Clinical trials: Obsessive Compulsive Disorder (OCD)
Behavioral Activation, Major Depressive Disorder
Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation
The purpose of this study is to identify and validate a panel of genetic markers associated with selective serotonin reuptake inhibitors (SSRI)-induced behavioural activation in children and youth with major depressive disorder…
- Conditions
- Behavioral Activation, Major Depressive Disorder, Anxiety Disorders, Antidepressant Drug Adverse Reaction
- Trial name
- PGx-SImBA (NCT06763081)
- Testing
- Not applicable- observational study
- Where
- 2 sites in Canada
- Volunteers
- 160 people
- Sponsor
- University of Manitoba
Obessive-Compulsive Disorder
Efficacy and Influencing Factors of Mindfulness-Based Exposure Group Therapy for OCD
Obessive-Compulsive Disorder (OCD) is frequently treatment-refractory and imposes a substantial burden on affected individuals. Although Exposure and Response Prevention (ERP) is widely regarded as the first-line intervention…
- Trial name
- NCT07484750
- Testing
- mindfulness based exposure therapy, Treatment as Usual (TAU)
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Shanghai Mental Health Center
Prader-Willi Syndrome, Obesity
Effects of Transcranial Direct Current Stimulation (tDCS) on Individuals With Prader-Willi Syndrome
Prader-Willi Syndrome (PWS) is a multisystemic genetic disease characterized by hypotonia, mental retardation, hyperphagia, and uncontrollable hunger due to hypothalamic dysfunction, caused by dysregulation of genes located in…
- Conditions
- Prader-Willi Syndrome, Obesity, Depressive Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT03324906
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Obsessive Compulsive Disorder
Attention Training for Childhood Obsessive Compulsive Disorder
Voluntary and involuntary attention processes are thought to play an important role in the development and maintenance of anxiety disorders including OCD.
- Trial name
- AMP-OCD (NCT02114918)
- Testing
- Attention Modification Program, Attention Control Condition
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder
Internet-delivered CBT for Adolescents With Obsessive-Compulsive Disorder - a Pilot Study
The main goal of this trial is to study the feasibility and effectiveness of internet-delivered cognitive behavior therapy for adolescents with obsessive-compulsive disorder.
- Trial name
- NCT01809990
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Eva Serlachius
High Risk, Depression / Major Depressive Disorder
Tracking Risk in Adolescents and Children for Early Identification of Common Mental Disorders
This prospective observational cohort study will enroll approximately 200 children and adolescents aged 7-17 years who are at elevated risk for common mental disorders, including depressive disorders, anxiety disorders, and…
- Conditions
- High Risk, Depression / Major Depressive Disorder, Anxiety Disease, Obsessive - Compulsive Disorder
- Trial name
- TRACE (NCT07744490)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Mental Health Center
Obsessive-Compulsive Disorder
Family Focused Treatment of Pediatric Obsessive Compulsive Disorder
Pediatric obsessive compulsive disorder (OCD) is a chronic, impairing condition that accrues significant concurrent and long-term risk to affected youth (Piacentini et al. 2003; Pine et al. 1998).
- Trial name
- PFIT (NCT01409642)
- Testing
- Individual Child CBT, Positive Family Interaction Therapy
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder, Obsessive-Compulsive Disorder in Children
SPACE: a Parent-based Treatment for Pediatric OCD
This study will investigate the parent-based treatment SPACE: Supportive Parenting for Anxious Childhood Emotions. The aim of this study is to investigate whether SPACE is effective in reducing family accommodation (FA) and OCD…
- Conditions
- Obsessive-Compulsive Disorder, Obsessive-Compulsive Disorder in Children, Obsessive-Compulsive Disorder in Adolescence, Anxiety Disorders and Symptoms
- Trial name
- NCT06356090
- Testing
- Supportive Parenting for Anxious Childhood Emotions (SPACE)
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Chaim Huijser
Anxiety Disorders, Obsessive-Compulsive Disorder
A Trial of Parent-coached Exposure Therapy for Children With Anxiety Disorders and OCD
The purpose of this study is to examine the effectiveness of parent coached exposure therapy (PCET) and standard cognitive behavioral therapy (CBT) in treating childhood anxiety disorders and obsessive compulsive disorder (OCD).
- Trial name
- NCT05777161
- Testing
- Parent Coached Exposure Therapy - Individualized, Cognitive Behavior Therapy, Parent Coached Exposure Therapy - Group (removed from study)
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Mayo Clinic
Autism, Asperger's Syndrome
Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
Due to the considerable prevalence of anxiety in youth with autism spectrum disorders, this study seeks to establish the efficacy of a modified cognitive behavioral therapy protocol in 50 adolescents versus other available…
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01563003
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obsessive Compulsive Disorder
Fluvoxamine Maleate in the Treatment of Obsessive-Compulsive Disorder: A Post-marketing Clinical Study in Children and Adolescents
This study is to verify the efficacy of fluvoxamine maleate given for 10 weeks in treatment of children and adolescents with obsessive-compulsive disorder
- Trial name
- NCT00352768
- Testing
- Fluvoxamine maleate
- Where
- 11 sites in Japan
- Volunteers
- 20 people
- Sponsor
- Solvay Pharmaceuticals
Obsessive Compulsive Disorder
CBT for Pediatric OCD: Community Training Pilot
This study examines a training program for clinicians who work in mental health clinics that serve children with OCD. We will provide clinician training in conducting exposure-based treatments for children with OCD.
- Trial name
- NCT02202915
- Testing
- Behavioral Checklist
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Rhode Island Hospital
Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD)
Stepped Care Treatment for Anxiety Resilience
Childhood anxiety disorders (CAD) are common and impairing. Family based cognitive behavioral therapy (CBT) is efficacious in treating CAD.
- Conditions
- Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Separation Anxiety Disorder, Specific Phobia
- Trial name
- STAR (NCT07228143)
- Testing
- Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Andrew Wiese
Anorexia Nervosa, Obsessive-compulsive Disorder
Neural Links Between OCD and Anorexia
Individuals with anorexia nervosa (AN) have long been observed to demonstrate symptoms in common with obsessive-compulsive disorder (OCD), in particular, an obsessive fear of normal weight leading to dangerous food restriction…
- Trial name
- NCT02085057
- Testing
- Functional Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder in Children
Quality Assessment in Exposure Therapy
This project will test a measure of treatment quality, Exposure Guide, for therapists using exposure therapy for youths and young adults with anxiety or OCD.
- Trial name
- NCT03182101
- Testing
- Exposure Therapy
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Bradley Hospital
Obsessive-Compulsive Disorder
Developing Adaptive Treatment Strategies for Children and Adolescents With Obsessive-compulsive Disorder.
Obsessive-compulsive disorder affects approximately 2% of the population, frequently has its onset during childhood or adolescence and is potentially incapacitating.
- Trial name
- SMART (NCT01148316)
- Testing
- fluoxetine, Group cognitive-behavioral therapy
- Where
- Brazil
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Roseli Shavitt
ADHD, Obsessive Compulsive Disorder (OCD)
Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)
Background: Attention deficit hyperactivity disorder (ADHD) is common in children. It can cause problems with attention and the ability to control actions and impulses.
- Conditions
- ADHD, Obsessive Compulsive Disorder (OCD), Healthy Volunteer
- Trial name
- NCT07566468
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Cognitive Behavioral Therapy, Autism Spectrum Disorder
Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety
This study implements a parent-led, flexible, individually-tailored cognitive-behavioral intervention for children with ASD and anxiety.
- Conditions
- Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- NCT03720795
- Testing
- Stepped Care CBT
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Baylor College of Medicine
Anorexia Nervosa
Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation
Transcranial Magnetic Stimulation (TMS) is approved by the Food and Drug Administration (FDA) for the treatment of refractory Major Depressive Disorder (MDD) and obsessive-compulsive disorder (OCD).
- Trial name
- NCT06138782
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Obsessive-Compulsive Disorder
Short and Intensive Treatment of Children and Adolescents With Obsessive-Compulsive Disorder
Obsessive-compulsive disorders are very damaging illnesses; they can already appear in childhood and adolescence and become extremely chronic.
- Trial name
- NCT04730011
- Testing
- Short and Intensive Treatment
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Susanne Walitza