Clinical trials: Obsessive-compulsive Disorder
Obsessive-Compulsive Disorder
Internet-delivered CBT for Adolescents With OCD: A Randomized Controlled Study
The effect of Internet-delivered Cognitive Behavior Therapy (ICBT) on adolescents (12 to 17 years) with Obsessive-Compulsive Disorder is studied. Participants are randomized to either ICBT or a no-treatment condition.
- Trial name
- BiPOCD (NCT02191631)
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Karolinska Institutet
Obsessive - Compulsive Disorder
Efficacy and Underlying Mechanisms of Group-Based Natural Psychotherapy for Anxiety Disorder
This study aims to preliminarily explore the intervention effect and feasibility of group natural psychotherapy (a new Eastern culture-based psychotherapy method) for patients with anxiety disorder through a randomized controlled…
- Trial name
- NCT07518264
- Testing
- Group-based Natural Psychotherapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing HuiLongGuan Hospital
Obsessive-Compulsive Disorder in Children, Obsessive-Compulsive Disorder in Adolescence
Treatment Effects of Family Based Cognitive Therapy in Children and Adolescents With Obsessive Compulsive Disorder
To investigate the benefits and harms, and the neural and neurocognitive mediators of treatment response, in family-based cognitive behavioural therapy versus family-based psychoeducation and relaxation training in children and…
- Trial name
- TECTO (NCT03595098)
- Testing
- Family Based Cognitive Behavioural Therapy, Family Based Psychoeducation/Relaxation Training
- Where
- Denmark
- Volunteers
- 128 people
- Sponsor
- Anne Katrine Pagsberg
Obsessive Compulsive Disorder (OCD)
NAC for Treatment-Resistant OCD and Other Related Disorders
This is a randomized, double-blind, placebo-controlled study investigating N-acetylcysteine (NAC) as an augmentation therapy for individuals with treatment-resistant obsessive-compulsive disorder (TR-OCD), studied within a…
- Trial name
- NCT06956157
- Testing
- N-Acetylcysteine Tablets
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy
Cognitive Behavioral Group Treatment for Obsessive-compulsive Disorder in Youth
Obsessive-compulsive disorder (OCD) is a debilitating disorder characterized by unwanted intrusive thoughts and disrupting repetitive rituals.
- Conditions
- Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy, Adolescent
- Trial name
- NCT04891367
- Testing
- Cognitive behavioral therapy
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Aarhus University Hospital
Psychotherapy Intervention Evaluation
iCBT for Children and Adolescents With Obsessive-compulsive Disorder II
Internet-based psychotherapy for children and adolescents with obsessive-compulsive symptoms and an age of 6 to 18 years. Sessions are verified with teleconferencing with an psychotherapist, children and their parents.
- Trial name
- NCT05037344
- Testing
- Cognitive-behavioral psychotherapy
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Cognitive Behavioral Therapy, Autism Spectrum Disorder
Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD
This study implements an anxiety-focused, parent-led, therapist-assisted cognitive behavioral teletherapy for parents of youth with ASD and anxiety.
- Conditions
- Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- NCT04111874
- Testing
- Cognitive Behavioral Teletherapy LTA, Cognitive Behavioral Teletherapy STA
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
A Wearable AI Feedback Tool for Pediatric OCD
To test the feasibility of implementing digitally enhanced psychotherapy and research in a community child and adolescent mental health center including the acceptability of the digital technology to patients, parents and…
- Trial name
- NCT05064527
- Testing
- wearable biosensor, Treatment as usual (TAU), Exposure and response prevention (ERP)
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Obsessive Compulsive Disorder OCD
Impact of Attention on Obsessive Thoughts Through THOUGHT
Impact of attention on obsessive through the THOUGHT-scale (Troublesome Human Obsessions and Untargeted General Habitual Thoughts Scale): a description of the content of thoughts according to the level of attention demanded by…
- Trial name
- THOUGHTS (NCT05944172)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obsessive-Compulsive Disorder
Treatment of Obsessive-Compulsive Disorder (OCD) in Children
The purpose of this study is to compare 3 treatments for children with OCD: medication (sertraline, SER) alone vs OCD-specific therapy (Cognitive Behavior Therapy, CBT) vs medication plus therapy.
- Trial name
- NCT00000384
- Testing
- Cognitive Behavior Therapy, Educational Support, Sertraline
- Where
- 2 sites in United States
- Sponsor
- University of Pennsylvania
Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)
In this study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in modulating aberrant neurocognitive processes implicated in pediatric patients with obsessive compulsive disorder…
- Trial name
- NCT04548609
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Anxiety Disorders, Panic Disorder
Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis
Anxiety disorders are common disorders, which pose a major burden to society and the individual. An anxiety disorder may be treated with medication, in particular with antidepressants such as the selective serotonin reuptake…
- Conditions
- Anxiety Disorders, Panic Disorder, Obsessive-compulsive Disorder, Post-traumatic Stress Disorder
- Trial name
- NCT02476136
- Testing
- paroxetine, duloxetine, fluoxetine or venlafaxine
- Volunteers
- 8,800 people
- Sponsor
- prof. Peter de Jonge
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)
Background: PANS is an illness that comes on suddenly in children. The full name is Pediatric Acute-Onset Neuropsychiatric Syndrome. It can cause sudden obsessive-compulsive behaviors.
- Trial name
- NCT03507218
- Where
- 8 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive Compulsive Disorder
Attention Training for Childhood Obsessive Compulsive Disorder: An Open Case Series
Pediatric Obsessive Compulsive Disorder (OCD) is a chronic, impairing condition that accrues significant concurrent and long-term risk to affected youth.
- Trial name
- AMPOCD (NCT01708226)
- Testing
- Attention Modification Program
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder
Anxiety and obsessive-compulsive disorders are among the most common in children. Although cognitive behavioral therapy (CBT) is an effective and evidence-based treatment for such disorders, access to CBT is often limited.
- Conditions
- Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence
- Trial name
- NCT05967468
- Testing
- Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
Child and Adolescent OCD Outcomes From Exposure and Response Prevention Video Teletherapy Treatment
This is a naturalistic, observational study of children and adolescents with obsessive-compulsive disorder who were treated with exposure and response prevention via video teletherapy.
- Trial name
- NCT06466447
- Testing
- Exposure and response prevention therapy
- Where
- United States
- Volunteers
- 2,173 people
- Sponsor
- NOCD
Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder)
Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders
The goal of this clinical trial is to evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in reducing core symptoms of different psychiatric disorders using validated clinical scales.
- Conditions
- Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder), Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- Transcranial (NCT07452835)
- Testing
- tDCS Parameters
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Menoufia University
Pediatric Acute-Onset Neuropsychiatric Syndrome, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections
A Study to Evaluate the Benefit of Octagam 5%® in Subjects With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
This study will evaluate the use of intravenous immunoglobulins (IVIG) at a dose of 1g/Kg/body weight given every three weeks for 6 infusions in pediatric subjects ages 4 - 16 years with moderate to severe PANS.
- Trial name
- PANS (NCT03348618)
- Testing
- IVIG
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- IMMUNOe Research Centers
Obsessive-Compulsive Disorder
An eHealth Intervention for Obsessive Compulsive Disorder in Youth With Autism Spectrum Disorder
This study is a feasibility study of Internet-delivered CBT for OCD in children and adolescents (7-17 years) with comorbid Autism Spectrum Disorder.
- Trial name
- NCT03473080
- Testing
- Internet CBT
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Karolinska Institutet
Obsessive-compulsive Disorder
Clinical Outcomes in Pediatric Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder (OCD) is a common neuropsychiatric illness beginning in childhood. Effective OCD treatments include cognitive-behaviour therapy (CBT) and medications but access to treatment is difficult and does not…
- Trial name
- NCT01635569
- Testing
- Group-based family cognitive-behavioural therapy, Waitlist
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- University of British Columbia