Clinical trials: Obsessive-compulsive Disorder
Obsessive - Compulsive Disorder
Effect of a Family-Based CBT Self-Help Intervention for Adolescents With OCD
The goal of this clinical trial is to learn if self-help book can be used to treat obsessive-compulsive disorder (OCD) in adolescents aged 10 to 17.
- Trial name
- NCT06942494
- Testing
- conventional medical treatment (TAU), Family-Based Self-help Book for Adolescents with Obsessive-Compulsive Disorder
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Anorexia Nervosa
Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation
Transcranial Magnetic Stimulation (TMS) is approved by the Food and Drug Administration (FDA) for the treatment of refractory Major Depressive Disorder (MDD) and obsessive-compulsive disorder (OCD).
- Trial name
- NCT06138782
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Mental Disorder Diagnosed in Childhood, Obsessive Compulsive Disorder
Preventive Measures for Childhood-Onset Obsessive-Compulsive Disorder and Tic Disorders (PANDAS Subgroup)
A subgroup of patients with childhood-onset obsessive-compulsive disorder (OCD) and/or tic disorders has been identified who share a common clinical course characterized by dramatic onset and symptom exacerbations following group…
- Conditions
- Mental Disorder Diagnosed in Childhood, Obsessive Compulsive Disorder, Streptococcal Infection, Tic Disorder
- Trial name
- NCT00001359
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive-Compulsive Disorder
Ketamine Treatment for Pediatric-Refractory Obsessive-Compulsive Disorder (OCD)
This pilot study is proposed to determine the acceptability, feasibility and potential efficacy of ketamine, a medication that modulates glutamate in the brain, as a rapid treatment for obsessive-compulsive disorder (OCD)…
- Trial name
- NCT02422290
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- New York State Psychiatric Institute
Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders
Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness.
- Conditions
- Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety
- Trial name
- IMPACT-RI (NCT06934525)
- Testing
- Team-delivered, exposure-based CBT
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Bradley Hospital
Childhood Obsessive-Compulsive Disorder, Autism Spectrum Disorders
A Magnetic Resonance Spectroscopic Examination of Children and Adolescents Taking Riluzole for Obsessive-Compulsive Disorder
Background: Obsessive-compulsive disorder (OCD) is a common childhood disorder that often does not respond to standard treatments.
- Trial name
- NCT01019967
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Obessive-Compulsive Disorder
Efficacy and Influencing Factors of Mindfulness-Based Exposure Group Therapy for OCD
Obessive-Compulsive Disorder (OCD) is frequently treatment-refractory and imposes a substantial burden on affected individuals. Although Exposure and Response Prevention (ERP) is widely regarded as the first-line intervention…
- Trial name
- NCT07484750
- Testing
- mindfulness based exposure therapy, Treatment as Usual (TAU)
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Shanghai Mental Health Center
Obsessive-Compulsive Disorder, Social Anxiety Disorder
Neurobiological Markers of Treatment Response for Anxiety and OCD
Obsessive-compulsive disorder (OCD) and anxiety disorders are common and debilitating conditions which are often chronic when treatment is not provided.
- Conditions
- Obsessive-Compulsive Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT05663489
- Testing
- Bergen 4-Day Treatment (B4DT)
- Where
- Norway
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder
Anxiety and obsessive-compulsive disorders are among the most common in children. Although cognitive behavioral therapy (CBT) is an effective and evidence-based treatment for such disorders, access to CBT is often limited.
- Conditions
- Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence
- Trial name
- NCT05967468
- Testing
- Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Substance Use, Deliberate Self-harm
Evaluation of a Brief Surf the Urge Intervention
The purpose of this study is to evaluate the effectiveness of a brief "Surf the Urge" intervention to reduce adolescent and young adult (i.e., 14 to 24 years old) urge-related behaviors.
- Conditions
- Substance Use, Deliberate Self-harm, Trichotillomania, Aggression
- Trial name
- SUBMI (NCT02771886)
- Testing
- Surf the Urge
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kimberly N Schubert
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Obsessive-Compulsive Disorder in Children
Cognitive Control Targets for the Treatment of Obsessive Compulsive Disorder in Young Children
This study aims to examine the effects of a game-like program called cognitive control training (CT) for children with obsessive compulsive disorder (OCD).
- Trial name
- NCT06102941
- Testing
- Cognitive Control Training (CT)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Anorexia Nervosa
Obsessive-compulsive Symptoms in Children and Adolescents With Anorexia Nervosa
The purpose of this study is to determine obsessive-compulsive symptoms and BMI changes in children and adolescents with anorexia nervosa and find out whether there is a group-level correlation between the two.
- Trial name
- NCT04770662
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universitair Ziekenhuis Brussel
Obsessive-Compulsive Disorder
Initial Development and Dissemination of OC-Go
The clinical component of Phase I application development examines the clinical utility, feasibility, and functionality of the OC-Go application via an 8-month pilot trial consisting of 50 standard CBT sessions augmented with…
- Trial name
- OC-GoPhaseI (NCT03126305)
- Testing
- OC-Go
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder
Clinical Outcomes From NOCD Treatment of Obsessive-Compulsive Disorder Using Exposure and Response Prevention
This is a naturalistic, observational study of individuals with obsessive-compulsive disorder who were treated with exposure and response prevention via video teletherapy, augmented with between-session support with text…
- Trial name
- NCT04701372
- Testing
- Exposure and response prevention therapy
- Where
- United States
- Volunteers
- 2,069 people
- Sponsor
- NOCD
OCD
Therapist Guided, Parent-led, Cognitive Behavioural Therapy (CBT) for Preadolescent Children With Obsessive Compulsive Disorder (OCD)
This preliminary study aims to examine the outcomes from a therapist guided, parent-led, CBT treatment for preadolescent children (aged 5 to 12 years old) with OCD. Specifically, this study aims to: 1.
- Trial name
- NCT05981690
- Testing
- Therapist guided, parent-led CBT for preadolescent children with OCD
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Reading
Trichotillomania, Hair Pulling Disorder
Milk Thistle in Trichotillomania in Children and Adults
The goal of the proposed study is to evaluate the efficacy and safety of silymarin (milk thistle) in children and adults with trichotillomania.
- Trial name
- NCT02473913
- Testing
- Milk Thistle
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Chicago
Obsessive Compulsive Disorder
Treatment Youth With Obsessive-Compulsive Disorder
Although research suggests that patients with obsessive-compulsive disorder (OCD) exhibit specific deficits in their high cognitive processes, it is still unknown how these deficits relate to the clinical symptoms of the…
- Trial name
- NCT00708240
- Testing
- Escitalopram
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Obsessive-Compulsive Disorder
Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation
This is a pilot study to examine the tolerability, safety and early efficacy of two forms of transcranial magnetic stimulation (TMS) for treating adolescents with Obsessive Compulsive Disorder (OCD) who have experienced limited…
- Trial name
- NCT07065669
- Testing
- Dorsal medial Prefrontal Cortex intermittent theta burst stimulation, cTBS to ROFC
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Obsessive-Compulsive Disorder
The Use of D-Cycloserine to Augment CBT for Pediatric OCD
Pediatric obsessive compulsive disorder (OCD) is a relatively common and often severe condition that can become chronic if untreated.
- Trial name
- DCS (NCT01687140)
- Testing
- D-Cycloserine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles