Clinical trials: Obstetric Pain
Labor Pain
Combined Spinal/Epidural (CSE) Saline Duration/Spread
An attempt is being made to see if by injecting a set volume of sterile saline into the epidural space during the treatment of labor pain with a combined spinal/epidural (CSE) increases the amount of pain relief obtained and…
- Trial name
- NCT01062893
- Testing
- Sterile normal saline 0 mls, 15 mls sterile normal saline
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Wake Forest University Health Sciences
Pain, Premature Infant
Efficacy of Breast Milk Expressed and Sucrose in Procedural Pain in Preterm
The aim of this study is to assess the non-inferiority of non- pharmacological breast milk expressed versus oral sucrose in relief procedural pain of venipuncture in preterm neonates.
- Conditions
- Pain, Premature Infant, Human Milk, Breastfeeding
- Trial name
- LACTEET (NCT02133716)
- Testing
- expressed breast milk, sucrose 24% oral
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Newborn Care, Pain Management
The Effect of Breast Milk, 10% and 20% Dextrose on Pain and Physiological Variables During Heel Puncture in Infants
Pain, defined by the International Association for the Study of Pain as a subjective, sensory, and emotional experience, differs from nociception, which is merely a neural activity.
- Conditions
- Newborn Care, Pain Management, Physiological Parameters During Newborn Care İn Newborn's, Breast Milk
- Trial name
- NCT07716813
- Testing
- Administering oral breast milk in a supportive position, Administering oral 10% dextrose in a supportive position, Administering oral 20% dextrose in a supportive position
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Mersin University
Preterm, Pain, Acute
Comparison Three Methods on Endotracheal Aspiration in Preterm Infants
Stress and pain control are vital for newborns, especially preterm babies. While painful procedures cause physiological changes in the short term, they negatively affect brain development in the long term.
- Conditions
- Preterm, Pain, Acute, Physiological Stress, Nursing Care
- Trial name
- NCT05434364
- Testing
- Facilitated Tucking, Swaddling, Prone Position
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Postoperative, Premature Infant
Postoperative Pain Control & Relief in Neonates
Pain control for newborns has made significant improvements over the last 30 years. The use of narcotics remains the standard of care for neonates undergoing minor and major surgeries.
- Conditions
- Pain, Postoperative, Premature Infant, Opioid Use
- Trial name
- POPCORN (NCT03677830)
- Testing
- Acetaminophen, Saline
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Lower Back Pain, Pelvic Pain
Musculoskeletal and Obstetric Management Study
The investigators propose such a trial to compare a Musculoskeletal and Obstetric Management (MOM) program to standard obstetric care alone for lower back pain/pelvic pain (LBP/PP) during and after pregnancy.
- Conditions
- Lower Back Pain, Pelvic Pain, Musculoskeletal Pain
- Trial name
- MOMS (NCT00905112)
- Testing
- Manual Therapy, Standard OB Care
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- Logan College of Chiropractic
Preterm, Pain
Reducing Pain During Orogastric Tube Placement in Preterm
The aim of this study is to determine the effectiveness of 3 different methods (breast milk pacifier, sucrose pacifier and pacifier) in reducing pain caused by Orogastric Tube (OGT) insertion in preterm newborns by monitoring…
- Conditions
- Preterm, Pain, Nursing Caries
- Trial name
- NCT05430100
- Testing
- The effect of usıng breast mılk pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns, The effect of usıng sucrose pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns, The effect of usıng pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Pain, Newborn
The Effects of Different Procedures on Pain Levels at Preterm and Term Infants in Neonatal Intensive Care Unit
Accurate assessment of pain in neonates in the neonatal intensive care unit (NICU) is vital because of the high prevalence of painful experiences, including both daily procedural pain and postoperative pain, in this population.
- Conditions
- Pain, Newborn, Preterm, Term
- Trial name
- PAIN (NCT05077345)
- Where
- Turkey (Türkiye)
- Volunteers
- 196 people
- Sponsor
- Sanko University
Preterm Birth, Pain, Acute
Reducing Pain During Heel Blood Collection in Preterm Newborns
Pharmacological and non-pharmacological methods are used to control interventional pain in preterm newborns. Non-pharmacological methods should be preferred in the management of pain, especially during painful minor invasive…
- Trial name
- NCT05431452
- Testing
- Pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Pain
Aromatherapy for Reducing Labor Pain
Pregnant women who eligible with inclusion criteria are random to two groups. Aromatherapy group will receive the aromatherapy during labor along with standard pain control.
- Trial name
- NCT03098212
- Testing
- Aromatherapy
- Volunteers
- 94 people
- Sponsor
- Chiang Mai University
PreTerm Neonate
Effect of Nursing Interventions on Pain and Salivary Cortisol Levels During Heel Stick in Preterm Newborns
Babies born before the thirty-seventh gestational week are called preterm or premature. Most preterm newborns require Neonatal Intensive Care Unit (NICU) care depending on their gestational age and clinical condition.
- Trial name
- NCT06628232
- Testing
- pacifier with breast milk, heel heating, interventions combined
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Premature, Neonatal Intensive Care Unit
The Effect of Gentle Human Touch and Stimulus Reduction on Pain and Comfort During Heel Blood Collection in Premature Newborns
Premature infants frequently experience painful procedures during their admission to neonatal intensive care units; this can lead to acute adverse events, imbalances, and long-term neurodevelopmental implications.
- Conditions
- Premature, Neonatal Intensive Care Unit, Touch, Nursing Care
- Trial name
- NCT07715682
- Testing
- Gentle Human Touch, Environmental Modification
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kubra Nur Kabakcı Sarıdağ
Pain, Fever
Pharmacokinetics, -Dynamics and Safety of Intravenous Paracetamol in Neonates
The purpose of this study is triple, i.e. document single dose pharmacokinetics and -dynamics of intravenous paracetamol in preterm and term neonates after a loading dose (20 mg/kg iv bolus paracetamol), document multiple dose…
- Trial name
- PARANEO (NCT00969176)
- Testing
- paracetamol
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Neonatal Pain, Retinopathy of Prematurity (ROP)
Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants
The goal of this clinical trial is to learn whether intranasal fentanyl (a pain medicine given as a nasal spray) can reduce pain and is safe to use during routine eye examinations for retinopathy of prematurity (ROP) in preterm…
- Conditions
- Neonatal Pain, Retinopathy of Prematurity (ROP), Pain Management, Infant, Premature
- Trial name
- FIREFLY (NCT07112430)
- Testing
- Fentanyl Citrate (Intranasal)
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- Marsha Campbell-Yeo
Pregnancy, Breech Presentation
Effects of Relaxing Hydrotherapy in Third Trimester of Pregnancy
This study will be the first scientific approach to investigate physical and psychological effects of the passive hydrotherapy-method WATSU (WaterShiatsu) on women and their unborn children at the third trimester of pregnancy.
- Conditions
- Pregnancy, Breech Presentation, Low Back Pain, Stress, Psychological
- Trial name
- NCT01708018
- Testing
- WATSU
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Labor Pain
Pain Relief Effects on Length of Labor
This study divides patients into two groups when they ask for medicine to help relieve the pain of contractions. One group will be selected to receive an epidural and another group will be selected to receive both a spinal dose…
- Trial name
- NCT01750099
- Testing
- Combined Spinal-epidural, Continuous Lumbar epidural
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- University of Texas Southwestern Medical Center
Premature, Pneumonia
Respiratory Physiotherapy Change Premature Pain With Pneumonia
Objective to evaluate the effects of vibration techniques and acceleration of expiratory flow on pain parameters in preterm infants diagnosed with pneumonia hospitalized in the Intensive Care Unit and Neonatal Intermediate Care…
- Conditions
- Premature, Pneumonia, Pain, Physiotherapy
- Trial name
- RPCPPWP (NCT03027206)
- Testing
- Vibration technique, Acceleration of expiratory flow
- Volunteers
- 28 people
- Sponsor
- Amazon University
Pain, Postoperative, Gynecologic Surgical Procedures
Comparison of Subcuticular Suture Versus Surgical Staples for Closure of Pfannenstiel Skin Incisions
This study compares methods of closure for Pfannenstiel incisions commonly used during gynecological and obstetrical surgery. Patients are assigned to closure by either surgical staples or a buried suture.
- Conditions
- Pain, Postoperative, Gynecologic Surgical Procedures, Obstetric Surgical Procedures
- Trial name
- NCT00186732
- Testing
- Subcuticular Suture, Surgical Staples
- Where
- Canada
- Volunteers
- 288 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Prematurity, Mechanical Ventilation
Effects of Therapeutic Positioning in Mechanically Ventilated Preterm Infants
This randomized controlled trial evaluated the effects of three therapeutic positions on physiological parameters, pain, and comfort in mechanically ventilated preterm infants.
- Trial name
- NCT07845435
- Testing
- Supine Position, Prone Position, Fetal Position
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mustafa Kemal University
Labor Pain
Effect of Music in Labor in Women Who Underwent Induction of Labor
Women's experience of pain during labor varies greatly, and pain control is a major concern for obstetricians. Several methods have been studied for pain management for women in labor, including drug and non-drug interventions…
- Trial name
- NCT04662424
- Testing
- music in labor
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Federico II University