Clinical trials: Obesity in Children
Prader-Willi Syndrome, Hyperphagia
Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome
The investigators propose a randomized double-blind 8 week treatment trial of intranasal oxytocin (IN-OXT) vs. placebo in 24 subjects aged 5 to 18 years with PWS in order to assess IN-OXT's affect on (1) Eating behaviors (2)…
- Trial name
- OXT-PWS (NCT02629991)
- Testing
- Intranasal Oxytocin (IN-OXT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Montefiore Medical Center
Adolescent Overweight, Adolescent Obesity
Improving Sleep, Decision-Making, and Eating in Adolescents With Obesity
This study is being performed to understand the effects of a lifestyle modification and sleep intervention on weight loss outcomes in adolescence.
- Conditions
- Adolescent Overweight, Adolescent Obesity, Sleep, Eating Behaviors
- Trial name
- STAR (NCT06745570)
- Testing
- Lifestyle Modification and Sleep Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
Obesity, Overweight
Mobile Attention Retraining in Overweight Female Adolescents
Background: People are constantly exposed to unhealthy foods. Some studies of adults show that training attention away from unhealthy foods might reduce overeating.
- Conditions
- Obesity, Overweight, Binge Eating, Healthy Volunteers
- Trial name
- NCT02977403
- Testing
- Attention Bias Retraining
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infant, Obesity
The Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) Study
This study will test an intervention program designed to provide developmentally appropriate guidance to parents of infants on responsive parenting and healthy lifestyle to see if that intervention will prevent rapid weight gain…
- Trial name
- INSIGHT (NCT01167270)
- Testing
- Child Safety Insights, Parenting Insights
- Where
- 2 sites in United States
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Ian M. Paul, MD
Obesity, Childhood
Acetaminophen Dosing in Obese Adolescents
Although there are numerous studies investigating the pharmacokinetic properties of intravenous acetaminophen in infants and children with normal weight, there are none in the obese pediatric patient .
- Trial name
- NCT03192566
- Testing
- Tylenol
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Obesity, Childhood Obesity
The Effects of Integrative Neuromuscular Training on Physical Function in Overweight Children
Childhood obesity is an ongoing and increasing issue, resulting in changes in body mass which cause biomechanical alterations in the lower limbs.
- Trial name
- NCT05724303
- Testing
- 8-week neuromuscular training program
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Childhood Obesity
Brighter Bites - Access, Continuity and Education With Fruits and Vegetables
The purpose of the research is to find out how well a new nutrition program works for elementary school students and their families. This program is called Brighter Bites.
- Trial name
- Brighter Bites (NCT02726529)
- Testing
- Brighter Bites, CATCH
- Where
- United States
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Obesity, Childhood, Diabetes Mellitus, Type 2
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort study is a unique and comprehensive longitudinal study of 630 Caucasian children and their parents that was designed to investigate the natural history and…
- Conditions
- Obesity, Childhood, Diabetes Mellitus, Type 2, Cardiovascular Risk Factor, Pediatric ALL
- Trial name
- QUALITY (NCT03356262)
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Obesity, Childhood, Antibiotic Side Effect
Microbiome, Antibiotics, and Growth Infant Cohort
This cross-disciplinary study will assemble and longitudinally follow a large, diverse birth cohort to determine the relationships between early life antibiotic exposure, microbiome development, growth, antibodies, and…
- Trial name
- MAGIC (NCT03001167)
- Where
- United States
- Volunteers
- 509 people
- Sponsor
- Children's Hospital of Philadelphia
Diet Intervention, Physical Activity Intervention
Obesity Prevention in Children and Young People Treated for Acute Lymphoblastic Leukaemia with ALLTogether
Background Leukaemia is the most common cancer in children with 800 diagnoses per year in England. To survive, children need strong treatments like chemotherapy and steroids given usually through clinical trials.
- Conditions
- Diet Intervention, Physical Activity Intervention, Standard Care Control
- Trial name
- BREVARY (NCT06846294)
- Testing
- Diet, Diet and physical activity
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Exeter
Obesity, Adolescent
PathMate2: The Impact of Health Information System Services on the Effects of Therapy in Overweight Teenagers
Randomised controlled trial in overweight adolescents using a health App.
- Trial name
- PM2 (NCT03270423)
- Testing
- PathMate2, PathMateS
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Ostschweizer Kinderspital
Psoriasis, Obesity
Cross-sectional Evaluation of Biological Markers of Cardiovascular Disease in Children and Adolescents With Psoriasis
Hypothesis 1: Patients with psoriasis will have clinical and laboratory assessments differing from control patients. Hypothesis 2: Patients with psoriasis will have laboratory alterations that correlate with other clinical…
- Conditions
- Psoriasis, Obesity, Cardiovascular Risk, Inflammation
- Trial name
- NCT01122095
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Overweight, Obesity
Intervention Study for Overweight and Obese Kindergarten Children
The goal of the this study is to create an interdisciplinary program which includes intervention in the fields of nutrition, physical activity and behavior in order to treat obesity and overweight among kindergarten children and…
- Conditions
- Overweight, Obesity, Physical Fitness
- Trial name
- NCT01285063
- Testing
- Multidisciplinary intervention: physical activity, dietary instructions and behavioral treatment.
- Where
- Israel
- Sponsor
- Meir Medical Center
Obese Children and Adolescents
Topiramate and Severe Obesity
The purpose of this study is to evaluate the efficacy of Topiramate on the decrease of Body Mass Index compared to placebo at 9 months.
- Trial name
- TOBI (NCT02273804)
- Testing
- Topiramate
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Childhood Obesity
Etiological Factors, Risk Factors and Early Stages of Chronic Disease in Different Degrees of Childhood Overweight
Children and adolescents with overweight and obesity are predisposed to significant health problems. It is known that childhood obesity can adversely affect almost every organ system, and if left untreated, the major impact of…
- Trial name
- NCT02091544
- Testing
- Lifestyle intervention
- Where
- Netherlands
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pediatric Obesity
The Early Stockholm Obesity Prevention Project in China
This is a cohort study where families with infants are followed closely for three years. It aims to assess if parental weight status (normal weight vs.
- Trial name
- ES-China (NCT02409875)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Huazhong University of Science and Technology
Pediatric Obesity, Risk Reduction Behavior
FirstStep2Health Intervention
This project will determine the preliminary efficacy of an innovative intergenerational intervention among Head Start preschoolers, aged 3-5 years, and their caregivers.
- Conditions
- Pediatric Obesity, Risk Reduction Behavior, Early Intervention, Intergenerational Relations
- Trial name
- NCT04164277
- Testing
- Caregiver Component., Caregiver-Preschooler Learning., Center-based Preschooler Component.
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Pediatric Obesity, Overweight and Obesity
Pediatric Obesity Treatment in a Safety Net Clinic: Piloting the Step by Step Program
Obesity treatment interventions have been studied in pediatric primary care offices and are often conducted in low-income and minority populations, and pediatric obesity clinics.
- Trial name
- NCT04297228
- Testing
- Step by Step: A Family-Centered Healthy Lifestyle Intervention
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Community Volunteers In Medicine
Childhood Obesity Prevention
Digitally Delivered Child Obesity Prevention for Parents in Home Visiting Programs
The goal of this clinical trial is to determine feasibility and acceptability of a digitally-based obesity prevention intervention for mothers of infants participating in a home visitation program.
- Trial name
- NCT07230808
- Testing
- digital intervention + home visiting curriculum, Home visiting curriculum
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators
This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder
The goal of this observational study is to evaluate cardiorespiratory and muscular fitness in children with obesity, with and without autism spectrum disorder (ASD), and examine how fitness relates to body measurements, body…
- Conditions
- Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators, Cardiometabolic Risk Factors, Metabolic Syndrome
- Trial name
- ROACH (NCT07804680)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Virginia
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