the traditional cold knife tonsillectomy (CKT) with special regard to intraoperative bleeding, operative time, postoperative pain and hemorrhage.
- Trial name
- NCT00636402
- Testing
- Cold Knife Tonsillectomy, Vessel Sealing System Tonsillectomy
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Chulalongkorn University
Obstructive Sleep Apnea
Outcome of Laser or Debrider Tonsillotomy Versus Tonsillectomy in Obstructive Sleep Apnea
Tonsil surgery for children suffering from obstructive sleep apnea have significant post operative morbidity including pain and occasionally bleeding. This morbidity is partly caused by post surgical inflammation.
- Trial name
- TVLOD (NCT01319058)
- Testing
- Tonsillectomy, laser tonsillotomy, debrider tonsillotomy
- Where
- Israel
- Volunteers
- 88 people
- Sponsor
- Soroka University Medical Center
Obstructive Sleep Apnea (Moderate to Severe), Obstructive Sleep Apnea
A Mindfulness-Based Intervention to Improve CPAP
The main purpose of this study is to assess the effectiveness of a mindfulness-based intervention in improving CPAP use compared to online peer support
- Trial name
- NCT05499286
- Testing
- Mindfulness Program
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- The Hospital for Sick Children
Adenotonsillar Hypertrophy, Tonsillitis
Comparison of Floseal Hemostasis Tonsillectomy With Coblation Tonsillectomy and Cautery Hemostasis Tonsillectomy
The purpose of this study is to evaluate a new method of hemostasis, floseal gel, in tonsillectomy and adenoidectomy, with the goal of decreasing post operative and intraoperative morbidity.
- Conditions
- Adenotonsillar Hypertrophy, Tonsillitis, Obstructive Sleep Apnea
- Trial name
- NCT00459927
- Testing
- Floseal tonsillectomy, Coblation tonsillectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Sleep Apnea, Obstructive, Children
Real Life Pediatric Obstructive Sleep Apnea
OBJECTIVES: PRIMARY: To analyze the cognitive alterations in children with Obstructive Sleep Apnea OSA in different age groups and changes at 12 months after treatment with a protocol based on usual clinical practice.
- Trial name
- RELIPOSA (NCT03950466)
- Where
- 2 sites in Spain
- Volunteers
- 1,200 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica