Clinical trials: Occlusion of Artery
Uterine Fibroids (Leiomyoma), Myomectomy
Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy
The current study is a multiple-arm, single blinded, and controlled randomized trial. It will be conducted in two gynecological endoscopy centers: • ElShatby University Hospital, a tertiary level hospital in Alexandria, Egypt.
- Conditions
- Uterine Fibroids (Leiomyoma), Myomectomy, Myomectomy; Surgical Blood Loss
- Trial name
- NCT07352761
- Testing
- Temporary clipping of uterine artery, Temporary occlusive suturing of uterine artery, Bipolar coagulation of uterine arteries
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Atherosclerosis
Comparison of Magnetic Resonance Angiography and Standard Angiography in Diagnosing Atherosclerosis
This study will evaluate ways to improve magnetic resonance angiography (MRA) for diagnosing atherosclerosis (hardening and narrowing of the arteries).
- Trial name
- NCT00001946
- Testing
- Magnetic resonance angiography
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Coronary Artery Disease
Different Regimen of Aprotinine(Trasylol) Administration in Patients Receiving Antiplatelet Therapy With Clopidogrel (Plavix)
Clopidogrel (Plavix), a platelet ADP receptor antagonist, has become the standard of care to prevent thrombosis in interventional cardiology and is increasingly being used in unstable angina and NSTEMI.
- Trial name
- NCT00257751
- Testing
- Aprotinine
- Volunteers
- 400 people
- Sponsor
- Oslo University Hospital
Chronic Total Occlusion of Coronary Artery
CrossBoss and Hybrid Registry on Coronary Chronic Total Occlusions
The successful re-opening of a blocked coronary artery has a beneficial effect on the further clinical course (e.g. improvement of clinical symptoms, improved quality of life, increased heart function, etc.).
- Trial name
- RECHARGE (NCT02075372)
- Testing
- Data registration
- Where
- 21 sites in Belgium, France and 2 more
- Volunteers
- 1,177 people
- Sponsor
- Hasselt University
Peripheral Arterial Disease (PAD)
Zilver Flex Post-Market Study in Japan
Japanese post market clinical study of the Zilver Flex device.
- Trial name
- NCT02254356
- Testing
- Zilver Flex Bare Metal Stent
- Where
- Japan
- Volunteers
- 239 people
- Sponsor
- Cook Group Incorporated
Coronary Artery Disease
Ezetimibe Versus Nutraceuticals in Statin-intolerant Patients
Pharmacologic alternatives in statin-intolerant patients include ezetimibe and nutraceuticals (i.e. compounds derived from foods with cholesterol lowering actions).
- Trial name
- ECLIPSE (NCT01490229)
- Testing
- Ezetimibe, Nutraceuticals
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Moyamoya Disease
Functional Disorders Moya Moya Young Patients
Moya Moya disease is a rare condition of the vessels that supply blood to the brain. It normally occurs without apparent cause. In both children and adults, the disease is mainly manifested by strokes.
- Trial name
- TFMoya : ADAR (NCT05772572)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Carotid Artery Plaque
TMAO and Atherosclerosis in HIV
In the present study, the investigators sought to prospectively examine the associations of plasma levels of TMAO (trimethylamine oxide), choline, betaine, dimethylglycine, and sarcosine with risk of incident carotid artery…
- Trial name
- NCT03416257
- Testing
- No intervention
- Volunteers
- 737 people
- Sponsor
- Albert Einstein College of Medicine
Aortic Valve Disease, Coronary Artery Disease
Early Outcomes of Concomitant Transcatheter Aortic Valve Implantation and Off-pump Coronary Artery Bypass Grafting in Management of Severe Symptomatic Aortic Stenosis and Coronary Artery Disease
Study Objectives/Specific Aims Overall Goal: To study the outcomes of patients undergoing TAVI, their subsequent results and complications.
- Trial name
- NCT04525339
- Testing
- TAVI and Off pump CABG
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Atherosclerosis, Heart Failure, Congestive
The Role of Angiotensin Type I Receptor in the Regulation of Human Coronary Vascular Function
The renin angiotensin system (RAS) plays an important physiological and pathophysiological role in the control of blood pressure and plasma volume.
- Conditions
- Atherosclerosis, Heart Failure, Congestive, Hypertension, Myocardial Infarction
- Trial name
- NCT00001629
- Testing
- Angiotensin II type 1 receptor antagonists
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-2 Study
The purpose of this study is to evaluate the safety of reducing dual antiplatelet therapy (DAPT) duration to 1 month after implantation of the everolimus-eluting cobalt-chromium stent (CoCr-EES).
- Trial name
- STOPDAPT-2 (NCT02619760)
- Testing
- 1-month DAPT, 12-month DAPT
- Where
- Japan
- Volunteers
- 3,045 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Critical Limb Ischemia, Arterial Occlusive Disease
Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia
The hypothesis behind the trial is the concept that Pregabalin is effective in reducing pain at rest in lower limb ischemia, and the study evaluates active treatment or placebo added to the regular pain regimens for these…
- Conditions
- Critical Limb Ischemia, Arterial Occlusive Disease, Pain, Ischemia
- Trial name
- NCT00403780
- Testing
- pregabalin
- Where
- 3 sites in Sweden
- Volunteers
- 18 people
- Sponsor
- Karolinska Institutet
Atherosclerosis
Study to Investigate the Sensitivity and Specificity of 3.0 Tesla MRI for Carotid Artery Plaque
The aim of this study is to develop non-invasive MRI, and MRS approaches that will quantify the plaque composition and lipid content of plaques and will have the potential for repeated in vivo measurements.
- Trial name
- NCT01632254
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Coronary Artery Disease (CAD), Chronic Total Occlusion of Coronary Artery
Predictors and Long-term Incidence of In-stent Restenosis After Chronic Total Occlusion Percutaneous Coronary Intervention
The goal of this clinical trial is to describe the long-term (≥ 3 years) patency of coronary artery stents following chronic total occlusion percutaneous coronary intervention (CTO PCI).
- Conditions
- Coronary Artery Disease (CAD), Chronic Total Occlusion of Coronary Artery, Chronic Total Occlusion (CTO)
- Trial name
- NCT07473596
- Testing
- chronic total occlusion percutaneous coronary intervention (CTO PCI), coronary computed tomography angiography, invasive coronary angiography
- Where
- Finland
- Volunteers
- 294 people
- Sponsor
- Lauri Mansikkaniemi
Coronary Artery Disease
OCT and Scaffold Embedding After NC Balloon
This study is a single-center, prospective, observational study designed to subjects presenting with stable angina pectoris or acute coronary syndromes requiring treatment of de novo lesions.
- Trial name
- NCT03106961
- Testing
- Bioresorbable vascular scaffolds, OCT, non-compliant ballooning
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- St. Francis Hospital, New York
Aortic Valve Stenosis
Non-Contrast Magnetic Resonance Angiography Assessment of Patients Referred for Transcatheter Aortic Valve Implantation
The overall objective of this proposal is to examine the feasibility and accuracy of non-contrast magnetic resonance angiography (MRA) to comprehensively evaluate individuals referred for transcatheter aortic valve implantation…
- Trial name
- NCT02007967
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Moya Moya Disease
Moya Moya Syndrome With or Withtout Sickle Cell Disease
Moya Moya disease or syndrome ar characterized by a progressive or occlusion of the intracranial carotid arteries and their mainproximal branches, followed by the development of fragile neovessels at the base of the skull, leding…
- Trial name
- BMM-ScD (NCT05050344)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Peripheral Arterial Disease
Randomized Clinical Trial for Ewing Amputation in the VA
This study follows the Pilot Investigation of Ewing Amputation for Veterans with PAD Undergoing a Below Knee Amputation. The 2 year pilot feasibility phase has concluded recruitment and enrollment.
- Trial name
- NCT05437562
- Testing
- Ewing Below Knee Amputation, Standard Below Knee Amputation
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Renal Artery Obstruction, Hypertension, Renovascular
A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension
A prospective Danish national registry of percutaneous transluminal renal angioplasty (PTRA) in high-risk patients with renal artery stenosis selected on the basis of common national criteria, and with a common follow-up protocol…
- Conditions
- Renal Artery Obstruction, Hypertension, Renovascular, Cardiovascular Diseases, Kidney Diseases
- Trial name
- DAN-PTRA (NCT02770066)
- Testing
- Percutaneous transluminal renal angioplasty
- Where
- 5 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- University of Aarhus
Carotid Stenosis, Carotid Endarterectomy
Major Adverse Cardiac Events After Carotid Endarterectomy
Carotid endarterectomy is the operation for curing the significant carotid artery stenotic patients who are also at high cardiac risk. This retrospective study is to find out the incidence and risk factors related.
- Conditions
- Carotid Stenosis, Carotid Endarterectomy, Adverse Cardiac Events
- Trial name
- NCT03596229
- Where
- Thailand
- Volunteers
- 175 people
- Sponsor
- Mahidol University