Clinical trials: Observation
Congenital Fibrinogen Deficiency
Safety and Efficacy of Fibryga in Congenital Fibrinogen Deficiency
Open-label, Uncontrolled, Multicenter Observational Study on the Safety and Efficacy of Fibryga in Congenital Fibrinogen Deficiency
- Trial name
- NCT03793426
- Testing
- Fibryga
- Where
- 4 sites in Czechia, Germany
- Volunteers
- 7 people
- Sponsor
- Octapharma
Colorectal Neoplasms Malignant
The COLON Study: Colorectal Cancer Cohort
The main aim of this observational, prospective cohort study is to assess associations of diet and other lifestyle factors with colorectal cancer recurrence, survival and quality of life.
- Trial name
- COLON (NCT03191110)
- Testing
- No intervention: observational study
- Where
- 11 sites in Netherlands
- Volunteers
- 2,000 people
- Sponsor
- Wageningen University
Rheumatoid Arthritis, Spondyloarthritis
Pregnancy and Medically Assisted Conception in Rare Diseases
Rare diseases frequently affect women of childbearing age. Pregnancy in these women has become less rare, but remains associated with high levels of complications.
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Psoriatic Arthritis, Systemic Lupus Erythematosus
- Trial name
- EGR2 (NCT02450396)
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma
Analysis of Exhaled Breath by Biosensors in Adults With Asthma
The aim of this study is to investigate the pattern of organic volatile compounds (VOCs) in the exhaled breath detected by biosensors in adults with persistent mild asthma.
- Trial name
- NCT00819676
- Testing
- analysis of exhaled breath by biosensors, measurement of exhaled nitric oxide
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Contraception
European Active Surveillance Study Comparing Regimens of Administration in Combined Hormonal Contraception
This study compares the risks of short- and long-term use of FC Patch Low with levonorgestrel-containing combined oral contraceptives (COC-LNG) in a study population representative of the actual users of the individual…
- Trial name
- EURAS-CORA (NCT02577913)
- Where
- Germany
- Volunteers
- 2,281 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Multiple System Atrophy
Long-term Follow-up of Phase 1 Clinical Trial of CS10BR05(CS10BR05-MSA101)
The study purpose is conducting follow-up surveillance for the incidence of adverse events and efficacy of subjects participated in phase 1 trial to evaluate the safety and tolerability of autologous bone marrow-derived…
- Trial name
- NCT04495582
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Corestemchemon, Inc.
Tuberculosis
Latent Tuberculosis Infection in Bone Marrow Transplant Recipients
The aim of this study is to estimate the usefulness of a T cell-based assay (i.e. Quantiferon-Gold In-Tube assay) for diagnosis of latent tuberculosis infection (LTBI) in bone marrow transplant recipients.
- Trial name
- NCT01021124
- Where
- South Korea
- Volunteers
- 409 people
- Sponsor
- Asan Medical Center
Rhinitis, Allergic, Seasonal, Rhinitis, Allergic, Perennial
Observation of Side Effects and Effectiveness of Desloratadine (Aerius) Syrup in Filipino Children (Study P05634)
The purpose of this study is to observe the side effects of desloratadine syrup and how effective it is in relieving symptoms of allergic rhinitis or hives in Filipino children.
- Conditions
- Rhinitis, Allergic, Seasonal, Rhinitis, Allergic, Perennial, Urticaria
- Trial name
- NCT00761527
- Testing
- Desloratadine Syrup
- Volunteers
- 2,980 people
- Sponsor
- Organon and Co
Obesity, Bariatrics
Comparing the Benefits and Harms of Three Types of Weight Loss Surgery -- The PCORnet® Bariatric Study
The main goal of this research project is to conduct a comparative effectiveness research study involving existing data in the PCORnet Common Data Model to provide accurate estimates of the 1-, 3-, and 5-year benefits and risks…
- Conditions
- Obesity, Bariatrics, Body Weight, Diabetes Mellitus
- Trial name
- PBS (NCT02741674)
- Testing
- Roux-en-y gastric bypass (RYGB) - historical, Adjustable gastric banding (AGB) - historical, Sleeve gastrectomy (SG) - historical
- Volunteers
- 65,093 people
- Sponsor
- Kaiser Permanente
Cerebral Arteries, Dissection
Prospective Observation for Serial Changes in Acute Intracranial Artery Dissection Using HR-MRI
Intracranial artery disease has been more detected with development of HR-MR. HR-MR can depict vascular wall directly and give us more information beyond the pre-existing imaging modalities such as digital subtraction…
- Trial name
- NCT03213470
- Testing
- magnetic resonance imaging
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
Influenza A (H1N1)
Observational Safety and Effectiveness Study of Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Egg Derived Vaccine
This observational study will evaluate the safety and effectiveness following administration of adjuvanted Swine Origin A (H1N1) Pandemic Subunit Egg Derived Vaccine through both an ad hoc active monitoring system and a passive…
- Trial name
- NCT01101074
- Testing
- This is non-intervention observational study
- Where
- Italy
- Volunteers
- 135,469 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Hospitalized Children
Relationship Between Adverse Drug Reactions and Unlicensed/ Off-label Drug Use in Hospitalized Children
Medications are the most commonly used clinical intervention and complications associated with their use are one of the most common causes of adverse events in health care.
- Trial name
- EREMI (NCT02852590)
- Where
- France
- Volunteers
- 6,227 people
- Sponsor
- Hospices Civils de Lyon
Cardiovascular Diseases, Vascular Disease
An Observational Registry Using Drug Eluting Stents (DES) in Patients in a Real-World Setting (DEScover Registry).
The DEScover Registry is designed to observe the results of using Drug Eluting Stents (DES) in patients in a real-world setting.
- Conditions
- Cardiovascular Diseases, Vascular Disease, Arterial Occlusive Disease, Arteriosclerosis
- Trial name
- DESCOVER (NCT00489320)
- Testing
- Cypher Stent
- Where
- United States
- Volunteers
- 7,759 people
- Sponsor
- Cordis US Corp.
Hemophilia A
A 48-Month Study to Evaluate Long-Term Effectiveness of Elocta on Joint Health
This is a 48-month observational, prospective, multicentre study. The overall aim of the study is to evaluate the long-term effectiveness of Elocta treatment on joint health in patients treated prophylactically with Elocta in a…
- Trial name
- A-MORE (NCT04293523)
- Testing
- ELOCTA
- Where
- 53 sites in Czechia, Estonia and 12 more
- Volunteers
- 427 people
- Sponsor
- Swedish Orphan Biovitrum
Exudative Age-Related Macular Degeneration
Monocentric Retrospective Observational Study on Patients With Macular Degeneration
Main Objective: The main objective of this retrospective observational study was to describe the evolution of visual acuity measured on ETDRS (Early Treatment Diabetic Retinopathy Study) scale, for patients with exudative…
- Trial name
- ELOUAN (NCT02089503)
- Testing
- intravitreal injections of Lucentis
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Pyruvate Kinase Deficiency
Pyruvate Kinase Deficiency Epidemiological Study (PIECE)
Pyruvate kinase deficiency (PKD) is the most common red cell glycolytic enzyme defect causing hereditary non-spherocytic hemolytic anemia, caused by mutations in the PKLR gene.
- Trial name
- PIECE (NCT03866590)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- CENTOGENE GmbH Rostock
Inflammatory Bowel Diseases (IBD)
Epidemiological Evaluation Of Chronic Kidney Disease In Pediatric Patients With Inflammatory Bowel Disease
This multicenter observational cross-sectional study aims to evaluate the prevalence of chronic kidney disease (CKD) in pediatric patients with inflammatory bowel disease (IBD) and to compare it with a control group without IBD.
- Trial name
- KIBD (NCT07670988)
- Testing
- Clinical and Laboratory Data Collection
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Cardiovascular Disease, Cerebrovascular Disorders
Safety FollowUp Study Of Cardiovascular Events In Subjects Who Participated In Selected Torcetrapib/Atorvastatin Studies
An observational safety follow up trial will be conducted to monitor the occurrence of cardiovascular events and all cause mortality in subjects who participated in selected torcetrapib/atorvastatin Phase 1, 2, and 3 clinical…
- Trial name
- NCT00452842
- Where
- United States
- Volunteers
- 26,784 people
- Sponsor
- Pfizer
C-KIT Mutation
A Study of c-Kit Mutation as MRD in Acute Myeloid Leukemia
C-Kit is involved in an essential pathway of disease occurrence and is closely related to the poor prognosis of patients. However, the clinical significance of c-Kit mutation as molecular MRD monitoring is still unclear.
- Trial name
- NCT06116318
- Where
- China
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Hemiplegia, Digital Mirror
Digital Mirror Versus Action Observation Therapy on Upper Limb Function and Grip Strength in Children With Hemiplegia
Statement of problem: 1. Does the digital mirror therapy has effect on upper limb function and grip strength in children with hemiplegia ? 2.
- Conditions
- Hemiplegia, Digital Mirror, Action Observation Therapy
- Trial name
- NCT07654595
- Testing
- digital mirror therapy, action observation therapy, designed occupational therapy program
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
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