Clinical trials: Obsessive-Compulsive Symptoms
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)
Background: PANS is an illness that comes on suddenly in children. The full name is Pediatric Acute-Onset Neuropsychiatric Syndrome. It can cause sudden obsessive-compulsive behaviors.
- Trial name
- NCT03507218
- Where
- 8 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Obsessive Compulsive Disorder
Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD
This study will examine the feasibility and potential efficacy of augmenting SRIs with minocycline. The study will assess whether the addition of minocycline leads to measurable changes in striatal glutamate (Glu) levels.
- Trial name
- NCT01695291
- Testing
- Minocycline
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- New York State Psychiatric Institute
Prader-Willi Syndrome, Obesity
Effects of Transcranial Direct Current Stimulation (tDCS) on Individuals With Prader-Willi Syndrome
Prader-Willi Syndrome (PWS) is a multisystemic genetic disease characterized by hypotonia, mental retardation, hyperphagia, and uncontrollable hunger due to hypothalamic dysfunction, caused by dysregulation of genes located in…
- Conditions
- Prader-Willi Syndrome, Obesity, Depressive Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT03324906
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Obsessive Compulsive Behavior
Digital OC Training in Children and Adolescents
The project is an interventional trial that compares digital training programs with varying levels of therapeutic contact. All participating children and adolescents will receive a digital training program following a thorough…
- Trial name
- DOT-Y (NCT07864675)
- Testing
- Digital behavioral training
- Volunteers
- 20 people
- Sponsor
- Aarhus University Hospital
Obsessive-compulsive Disorder, Social Phobia
Brief Behavioral Treatment for Anxiety in Young Children
Behaviorally and cognitive-behaviorally based therapeutic techniques (BT; CBT) that incorporate exposure therapy useful for treatment of anxiety disorders among typically developing children.
- Conditions
- Obsessive-compulsive Disorder, Social Phobia, Generalized Anxiety Disorder, Specific Phobia
- Trial name
- PLET (NCT02051192)
- Testing
- Parent-Led Exposure Therapy, Treatment As Usual
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of South Florida
Tourette Syndrome, Obsessive Compulsive Disorder
Developmental Phenomenology of Obsessive Compulsive Disorder and Tourette Syndrome in Children and Adolescents
OBJECTIVES: I. Characterize the natural history, associated features, and severity of symptoms of obsessive compulsive disorder and Tourette syndrome in children and adolescents. II.
- Trial name
- NCT00004324
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Center for Research Resources (NCRR)
Parkinson Disease, Dystonia
Physiological Brain Atlas Development
Enrollment of candidates undergoing a deep brain stimulator (DBS) implant.
- Conditions
- Parkinson Disease, Dystonia, Tremors, Obsessive Compulsive Disorder
- Trial name
- NCT01210534
- Testing
- No intervention
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- Ohio State University
Obsessive-compulsive Disorder With Acute Onset, PANDAS
PANS - A Detailed Study of the Patients, Their Symptoms, Biomarkers and Treatment Offered in a Scandinavian Cohort
Background: Obsessive-compulsive disorder (OCD) is considered one of the most debilitating of the psychiatric illnesses, yet much remains unclear regarding causes and cures.
- Conditions
- Obsessive-compulsive Disorder With Acute Onset, PANDAS, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections, Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
- Trial name
- NCT02190292
- Where
- Sweden
- Volunteers
- 185 people
- Sponsor
- Karolinska Institutet
Tourette's Disorder
Omega-3 Fatty Acids in Tourette's Disorder
This study examines the safety and efficacy of omega-3 fatty acids (fish oil) for the treatment of Tourette's Disorder.
- Trial name
- NCT01315327
- Testing
- Omega-3 Fatty Acids, Olive oil
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health
PANS, PANDAS
Antibiotic Treatment Trial for the PANDAS/PANS Phenotype
The purpose of this research study is to know if the antibiotic azithromycin, an antibiotic approved by the U.S. Food and Drug Administration (FDA) for treating infections, improves symptom severity in children with sudden and…
- Conditions
- PANS, PANDAS, Obsessive Compulsive Disorder (OCD)
- Trial name
- AZT (NCT01617083)
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of South Florida
Obsessive-compulsive Disorders and Symptoms in Children
Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children
This study will use magnetic resonance imaging (MRI) to assess the function and structure of overlapping task control circuits in children with a range of Obsessive-Compulsive symptoms (OCS).
- Trial name
- NCT03584945
- Testing
- Cognitive Behavioral Therapy, Community Referral as appropriate
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obsessive-Compulsive Disorder, Anxiety Disorders
Pharmacogenetics of Antidepressant-Induced Disinhibition
The purpose of this study is to identify pharmacogenetic profiles associated with selective serotonin reuptake inhibitors (SSRI)-induced behavioral disinhibition in children with Major depressive disorder (MDD), anxiety disorders…
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Major Depressive Disorder, Antidepressant Drug Adverse Reaction
- Trial name
- PGx-AID (NCT03953014)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Calgary
Anorexia Nervosa
Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation
Transcranial Magnetic Stimulation (TMS) is approved by the Food and Drug Administration (FDA) for the treatment of refractory Major Depressive Disorder (MDD) and obsessive-compulsive disorder (OCD).
- Trial name
- NCT06138782
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Obsessive-Compulsive Disorder, Anxiety Disorders
Improving Access to Child Anxiety Treatment
There is strong evidence that cognitive behavioral therapy (CBT) with exposure is the preferred treatment for youth with anxiety disorders, but outpatient services that provide this type of treatment are limited.
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Pediatric Disorder, Anxiety
- Trial name
- IMPACT (NCT03528109)
- Testing
- Exposure Therapy
- Where
- United States
- Volunteers
- 379 people
- Sponsor
- Bradley Hospital
Anxiety Disorders, Depression
Pharmacogenomics of Antidepressant Response in Children and Adolescents
This study will identify variations in genes that may be involved in the development of suicidal events or certain behaviors in youth who are exposed to antidepressant medications.
- Conditions
- Anxiety Disorders, Depression, Eating Disorders, Obsessive-Compulsive Disorder
- Trial name
- PARCA (NCT00516932)
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Duke University
Anxiety Disorders, Depression
Unified Protocol for Adolescents (UP-A) Change Processes
The purpose of this protocol is to employ single case analytic strategies, including a multiple baseline design and novel modeling techniques to identify changes in cross-cutting features of emotional disorders as well as…
- Conditions
- Anxiety Disorders, Depression, Obsessive-Compulsive Disorder, Adolescent - Emotional Problem
- Trial name
- NCT03102008
- Testing
- Unified Protocol for Emotional Disorders in Adolescents (UP-A)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders
Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness.
- Conditions
- Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety
- Trial name
- IMPACT-RI (NCT06934525)
- Testing
- Team-delivered, exposure-based CBT
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Bradley Hospital
Anorexia Nervosa
Obsessive-compulsive Symptoms in Children and Adolescents With Anorexia Nervosa
The purpose of this study is to determine obsessive-compulsive symptoms and BMI changes in children and adolescents with anorexia nervosa and find out whether there is a group-level correlation between the two.
- Trial name
- NCT04770662
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universitair Ziekenhuis Brussel
PANDAS, Anxiety Disorder
Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS
This project aims to rigorously evaluate a potential treatment for inflammation-related Obsessive-Compulsive Disorder (OCD) symptoms in children.
- Conditions
- PANDAS, Anxiety Disorder, Autoimmune Diseases, Obsessive-Compulsive Disorder
- Trial name
- NCT04015596
- Testing
- Naproxen Sodium
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital