Clinical trials: Ocular Surface
Ocular Surface Allergy, Conjunctivitis, Allergic
Treatment of Ocular Surface Inflammations
The goal of this clinical trial is to learn if topical Cyclosporine 1% works to treat severe allergic ocular surface inflammation in pediatric population.
- Conditions
- Ocular Surface Allergy, Conjunctivitis, Allergic, Blepharoconjunctivitis
- Trial name
- NCT07732855
- Testing
- Topical Cyclosporine 1%
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Ocular Surface Disease, Premature
Impact of Prematurity on the Optic Nerve
The purpose of this protocol is to study the consequences of prematurity on the optic nerve. Indeed, the work already carried out on the subject suggests that prematurity induces suffering of the optic nerve with a loss of…
- Trial name
- NCT04067973
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Nantes University Hospital
Ocular Surface Disease, Inflammatory Disease
Establishment of a Multimodal Standard Database for Inflammation-related Ophthalmopathy
Through a systematic observational study, the intrinsic connections and patterns between the occurrence and development of common blinding retinal diseases such as diabetic retinopathy, pathological myopia, and age-related…
- Conditions
- Ocular Surface Disease, Inflammatory Disease, Retinal Disease, Choroid Diseases
- Trial name
- NCT07628946
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Dan Chen
Glaucoma, Ocular Surface Disease
Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications
To evaluate glaucoma patients' response to treatment with Xiidra, an FDA-approved drug for ocular surface discomfort, which will be prescribed as standard of care treatment.
- Trial name
- NCT04354545
- Testing
- Xiidra (Lifitegrast ophthalmic solution) 5%
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Ocular Surface Disease
The Effect of Eye Care With Artificial Tears and Normal Saline on Ocular Surface Disease in Mechanically Ventilated Pediatric Patients
The primary aim of this study is to comparatively examine the effects of eye care practices using artificial tears and normal saline on superficial ocular injuries in pediatric patients receiving mechanical ventilation in the…
- Trial name
- NCT07000565
- Testing
- Eye Care with Artificial Tears, Eye Care with Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Marmara University
Probiotic, Ocular Surface Disease
Efficacy and Safety of Oral Probiotics on Ocular Symptoms and Gut Microbiome of Children with Vernal Keratoconjunctivitis
The primary goal of this study is to determine the effects of oral probiotics on the severity of ocular symptoms and the alterations of the gut microbiome of children (4-18 years old) with vernal keratoconjunctivitis.
- Conditions
- Probiotic, Ocular Surface Disease, Ocular Diseases, Ocular Dryness
- Trial name
- NCT06793514
- Testing
- Probiotic
- Volunteers
- 32 people
- Sponsor
- Mohsen Pourazizi
Ocular Surface Disease
Comparison Between Lathe Cut Versus Cast Molding Soft Contact Lens Technique on Ocular Surface Integrity
"Comparison between Lathe Cut versus Cast Molding Soft Contact Lens Technique on Ocular Surface Integrity" investigates the impact of two different manufacturing methods on the health and integrity of the ocular surface.
- Trial name
- NCT06495112
- Testing
- Soft contact lens with lathe cut technique Lathe, Soft contact lens with cast molding technique
- Where
- Pakistan
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Superior University
COVID-19, Ocular Surface Disease
A Cross-sectional Study of Ocular Manifestations During the Covid-19 Pandemic in Hubei Province
To investigate the clinical features of ocular manifestations during the novel coronavirus pneumonia pandemic in Hubei at the end of 2022
- Trial name
- NCT06355128
- Testing
- NOT
- Where
- China
- Volunteers
- 16,000 people
- Sponsor
- Zhongnan Hospital
Ocular Surface Disease, Irregular Astigmatism
Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia
To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of…
- Conditions
- Ocular Surface Disease, Irregular Astigmatism, Contact Lens Complication, Corneal Astigmatism
- Trial name
- NCT06256770
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Eye Diseases, Ocular Surface Disease
Pediatric Eye Care Investigated Team
Use cohort research to analyze and compare eyes of healthy children and children with systemic diseases. Understand and analyze the incidence, characteristics and influencing factors of children's ocular surface diseases.
- Conditions
- Eye Diseases, Ocular Surface Disease, Systemic Disease, Children
- Trial name
- PECT (NCT05247099)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Eye Diseases, Ocular Surface Disease
Effect on Ocular Surface Symptoms of Online Education
retrospective, observational study.
- Conditions
- Eye Diseases, Ocular Surface Disease, Dry Eye
- Trial name
- NCT04960696
- Testing
- OSDI, tear break up time, schirmer
- Where
- Turkey (Türkiye)
- Volunteers
- 315 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Symblepharon, Dry Eye
Salivary Gland Transplantation in the Treatment of Dry Eye in Patients With Stevens-Johnson Syndrome.
The purpose of this study is to evaluate salivary gland and labial mucous membrane transplantation in patients with severe symblepharon and dry eye secondary to Stevens-Johnson Syndrome (SJS).
- Conditions
- Symblepharon, Dry Eye, Ocular Surface Disease, Transplantation
- Trial name
- NCT01178242
- Testing
- Salivary Gland and Labial Mucous Membrane Transplantation
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Federal University of São Paulo
Ocular Surface Disease
Transplantation of Cultivated Limbal Epithelium on Amniotic Membrane for Limbal Stem Cell Deficiency
To evaluate the effectiveness of autologous (tissue from fellow eye) transplantation of cultivated limbal epithelium on amniotic membrane to treat severe surface irregularity and scarring of the corneal surface.
- Trial name
- NCT00348114
- Testing
- Transplantation of cultivated limbal epithelium
- Volunteers
- 8 people
- Sponsor
- Singapore National Eye Centre