Clinical trials: Obstructive Sleep Apnea Hypopnea
Apnea, Obstructive Sleep
Associations Apnoea Hypopnoea Index (AHI) and Malocclusions in Growing Patients With Maxillary Constriction
The aim of this prospective clinical study is to evaluate the association between the Apnoea Hypopnoea Index (AHI) and the type of malocclusion in pediatric patients with maxillary constriction.
- Trial name
- NCT07009535
- Testing
- Polysomnography
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Pavia
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Malocclusion
Multi-disciplinary Diagnosis and Treatment Process and Evaluation System for Children With Sleep Disordered Breathing and Malocclusion
The aim of this study is to compare the efficacy and safety of drug therapy, tonsillar adenoidectomy only, orthodontic treatment only and tonsillar adenoidectomy plus orthodontic treatment in children with obstructive sleep apnea…
- Trial name
- NCT03451318
- Testing
- Mometasone Furoate Nasal Spray, tonsillar adenoidectomy, Maxillary expander plus Twin-Block
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Stomotological Hospital
Obstructive Sleep Apnea Hypopnea Syndrome
Contribution of Drug Induced Sleep Endoscopy of Pediatric Obstructive Sleep Apnea Hypopnea Syndrome
The role of drug-induced sleep endoscopy (DISE) in the management of obstructive sleep apnea hypopnea syndrome (OSAHS) is not precisely defined for children.
- Trial name
- ESSI (NCT03845062)
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Montpellier
Obstructive Sleep Apnea
Coblation-Tonsillotomy vs Electrocautery-Tonsillectomy for the Treatment of Obstructive Sleep Apnea (OSA) in Children
Removal of the adenoid and tonsils, known as an adenotonsillectomy (AT) is one of the most frequently performed surgical procedures in North America.
- Trial name
- NCT00694772
- Testing
- Electrocautery-tonsillectomy, Coblation-tonsillotomy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Obstructive Sleep Apnoea
The Use of Oral Appliances as an Adjunct to Continuous Positive Airway Pressure (CPAP) in the Treatment of Obstructive Sleep Apnoea
This study will look at whether patients with OSAHS already successfully treated with nasal CPAP could successfully use an oral appliance as a short-term treatment alternative and whether patients who could use an oral appliance…
- Trial name
- NCT00358605
- Testing
- The Klearway™ oral appliance
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of British Columbia
Sleep Apnea, Obstructive
Establishment of a Diagnosis and Treatment System for Information Processing Damage in Children With OSAHS
Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common childhood sleep disorder with an incidence of 3% . Studies have confirmed that OSAHS can cause multiple systemic dysfunction in children, especially affecting…
- Trial name
- NCT04080089
- Testing
- Surgical treatment, drug therapy, remote cognitive training
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Obstructive Sleep Apnea Syndrome
Follow-up Studies of Primary Snoring(PS) and Obstructive Sleep Apnea Hypopnea Syndrome(OSAHS) in Chinese Children
The study is designed to investigate the natural course of Primary snoring in 1-2 years or more and the different effect of drug and surgical treatment applied in children with obstructive sleep apnea (OSAS) by comparing the…
- Trial name
- NCT02447614
- Testing
- Adenotonsillectomy, Conservative treatment, no treatment
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Children's Hospital
Narcolepsy, Sleep Apnea, Obstructive
PROVIGIL® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome
The primary objective of the study is to evaluate the safety and tolerability of treatment with PROVIGIL in children and adolescents with excessive sleepiness (ES) associated with narcolepsy or OSAHS (obstructive sleep…
- Trial name
- NCT00107848
- Testing
- Modafinil
- Where
- 61 sites in United States, Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Cephalon
Sleep Apnea, Obstructive
Pediatric Obstructive Sleep Apnea Diagnosis by Respiratory Polygraphy
Respiratory polygraphy (RP) can be used to detect obstructive sleep apnea syndrome in children (OSA) , but it underestimates the obstructive apnea-hypopnea index (OAHI) because hypopneas associated with cortical arousals are not…
- Trial name
- NCT06754800
- Testing
- Polysomnography in routine care
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Central Hospital, Nancy, France
Narcolepsy
Assess the Safety and Effectiveness of PROVIGIL Treatment in Children and Adolescents With Excessive Sleepiness
The primary objective of the study is to evaluate the safety and tolerability of treatment with PROVIGIL in children and adolescents with excessive sleepiness (ES) associated with narcolepsy or obstructive sleep apnea/hypopnea…
- Trial name
- NCT00214968
- Testing
- Modafinil
- Volunteers
- 92 people
- Sponsor
- Cephalon
Sleep Apnea, Children
Prevalence of Sleep Apnea/Hypopnea Syndrome in Obese Children
Principal aim: To determine the prevalence of Sleep Apnea- Hypopnea syndrome in obese children. Secondary aim: 1. To fix the implication of the adenotonsillar hypertrophy, the obesity and the hormonal factors in the pathogeny of…
- Conditions
- Sleep Apnea, Children, Obesity
- Trial name
- NANOS (NCT01322763)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Pediatric Sleep Apnea
Clinical Predictors of Pediatric OSAHS
The purpose of this study is to develop adequate and satisfactory tools using reliable clinical and physical factors in predicting pediatric obstructive sleep apnea/hypopnea syndrome (OSAHS) and allow greater access to…
- Trial name
- PEDOSA (NCT02627937)
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Obstructive Sleep Apnea-Hypopnea Syndrome, Anxiety Disorders
EGR2 and NLRP3 Pathways in Obstructive Sleep Apnea-Related Cognitive and Mood Disorders
Obstructive sleep apnea-hypopnea syndrome (OSAS) is a common disorder in which repeated airway blockages during sleep lead to low oxygen levels, inflammation, and disrupted sleep.
- Conditions
- Obstructive Sleep Apnea-Hypopnea Syndrome, Anxiety Disorders, Depressive Disorders
- Trial name
- NCT07120711
- Testing
- EGR2/NLRP3 pathway activity, fatty tissue
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Pediatric Sleep Disordered Breathing, Obstructive Sleep Apnea
Pediatric/Adolescent WatchPAT 400 Reliability Pilot Study
The goal of this clinical trial is to learn whether a newer sleep-testing device gives results that closely match the standard overnight sleep study, in children and adolescents ages 6-18 who are being evaluated for possible…
- Trial name
- NCT07851402
- Testing
- WatchPAT 400
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Milton S. Hershey Medical Center
Obstructive Sleep Apnea Hypopnea Syndrome
Feasibility in Every Day Pratice in an ENT Department and Value of the Automatic Detection of Respiratory Events
The use of respiratory polygraphy (RP) in children for the diagnosis of obstructive sleep apnea hypopnea syndrome (OSAHS) can be challenging: device acceptance, sensors displacement.
- Trial name
- NCT03817762
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Montpellier
Asthma, Bronchial, Bronchial Asthma
Sleep Apnea in Asthmatic Children and Teenagers
Asthma and sleep apnea are both respiratory diseases and one can worsen the other. Those who suffer from asthma have a higher risk of sleep apnea and sleep apnea can make the asthma more difficult to control.
- Conditions
- Asthma, Bronchial, Bronchial Asthma, Apnea, Sleep, Sleep Apnea, Mixed Central and Obstructive
- Trial name
- NCT03034447
- Testing
- Questionnaire, Lung Function Test, Home Sleep Study
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of São Paulo
Obstructive Sleep Apnea, Transverse Maxillary Deficiency
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Transverse Orthodontic Deficiency in Children
OSAHS (Obstructive Sleep Apnea Hypopnea Syndrome) in children is a frequent respiratory disorder, whose prevalence is estimated at between 1.2 and 5.7%, and which, if left untreated, can cause severe medical complications.
- Trial name
- ASCOT (NCT07086612)
- Testing
- over nigtht ventilatory polysomnograph test
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Sleep Apnea, Home Respiratory Polygraphy Sleep Study
Home Respiratory Polygraphy in Childhood Sleep Apnea-Hypopnea Syndrome (CHILDSLEEP).
The aims of the study is to assess the diagnostic utility of home respiratory polygraphy (HRP) complemented with polysomnography (PSG) in childhood Obstructive Sleep Apnea-Hypopnea Syndrome (OSAS), as well as its usefulness in…
- Conditions
- Sleep Apnea, Home Respiratory Polygraphy Sleep Study, Childhood Sleep Apnea, Polysomnography
- Trial name
- CHILDSLEEP (NCT04340310)
- Testing
- Home respiratory polygraphy
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- Hospital Universitario San Juan de Alicante
Infrared-thermal-imaging
Evaluation of Infrared Thermal Imaging in Diagnosis of OSAHS in Children
OSAHS is a common sleep breathing disorder in children, with the same incidence as childhood asthma, and is mainly caused by upper airway stenosis caused by tonsil/adenoid hyperplasia.
- Trial name
- NCT05830227
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- State Key Laboratory of Respiratory Disease
Sleep Apnea, Obstructive
Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome
The primary objectives of the study are to determine the effectiveness of PROVIGIL treatment, compared to placebo treatment, in children and adolescents with excessive sleepiness (ES) associated with obstructive sleep…
- Trial name
- NCT00107809
- Testing
- Modafinil
- Where
- 64 sites in United States, Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cephalon