Clinical trials: Obesity/therapy
Protocol #1:Behavioral Therapy + Placebo or Sibutramine, Protocol #2: Behavioral Therapy + Meal Replacement or Conventional Food
Adolescent Weight Management Study
Protocol #1:The goals of this study was to examine whether increased weight loss in obese adolescent is induced when the weight loss medication sibutramine is added to a family-based, behavioral weight control program.
- Trial name
- NCT00212173
- Testing
- Sibutramine, Slim Fast
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Prevention of Childhood Obesity, Community Health Education
EFFECT OF A ONLINE NUTRITION EDUCATION PROGRAM IN PRESCHOOLER'S FAMILIES ON THEIR ADHERENCE TO THE MEDITERRANEAN DIET
Questions: What's the effect of an online nutritional educational program in preschoolers families on the adherence to the mediterranean diet? What's the effect of this program on the BMI at 3 years follow-up? Study Description A…
- Trial name
- ELIKUME (NCT06828367)
- Testing
- Online family educational intervention and cooking workshop
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet
Obesity, Childhood, Feeding Behavior
Family Empowerment for Enhanced Development
This study evaluates the feasibility and preliminary effects of offering the Mealtime PREP intervention to low-income families with young children.
- Trial name
- Project FEED (NCT03641716)
- Testing
- Mealtime PREP Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Morbid Obesity, Cardiovascular Disease
Omega-3 Fatty Acid Status in Morbid Obesity Before and After Surgical Treatment
The purpose of this study is to determine the concentration of omega-3 fatty acids in plasma, blood and abdominal fat before and after bariatric surgery to provide guidance for future studies.
- Conditions
- Morbid Obesity, Cardiovascular Disease, Fatty Acid Levels
- Trial name
- NCT00558532
- Testing
- Bariatric Surgery
- Where
- United States
- Sponsor
- University of Cincinnati
Pediatric Obesity
Behavioral Rx & Nutrition in Pediatric Chronic Disease
The objective of this project is to pilot test a behavioral intervention for modifying the diet and physical activity patterns of overweight preschool children through improved parenting and nutritional education(LAUNCH).
- Trial name
- LAUNCH (NCT01018121)
- Testing
- LAUNCH, Pediatrician Counseling
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Childhood Obesity
Motivation Approach for Childhood Obesity Treatment
In a recent study, we have demonstrated that the motivational therapy approach to treat childhood obesity is highly effective at clinical and metabolic levels. This efficacy has been proved in a clinical outpatient setting.
- Trial name
- OBEMAT (NCT02889406)
- Testing
- Motivational intervention
- Where
- Spain
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Obesity &Amp; Overweight, Bulimia Nervosa
Training App for Inhibitory Control Towards Food
The aim of this project is to test the feasibility, acceptability and clinical impact of a mobile app-based intervention (FoodTraining) to strengthen food-related inhibitory control over 4 weeks, in a sample of people with eating…
- Conditions
- Obesity &Amp; Overweight, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- FoodT-RCT (NCT07075952)
- Testing
- Food-specific inhibitory control training delivered through the FoodTraining App, Waiting list
- Where
- Italy
- Volunteers
- 113 people
- Sponsor
- University of Padova
Overweight, Obesity
Prediction of Weight Gain by Children and Adolescents
The 'Meir children's sport and health center' runs a multi-disciplinary intervention program for the treatment of overweight and obese children and adolescents.
- Trial name
- NCT01111812
- Where
- Israel
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Obesity & Overweight, Orthodontic Treatment
Impact of Increased Body Mass Index on Adolescent Fixed Orthodontic Treatment. A Prospective Longitudinal Study
The goal of this prospective observational study is to assess the influence of increased body mass index (BMI) on various oral health and orthodontic-related parameters in adolescents undergoing orthodontic therapy (OT) with…
- Trial name
- NCT07217756
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Genetic Obesity, Obesity
Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity
The purpose of the study was to determine the effect of setmelanotide (RM-493) on weight, hunger assessments, and other factors in participants with rare genetic disorders of obesity.
- Conditions
- Genetic Obesity, Obesity, Obesity Due to Melanocortin 4 Receptor Deficiency
- Trial name
- NCT03013543
- Testing
- Setmelanotide
- Where
- 58 sites in United States, Canada and 7 more
- Volunteers
- 213 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Obesity, Diabetes
Treatment of Morbidly Obese Adolescent With a Duodena-jejunal Liner
Obesity and its complications have a significant effect on morbidity and mortality in these subjects. Especially at risk are subjects with extremely increased BMI (above 99th percentile for age and gender in adolescents).
- Conditions
- Obesity, Diabetes, Metabolic Syndrome
- Trial name
- NCT02183935
- Testing
- Duodena-jejunal liner
- Where
- Slovenia
- Volunteers
- 22 people
- Sponsor
- University Medical Centre Ljubljana
Childhood Obesity
Gardner Packard Healthy Lifestyles Program
Gardner GOALS is a 6 month program for treatment of childhood obesity that consists of twice monthly telehealth meetings with a health educator.
- Trial name
- NCT05107648
- Testing
- Gardner GOALS
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Stanford University
Obesity Associated With Defects in Leptin-melanocortin Pathway
Long Term Extension Trial of Setmelanotide
This was a long-term extension trial to study the safety and tolerability of continued setmelanotide treatment in participants who had completed a previous clinical trial on treatment with setmelanotide for obesity associated…
- Trial name
- NCT03651765
- Testing
- Setmelanotide
- Where
- 27 sites in United States, Canada and 6 more
- Volunteers
- 205 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Obesity, Cardiovascular Diseases
High-intensity Exercise Training or Multidisciplinary Treatment in Extremely Obese Adolescents
The aim of the present study was to determine the effects of a multidisciplinary approach and intensity-controlled interval training on cardiovascular risk factors in overweight adolescents
- Trial name
- NCT00682266
- Testing
- intensity controlled interval training (AIT), Multidisciplinary approach (MTG)
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Oligospermia
Aromatase Inhibitors in the Treatment of Male Infertility
Obesity is associated with an increase in blood levels of estrogen. Estrogen or "female hormone" is believed to have a negative effect on sperm production.
- Trial name
- NCT00440180
- Testing
- Anastrozole
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Obesity, Atherosclerosis
Observational Study of Early Metabolic and Vascular Changes in Obesity
To work against the increasing burden of obesity, the STYJOBS / EDECTA (STYrian Juvenile OBesity Study / Early DetECtion of Atherosclerosis) project was started at the Medical University of Graz in 2003.
- Conditions
- Obesity, Atherosclerosis, Inflammation, Adiponectin Deficiency
- Trial name
- STYJOBS (NCT00482924)
- Testing
- Lifestyle intervention
- Where
- Austria
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Obesity/therapy, Prevention and Control
Cognitive-Behavioral Intervention to Increase Tummy Time Practice and Maintain Healthy Weight in Infants
Childhood obesity is a serious health problem worldwide evidenced by its high prevalence, specifically for the age group called the first 1000 days of life.
- Trial name
- NCT06616467
- Testing
- Tummy Time for the prevention of childhood obesity
- Where
- Mexico
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Pediatric Overweight
Examining the Role of Executive Functioning in Family-Based Intensive Health Behavior and Lifestyle Treatment
The objectives of this open trial feasibility study are to examine the impacts of intensive health behavior and lifestyle treatment (IHBLT) on youth and caregiver executive functioning (EF), weight status, health behaviors…
- Trial name
- Healthy LIFT (NCT06969235)
- Testing
- intensive health behavior and lifestyle treatment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Prader Willi Syndrome, Obsessive-compulsive Disorder
Behavioral Treatment of Obsessive-Compulsive Symptoms in Youth With Prader-Willi Syndrome: A Pilot Project
Obsessive-compulsive (OC) symptoms are often present among youth with Prader-Willi Syndrome (PWS). They are also associated with considerable problems in the daily functioning of the child and his/her family.
- Trial name
- NCT00742664
- Testing
- Cognitive-behavioral therapy, Wait-list control
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of South Florida
Obesity
Parents as the Agent of Change for Childhood Obesity
The overall intent of this study is to explore a promising mode for delivering treatment for childhood obesity via parent education only, and to evaluate the cost effectiveness compared to the current gold standard treatment of…
- Trial name
- PAAC (NCT01197443)
- Testing
- Parent-only Group, Parent + Child Group
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego