Clinical trials: Obesity & Overweight Sleep
Obstructive Sleep Apnea, Obesity
Obesity and Obstructive Sleep Apnea (OSA) in Children
The goal of this research is to study the prevalence of sleep disordered breathing and associated morbidity in obese children and to examine the role of diet and physical activity in the treatment of sleep-disordered breathing in…
- Trial name
- NCT01135147
- Testing
- Diet, Surgery
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Sleep, Obesity
Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors
The proposed study aims to determine whether an intervention to increase sleep in school-age children is associated with positive changes in eating, activity behaviors and zBMI.
- Trial name
- NCT01508793
- Testing
- Optimize Sleep
- Where
- 2 sites in United States
- Volunteers
- 103 people
- Sponsor
- The Miriam Hospital
Physical Activity, Obesity
Effectiveness of a Physical Activity Intervention to Prevent Obesity and Improve Academic Performance
Coordinated project whose objectives are: a) to test the effectiveness of a promotion of physical activity intervention (MOVI-KIDS) on preventing obesity; and b) to improve the academic performance in both children with and…
- Conditions
- Physical Activity, Obesity, Children, Academic Underachievement Disorder
- Trial name
- MOVI-KIDS (NCT01971827)
- Testing
- MOVI-KIDS
- Where
- Spain
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Atherosclerosis, Cardiovascular Risk Factor
Early Vascular Ageing in the YOUth
This is a single-center observational study on adolescents to determine predictors of the early steps of the formation of atherosclerosis and to quantify their influence on Intima-Media-Thickness of the carotid artery and the…
- Conditions
- Atherosclerosis, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Pathology
- Trial name
- EVA4YOU (NCT04598685)
- Where
- Austria
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Obesity
Weight Gain in First-year University Students
The transition to university from secondary school comes with many changes to living arrangements, dietary and alcohol intake, physical activity, and stress.
- Trial name
- NCT05856734
- Testing
- Weight and body composition change, Change in dietary intake, Change in physical activity
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Non Alcoholic Fatty Liver Disease
The Role of Obstructive Sleep Apnea in Children With Fatty Liver Disease
The purpose of this study is to examine whether CPAP therapy can reduce or eliminate hepatic fat accumulation in obese children and adolescents.
- Trial name
- NCT02134522
- Testing
- Continuous positive airway pressure (CPAP).
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Yale University
SDB, T2DM
Sleep Disordered Breathing and Impaired Glucose Homeostasis in Obese Children
SDB has been identified as an important risk factor for insulin resistance and the metabolic syndrome. In a recent study in patients with SDB and T2DM it was shown that CPAP therapy can lead to improvements in postprandial…
- Conditions
- SDB, T2DM, Obesity
- Trial name
- NCT02037100
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obesity, Obstructive Sleep Apnea (Moderate to Severe)
Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in Adolescents
The research study is being done to test heated humidified high-flow air (HHF), as a treatment for OSA.
- Conditions
- Obesity, Obstructive Sleep Apnea (Moderate to Severe), Central Sleep Apnea
- Trial name
- NCT05354401
- Testing
- HHF
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Prader-Willi Syndrome
A Study of Pitolisant in Patients With Prader-Willi Syndrome
This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome.
- Trial name
- NCT06366464
- Testing
- Pitolisant tablet
- Where
- 57 sites in United States, Australia and 11 more
- Volunteers
- 134 people
- Sponsor
- Harmony Biosciences Management, Inc.
Obesity, Childhood, Short Sleep
Brief Behavioral Sleep Intervention for Obesity Prevention in Primary Care
The goal of this study is to compare two different approaches to help families with children 6-11 years enhance nighttime sleep: 1) working one-on-one with a nurse to learn effective behavioral strategies to try to improve…
- Conditions
- Obesity, Childhood, Short Sleep, Obesity Prevention
- Trial name
- Rx SLEEP (NCT06810557)
- Testing
- Optimize Sleep Primary Care (OSPC), Enhanced Usual Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Temple University
Obesity, Sleep
Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors-Renewal
Enhancing children's sleep may be a novel approach for prevention of obesity and cardiovascular (CV) disturbance. Observational studies with children demonstrate that short sleep increases risk of obesity and other CV risk…
- Trial name
- NCT03186508
- Testing
- Optimize Sleep (OS), Optimize Sleep-Plus (OS-Plus)
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Temple University
Overweight Adolescents, Obesity, Adolescent
Effects of the Daily Mile Program on General Health in Overweight/Obese Schoolchildren
This study is a clinical trial will be carried out during academic term to assess the potential effects of the Daily Mile program on health-related physical fitness and sleep quality on overweight/obese schoolchildren.The trial…
- Trial name
- NCT05862506
- Testing
- Daily Mile
- Where
- Colombia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Unidades Tecnológicas de Santander
Sleep
A Sleep and Media Use Intervention to Improve Adolescents' Weight and Risk of Type 2 Diabetes
This study aims to assess the effects of a sleep and media intervention on adolescents' overall health.
- Trial name
- NCT02451436
- Testing
- Sleep and Media Use Intervention, Study Skills Control Group
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity, Childhood, Overweight, Childhood
Sleep and Stigma: Novel Moderators in the Relationship Between Weight Status and Cognitive Function
The investigators aim to assess the relationship between overweight/obesity and decreased cognitive function in adolescents. While this relationship has been seen in past literature, the causal mechanisms are still unclear.
- Trial name
- NCT04346433
- Testing
- Restricted Sleep, Adequate Sleep
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity, Obstructive Sleep Apnea Syndrome
Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents
Obesity has reached epidemic proportions in the United States with roughly 20% of American children being overweight and has serious consequences such as sleep apnea.Additionally, obesity is known to result in the earlier onset…
- Trial name
- NCT00222963
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Rochester
Sleep Apnea, Central, Prader-Willi Syndrome
Oxygen Versus Medical Air for Treatment of CSA in Prader Will Syndrome
The aim of this study is to determine if treatment with Medical Air (21% oxygen in room air) compared to supplemental oxygen (100% oxygen) will lead to similar improvements in the central apnea-hypopnea index (CAHI) for infants…
- Trial name
- NCT03031626
- Testing
- Medical Air vs Oxygen
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- The Hospital for Sick Children
Obstructive Sleep Apnea, Postoperative Respiratory Complications
A Multicenter Retrospective Analysis of Postoperative Respiratory Complications in Children With Obstructive Sleepapnea
This retrospective observational study aims to evaluate postoperative respiratory complications (PORC) after (adeno)tonsillectomy in children with OSA.
- Conditions
- Obstructive Sleep Apnea, Postoperative Respiratory Complications, Adenotonsillectomy, Child Obesity
- Trial name
- MRA PORC (NCT07305168)
- Where
- 2 sites in Belgium, Hungary
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Pediatric Obesity, Sleep Apnea, Obstructive
Exercise and Venous Compression on Upper Airway Resistance in Obese Teenagers With OSA
The purpose of this study is to assess the effects of physical exercise, associated or not with venous compression of the leg, on obstructive sleep apnea (OSA) severity and upper airway resistance in obese teenagers.
- Trial name
- OBESOMAC (NCT02588469)
- Testing
- Interventional group, Control group
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Sleep Apnea, Obstructive, Pediatric Obesity
Obstructive Sleep Apnea in Obese Children and Teenagers - Occurrence and Importance of Intervention
The prevalence of childhood obesity has increased at an alarming rate over the last decades, both globally and in Denmark. There are a number of serious sequelae related to obesity, such as hypertension, hypercholesterolemia…
- Trial name
- NCT02463201
- Testing
- Weight loss
- Where
- 2 sites in Denmark
- Volunteers
- 236 people
- Sponsor
- Zealand University Hospital