Clinical trials: Obstructive Ventilation Disorder
Emphysema
Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine if osteopathic manipulative treatment (OMT) is effective for persons with emphysema as a component of their chronic obstructive pulmonary disease.
- Trial name
- NCT00034112
- Testing
- osteopathic manipulative treatment
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Obstructive Sleep Apnea of Child, Sleep-Disordered Breathing
Comparison of Two Reeducation Methods in Children With Persistent Sleep Apnea, a Randomized Controlled Trial
Myofunctional therapy has been shown to be effectively reduce symptoms of paediatric obstructive sleep apnea, usually performed after adenotonsillectomy.
- Conditions
- Obstructive Sleep Apnea of Child, Sleep-Disordered Breathing, Adenotonsillar Hypertrophy
- Trial name
- PERSIST-B-RCT (NCT06634264)
- Testing
- Soft Oral Appliance
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Université de Montréal
Asthma, Bronchial, Bronchial Asthma
Sleep Apnea in Asthmatic Children and Teenagers
Asthma and sleep apnea are both respiratory diseases and one can worsen the other. Those who suffer from asthma have a higher risk of sleep apnea and sleep apnea can make the asthma more difficult to control.
- Conditions
- Asthma, Bronchial, Bronchial Asthma, Apnea, Sleep, Sleep Apnea, Mixed Central and Obstructive
- Trial name
- NCT03034447
- Testing
- Questionnaire, Lung Function Test, Home Sleep Study
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of São Paulo
Bronchiolitis, Respiratory Distress
Hypertonic Saline for Outpatient Bronchiolitis
We will study if small children who become ill with respiratory distress during the RSV epidemic are better relieved with salbutamol nebulizations diluted in hypertonic (3%), instead of normal (0.9%) saline.
- Trial name
- Hypertonic (NCT00696540)
- Testing
- Inhalation of salbutamol diluted in hypertonic saline, Inhalation of salbutamol diluted in normal saline
- Where
- Chile
- Volunteers
- 74 people
- Sponsor
- University Diego Portales
Enuresis, Obstructive Sleep Apnea
Intranasal Steroids for the Treatment of Nocturnal Enuresis With Associated Obstructive Sleep Apnea
Enuresis (E) or bedwetting is a common pediatric complaint, and recent research has discovered a link with obstructive sleep apnea (OSA).
- Conditions
- Enuresis, Obstructive Sleep Apnea, Sleep Disordered Breathing
- Trial name
- NCT01861145
- Testing
- Bed Alarm, Nasonex
- Where
- 2 sites in Canada
- Sponsor
- University of Alberta
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Malocclusion
Multi-disciplinary Diagnosis and Treatment Process and Evaluation System for Children With Sleep Disordered Breathing and Malocclusion
The aim of this study is to compare the efficacy and safety of drug therapy, tonsillar adenoidectomy only, orthodontic treatment only and tonsillar adenoidectomy plus orthodontic treatment in children with obstructive sleep apnea…
- Trial name
- NCT03451318
- Testing
- Mometasone Furoate Nasal Spray, tonsillar adenoidectomy, Maxillary expander plus Twin-Block
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Stomotological Hospital
Sleep Apnea, Obstructive, Sleep Disorder
HSAT for OSA Management in Children
This clinical trial will compare the diagnostic accuracy of type II HSAT with PSG for determining OSA status following treatment with adenotonsillectomy in children
- Conditions
- Sleep Apnea, Obstructive, Sleep Disorder, Sleep Apnea Syndromes, Sleep Disturbance
- Trial name
- HOM-Kids (NCT05516524)
- Testing
- Home sleep apnea test, PSG
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Children's Hospital of Philadelphia
Asthma, Recurrent Cough
Spirometry and Methacholine Challenge Test in Asthmatic Children Age 3-6years
Rational: The possible contribution of methacholine challenge test via spirometry to the clinical diagnosis of young children with various respiratory symptoms, the most appropriate spirometry index, and the proper cutoff point…
- Trial name
- MCH-preschool (NCT00550758)
- Testing
- Methachoine, spirometry
- Volunteers
- 84 people
- Sponsor
- Rambam Health Care Campus
Chronic Obstructive Pulmonary Disease (COPD), Anxiety
Pilot Study on Mindfulness Based Stress Reduction (MBSR) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This two-phase exploratory pilot study investigates the impact of a Mindfulness-Based Stress Reduction (MBSR) program on patients with chronic obstructive pulmonary disease (COPD) undergoing pulmonary rehabilitation.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Anxiety, Depression Disorders, Stress
- Trial name
- NCT07593521
- Testing
- Mindulness Based Stress Reduction program
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- Université Libre de Bruxelles
Obstructive Sleep Apnea
Indoor Temperature and Sleep Apnea
The purpose of this study is to test whether different indoor temperature affect the frequency of sleep apnea.
- Trial name
- NCT00544752
- Testing
- 16, indoor temperature of 20 degrees celcius, indoor temperature of 24 degrees celcius
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Umeå University
Stem Cell Transplant Complications, Respiratory Disease
Efficacy of Fluticasone Propionate Associated With Salmeterol Using Inhalation Chamber Versus Placebo to Improve the Respiratory Function in Children Over Six Years of Age Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation With a Decline of FEV1 ≥10% From Pre Transplantation
Bronchiolitis Obliterative Syndrome (BOS) is the primary noninfectious pulmonary complication after hematopoietic stem cell transplantation (HSCT) and usually carries a poor prognosis.
- Conditions
- Stem Cell Transplant Complications, Respiratory Disease, Bronchiolitis Obliterans
- Trial name
- RESPPEDOBS (NCT04655508)
- Testing
- Seretide
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Obstructive Pulmonary Disease, COPD
The Effect of Breathing Helium-Hyperoxia During Pulmonary Rehabilitation in Patients With COPD
The purpose of this study is to examine whether breathing helium-hyperoxia during exercise in a pulmonary rehabilitation program can improve the exercise tolerance and health related quality of life of patients with Chronic…
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Emphysema, Lung Diseases
- Trial name
- NCT00406705
- Testing
- Helium-Hyperoxia
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Obstructive Sleep Apnea Syndrome, Cleft Lip/Palate
A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/Palate
The study is to examine the relationship between sleep apnea and neurocognitive behaviors in children with cleft lip/palate. Describe the incidence and severity of obstructive sleep apnea in an unselected population of grade…
- Trial name
- NCT00156442
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Obstructive Sleep Apnea
Remifentanil in Children With Obstructive Sleep Apnea
This investigation tested the hypothesis that children with obstructive sleep apnea have an increased pharmacodynamic sensitivity to the miotic and respiratory depressant effects of the prototypic μ-opioid agonist remifentanil.
- Trial name
- ROSA (NCT03958396)
- Testing
- Remifentanil Infusion
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
COPD, Interstitial Lung Disease
Autologous Stem Cell Treatment for Chronic Lung Disease Study
The purpose of the Lung Institute is to collect and isolate a patient's own cells and platelet rich plasma (PRP) and deliver the product back to the patient the same day.
- Trial name
- NCT03044431
- Testing
- Cell therapy
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- Lung Institute
Sleep Apnea, Obstructive
OSA (oRisk of Obstructive Sleep Apnea and Traffic Accidents Among Bus Drivers in Ecuador: is There a Significant Association
Our study aims to determine the frequency of individuals at high risk of obstructive sleep apnea, and excessive daytime sleepiness, as well as any potential association between these conditions and traffic accidents among a…
- Trial name
- NCT05175287
- Where
- Ecuador
- Volunteers
- 340 people
- Sponsor
- Respiralab
Chronic Obstructive Pulmonary Disease
ACBT and High Frequency Chest Wall Oscillations in COPD Patients
Chronic obstructive pulmonary disease (COPD) patients with mucus hyper secretion tend to demonstrate increased frequency of infective exacerbations and a steeper slope of decline in lung function.
- Trial name
- NCT05424133
- Testing
- High frequency chest wall oscillation, Active cycle of breathing
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Pulmonary Disease, Chronic Obstructive
Shortness Of Breath Questionnaire Validation Study
This study will last for approximately 8 weeks and will involve 4 visits. The study is being carried out to validate a shortness of breath questionnaire
- Trial name
- NCT00411372
- Testing
- fluticasone propionate/salmeterol 250/50mcg combination, salmeterol 50mcg
- Sponsor
- GlaxoSmithKline
Obstructive Sleep Apnea
Decrease Emergence Agitation and Provide Pain Relief for Children Undergoing Tonsillectomy & Adenoidectomy
Pediatric tonsillectomy (with or without adenoidectomy) is a brief but painful surgery carried out in children who very often also present with obstructive sleep apnea. To provide pain relief, i.e.
- Trial name
- NCT00468052
- Testing
- dexmedetomidine, fentanyl
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Recurrent Tonsillitis, Obstructive Sleep Apnea
Post-operative Pain Control After Pediatric Adenotonsillectomy
Adenotonsillectomy is one of the most common surgical procedures performed in the pediatric population in the United States. It is generally a well-tolerated procedure with post-operative bleeding risk ranging from 3-5% in…
- Conditions
- Recurrent Tonsillitis, Obstructive Sleep Apnea, Sleep Disordered Breathing, Adverse Reaction to Drug
- Trial name
- NCT02296840
- Testing
- Ibuprofen, Hydrocodone-Acetaminophen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Emory University