Clinical trials: Obesity/therapy
Childhood Obesity
Parent Partnership Project
To evaluate the acceptability and feasibility of peers as interventionists in delivering family-based behavioral pediatric weight control intervention.
- Trial name
- NCT01789944
- Testing
- Behavioral: Family-based behavioral intervention
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Seattle Children's Hospital
Obstructive Sleep Apnea, Obesity
Obesity and Obstructive Sleep Apnea (OSA) in Children
The goal of this research is to study the prevalence of sleep disordered breathing and associated morbidity in obese children and to examine the role of diet and physical activity in the treatment of sleep-disordered breathing in…
- Trial name
- NCT01135147
- Testing
- Diet, Surgery
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Obesity, Childhood
Vyvanse in Children Aged 6 to 12 Years
This study will randomize children who have difficulty maintaining a healthy weight to one of two treatment groups: lifestyle therapy plus lisdexamfetamine or lifestyle therapy plus placebo.
- Trial name
- NCT05416125
- Testing
- Lisdexamfetamine Dimesylate, Lifestyle therapy
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity
For the Health of Our Children--Clinic Based Treatment of Childhood Obesity
Childhood obesity is a major public health problem in the U.S. Currently approximately one in three children is considered overweight or obese. Most overweight children grow to become overweight adults.
- Trial name
- NCT01625910
- Testing
- Behavioral counseling
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity
A Study to Assess the Compliance and Impact on Weight of Kurbo, a Pediatric Centered Weight Loss App
Kurbo is a health and fitness app that is targeted toward the pediatric population. It utilizes games and activities to educate children about healthy eating, portion control/size and exercise.
- Trial name
- Kurbo (NCT02880254)
- Testing
- Kurbo, Personal Health Coach
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Obesity
A Study to Determine the Effectiveness of a Self-regulation Program to Treat Pediatric Obesity
The objective of this study is to pilot test, evaluate and compare the effects of Cue Reactivity and Sensitivity Training (CRST) and Children's Appetite Awareness Training (CAAT) in 48 children aged 8-12 years old.
- Trial name
- ROC (NCT01442142)
- Testing
- CAAT: Appetite Awareness, CRST: Volcravo, Combined CAAT and CRST program
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Sarcopenic Obesity
Dietary Intake, Sarcopenic Obesity, and Other Treatment-Related Outcomes in Indian Children With Acute Lymphoblastic Leukemia
Sarcopenic obesity occurs when there is a loss of muscle and gain of fat in the body. With this study, the investigators will explore how nutritional status at the beginning of the treatment can cause changes in your child's body…
- Trial name
- TATA (NCT03974893)
- Testing
- Vegetarian Diet
- Where
- India
- Volunteers
- 115 people
- Sponsor
- Columbia University
Obesity, Obesity, Childhood
Community Based Obesity Prevention and Treatment Programme "6-10-14 for Health"
"6-10-14 for Health" is an integrated weight-loss intervention programme for obese children from Gdansk municipality. Both participants of the programme and their family members are offered a 12-month integrated intervention…
- Conditions
- Obesity, Obesity, Childhood, Health Program, Body Weight Changes
- Trial name
- NCT04143074
- Testing
- multidisciplinary behavioral intervention
- Where
- Poland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Michał Brzeziński
Generalized Lipodystrophy
A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)
This study is researching an experimental drug called mibavademab. The study is focused on participants with GLD who have been on metreleptin treatment for at least 6 months with no change in dose for the last 3 months.
- Trial name
- NCT06548100
- Testing
- mibavademab
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Regeneron Pharmaceuticals
Obesity
Sensible Treatment of Obesity in Rural Youth . . .
Project STORY (Sensible Treatment of Obesity in Rural Youth) will entail a three-arm randomized controlled trial to test the effectiveness of interventions designed to promote successful weight management in an important…
- Trial name
- NCT00248677
- Testing
- Behavioral Family-Based Intervention, Behavioral Parent-Based Intervention
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Florida
Childhood Obesity
Predictors of Success in an Intervention Program for the Treatment of Childhood Obesity
The child health and sports center, at the Meir Medical Center, runs for over 10 years an intervention program to treat obese children. The program includes physical activity, nutritional intervention and behavioral treatment.
- Trial name
- NCT01578863
- Testing
- Intervention program for obese children
- Where
- Israel
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Fatty Liver, Nonalcoholic Steatohepatitis
Treatment of Nonalcoholic Steatohepatitis With Pioglitazone
This study will evaluate the effectiveness of pioglitazone, a new diabetes medicine, on decreasing insulin resistance and improving liver disease in patients with nonalcoholic steatohepatitis (NASH).
- Trial name
- NCT00013598
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity & Overweight, Diabete Type 2
Traditional Chinese Medicine Fasting Therapy, Ketone Levels, and Metabolic Improvements
This is a retrospective study using existing medical records. The purpose is to learn how Traditional Chinese Medicine (TCM) fasting therapy affects metabolism.
- Conditions
- Obesity & Overweight, Diabete Type 2, Metabolic Syndrome
- Trial name
- NCT07840807
- Testing
- Traditional Chinese Medicine Fasting Therapy
- Where
- China
- Volunteers
- 1,149 people
- Sponsor
- The Seventh Affiliated Hospital of Sun Yat-sen University
Childhood Obesity, Adolescent Obesity
A Multicenter Study for Evaluating a Digital Support System in Childhood Obesity Treatment
Evira is a digital support system newly developed for treatment of childhood obesity. Through daily weighings at home using a special scale together with a message function in the Evira application, enabling fast and easy…
- Conditions
- Childhood Obesity, Adolescent Obesity, mHealth, Personalized Medicine
- Trial name
- EurEvira (NCT04917601)
- Testing
- Evira Care treatment, Standard Lifestyle Care
- Where
- 5 sites in Italy, Norway and 2 more
- Volunteers
- 680 people
- Sponsor
- Karolinska Institutet
Gamification in Health Education, Health Education
Study on the Effect of a Gamified Health Education Programme on Primary School Children
This randomised study evaluates the effectiveness of Health Education through a Gamified Health Programme on diet, sedentary behaviour and daily physical activity in primary school children.
- Trial name
- BELLOTEX-SALUD (NCT07276412)
- Testing
- Intervention - A, Intervention - B, Intervention - C
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Bardet Biedl Syndrome (BBS), Bardet Biedl Syndrome
Real-World Effects of MC4R Agonist Therapy in BBS and Severe Genetic Obesity
Bardet-Biedl syndrome (BBS) and other rare disorders associated with impairment of the melanocortin-4 receptor (MC4R) pathway are characterized by severe early-onset obesity, hyperphagia, and substantial morbidity.
- Conditions
- Bardet Biedl Syndrome (BBS), Bardet Biedl Syndrome, Bardet-Biedl Syndrome (BBS), Alstrom Syndrome
- Trial name
- REAL-MC4 (NCT07674290)
- Testing
- Setmelanotide
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Tom Hühne
Diabetes, Diabetes Mellitus, Type 1
Observational Study on Levemir® in Obese Diabetic Patients
This study is conducted in Europe. The aim of this observational study is to investigate the effect of switch from other basal insulin treatments to Levemir® on body weight in obese diabetic patients.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- KILOS (NCT00849342)
- Testing
- insulin detemir
- Where
- 2 sites in Netherlands, Slovenia
- Volunteers
- 580 people
- Sponsor
- Novo Nordisk A/S
Morbid Obesity, Bariatric Surgery
Registry on Obesity Surgery in Adolescents
While bariatric surgery is established as a safe and effective alternative with well-defined risks for severely obese adults, little has been published on its use in children.
- Conditions
- Morbid Obesity, Bariatric Surgery, Adolescent Obesity
- Trial name
- ROSA (NCT03203161)
- Testing
- bariatric surgery
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Queen Fabiola Children's University Hospital
Prader-Willi Syndrome
Regulating Together for Prader-Willi Syndrome: A Group Behavioral Therapy for Emotion Dysregulation
The goal of this study is to help teens with Prader-Willi Syndrome (PWS) and their families learn practical strategies for managing issues like irritability, meltdowns, and anxiety.
- Trial name
- RT-PWS (NCT07607730)
- Testing
- Regulating Together group therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Mercy Hospital Kansas City
Childhood Obesity, Treatment Adherence
The Evira Study: Additional Support During Obesity Treatment
The goal of this clinical trial is to evaluate the effect of adding a digi-physical treatment tool as a complement to the local treatment with obesity medication in adolescents with obesity.
- Trial name
- NCT06836284
- Testing
- Digi-physical treatment tool, Evira, Obesity medication with liraglutide or semaglutide
- Where
- 3 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet