Clinical trials: Obsessive-compulsive Disorder
Obsessive-Compulsive Disorder in Adolescence
IBA Treatment in Adolescents With OCD
Adolescents with Obsessive-compulsive Disorder (OCD) have obsessions, compulsions or both. OCD is a severe psychiatric disorder, affecting many aspects of the lives of adolescents.
- Trial name
- NCT05547334
- Testing
- Inference Based Approach (IBA)
- Volunteers
- 8 people
- Sponsor
- Karakter Kinder- en Jeugdpsychiatrie
OCD
Light Therapy for Obsessive-compulsive Disorder (OCD)
The goal of this clinical trial is to test whether light therapy is effective for reducing symptoms in young adults with OCD and late bedtimes (1am or later).
- Trial name
- KLTO (NCT06720090)
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence
Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD
Anxiety disorders in children and adolescents are common and confer significant disability. Cognitive behavioral therapy (CBT) is the recommended treatment for youth with anxiety, yet many families cannot access CBT due to cost…
- Conditions
- Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder (GAD)
- Trial name
- ASTRO (NCT07024758)
- Testing
- Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Baylor College of Medicine
OCD
Effects of Sertraline on Brain Connectivity in Adolescents With OCD
The investigators will examine how treatment with sertraline for 12 weeks impacts frontal-striatal-thalamic circuitry (FSTC) in this OCD sample.
- Trial name
- NCT02797808
- Testing
- Sertraline, No Intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obsessive-Compulsive Disorder
Effectiveness of Sertraline and Cognitive Behavioral Therapy in Treating Pediatric Obsessive-Compulsive Disorder
This study measures the occurrence of certain side effects linked to antidepressant use and evaluates the effectiveness of the medication sertraline plus cognitive behavioral therapy to treat people with obsessive-compulsive…
- Trial name
- NCT00382291
- Testing
- Regular Titration, Slow Titration
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Obsessive-Compulsive Disorder
N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder
Pediatric Obsessive-Compulsive Disorder (OCD) affects 1-3% of children. The investigators currently have effective first-line interventions for pediatric OCD such as Cognitive Behavioral Therapy (CBT) and pharmacotherapy with…
- Trial name
- NCT01172275
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Yale University
Substance Use, Deliberate Self-harm
Evaluation of a Brief Surf the Urge Intervention
The purpose of this study is to evaluate the effectiveness of a brief "Surf the Urge" intervention to reduce adolescent and young adult (i.e., 14 to 24 years old) urge-related behaviors.
- Conditions
- Substance Use, Deliberate Self-harm, Trichotillomania, Aggression
- Trial name
- SUBMI (NCT02771886)
- Testing
- Surf the Urge
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kimberly N Schubert
Anxiety Disorders, Depression
Unified Protocol for Adolescents (UP-A) Change Processes
The purpose of this protocol is to employ single case analytic strategies, including a multiple baseline design and novel modeling techniques to identify changes in cross-cutting features of emotional disorders as well as…
- Conditions
- Anxiety Disorders, Depression, Obsessive-Compulsive Disorder, Adolescent - Emotional Problem
- Trial name
- NCT03102008
- Testing
- Unified Protocol for Emotional Disorders in Adolescents (UP-A)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Obsessive-compulsive Disorders and Symptoms in Children
Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children
This study will use magnetic resonance imaging (MRI) to assess the function and structure of overlapping task control circuits in children with a range of Obsessive-Compulsive symptoms (OCS).
- Trial name
- NCT03584945
- Testing
- Cognitive Behavioral Therapy, Community Referral as appropriate
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anxiety Disorders, Depression
Pharmacogenomics of Antidepressant Response in Children and Adolescents
This study will identify variations in genes that may be involved in the development of suicidal events or certain behaviors in youth who are exposed to antidepressant medications.
- Conditions
- Anxiety Disorders, Depression, Eating Disorders, Obsessive-Compulsive Disorder
- Trial name
- PARCA (NCT00516932)
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Duke University
Obsessive-Compulsive Disorder
The Use of D-Cycloserine to Augment CBT for Pediatric OCD
Pediatric obsessive compulsive disorder (OCD) is a relatively common and often severe condition that can become chronic if untreated.
- Trial name
- DCS (NCT01687140)
- Testing
- D-Cycloserine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder
Internet-delivered CBT for Adolescents With OCD: A Randomized Controlled Study
The effect of Internet-delivered Cognitive Behavior Therapy (ICBT) on adolescents (12 to 17 years) with Obsessive-Compulsive Disorder is studied. Participants are randomized to either ICBT or a no-treatment condition.
- Trial name
- BiPOCD (NCT02191631)
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder, Autism Spectrum Disorder
ICBT for OCD in Children With Autism
The purpose of this trial is to evaluate the clinical efficacy, the cost-effectiveness and the effect durability of a therapist-guided, internet-delivered cognitive-behavior therapy intervention for obsessive-compulsive disorder…
- Trial name
- NCT06582225
- Testing
- Internet-delivered exposure and response prevention (I-ERP), Internet-delivered stress management (I-SM)
- Where
- 3 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Karolinska Institutet
Obsessive Compulsive Disorder, Stepped Care Cognitive Behavioral Therapy
Stepped Care Cognitive Behavioral Therapy for Pediatric Obsessive Compulsive Disorder
The purpose of this research study is to determine how well children with OCD can be helped using therapy that requires less clinic visits.
- Trial name
- SC-CBT (NCT01981317)
- Testing
- Stepped Care Cognitive Behavioral Therapy, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of South Florida
Anxiety Disorders, Generalized Anxiety Disorder
Computerized Intervention Targeting the Error-Related Negativity and Balance N1 in Anxious Children
Anxiety disorders are the most common form of psychopathology, and frequently begin in childhood, resulting in lifelong impairment.
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT05503017
- Testing
- Psycho-social, computerized intervention targeting error sensitivity, Psycho-social, computerized intervention on healthy lifestyle choices
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Florida State University
Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders
Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness.
- Conditions
- Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety
- Trial name
- IMPACT-RI (NCT06934525)
- Testing
- Team-delivered, exposure-based CBT
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Bradley Hospital
Obsessive Compulsive Disorder
CBT for Pediatric OCD: Community Training Pilot
This study examines a training program for clinicians who work in mental health clinics that serve children with OCD. We will provide clinician training in conducting exposure-based treatments for children with OCD.
- Trial name
- NCT02202915
- Testing
- Behavioral Checklist
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Rhode Island Hospital
Autism, Asperger's Syndrome
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism spectrum disorders affect as many as 1 out of 150 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT01178385
- Testing
- Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety
Youth Mayo Clinic Anxiety Coach Randomized Controlled Trial
This research study aims to test the feasibility and effectiveness of using the Mayo Clinic Anxiety Coach smartphone app as an addition to traditional therapy for the treatment of anxiety disorders in youth, particularly those…
- Trial name
- NCT02205203
- Testing
- Mayo Clinic Anxiety Coach, Treatment as Usual
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Stephen Whiteside
Skin-Picking
Treating Skin Picking With Cognitive-Behavioral Protocol in Individual and Group Format.
Skin Picking Disorder (SPD) affects 1.4-5.4% of the general population. It has a high association with anxiety and depressive symptoms.
- Trial name
- NCT03182478
- Testing
- Rothbaum protocol in individual format, Rothbaum protocol in group format
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- Federal University of Health Science of Porto Alegre