Clinical trials: One-lung Ventilation
Hyperoxemia
A Titration of Fractional Inspired Oxygen Using Oxygen Reserve Index in Child
The purpose of this prospective randomized controlled trial is to determine whether using the Oxygen Reserve Index can prevent hyperoxemia in pediatric patients receiving single-lung ventilation.
- Trial name
- NCT05912543
- Testing
- Titration of FiO2
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital
Surgery, Thoracic
Effect of One-lung Ventilation on BIS Values
In this observational study, all enrolled patients having a thoracic surgical procedure requiring lung isolation will have a bispectral index (BIS) monitor placed at time of induction.
- Trial name
- NCT03962036
- Testing
- Bispectral index monitor
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Christopher McKee
Anesthesia
3D OLV Training Intervention for Pediatric Anesthesia Trainees
One lung ventilation (OLV) in neonates and children is an advanced skill that is necessary for delivery of safe and quality anesthetic care.
- Trial name
- NCT03929315
- Testing
- OLV technique on tracheo-bronchial model
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Clyde Matava
COPD Received PR
Correlation Between Pulmonary Rehabilitation and TFC
To study the effects of lung rehabilitation on the heart's hemodynamic performance of patients with chronic bidirectional lung disease when performing routine and regular PR, and found that the effects of lung rehabilitation on…
- Trial name
- NCT05240989
- Testing
- pulmonary rehabilitation
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Fu Jen Catholic University
Acute Respiratory Distress Syndrome, Severe Pneumonia
One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19
The latest epidemiological data published from Chine reports that up to 30% of hospital-admitted patients required admission to intensive care units (ICU).
- Conditions
- Acute Respiratory Distress Syndrome, Severe Pneumonia, Respiratory Failure
- Trial name
- NCT04457505
- Where
- 31 sites in Spain
- Volunteers
- 8,500 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Bronchiolitis
Automation Oxygen Flow Titration in Spontaneously Breathing Infants
The objective of this study is to assess the efficacy of the FreeO2 device in shortening the hospital length of stay during a first episode of hypoxemic bronchiolitis in infants less than 1 year of age.
- Trial name
- FreeO2Bronchio (NCT03614507)
- Testing
- FreeO2 (modèle FO2-220-00) automatic oxygen flow titration, FreeO2 (modèle FO2-220-00) manual oxygen flow titration
- Where
- 10 sites in France
- Volunteers
- 105 people
- Sponsor
- University Hospital, Brest
One-Lung Ventilation, Thoracic Surgery
Dexmedetomidine Improved Oxygenation and Reduced Shunt in One-Lung Ventilation at High-Risk Pediatric Thoracic Surgery
Children with high anesthetic risk who underwent Thoracic surgery with OLV (one lung ventilation) technique during general anesthesia were divided into two groups.
- Trial name
- NCT06505772
- Testing
- Dexmedetomidine, Normal saline
- Where
- Syria
- Volunteers
- 78 people
- Sponsor
- Damascus University
Mask Ventilation, Obese Patients (BMI ≥ 30 kg/m²)
Comparison of Mask Ventilation in Obese Patients by Differents One Hand Techniques
The goal of this controled clinical trial study to know if hook tecnique method is better than other traditional one hand ventilation methods in acheiving effective ventilation in obese patients .
- Conditions
- Mask Ventilation, Obese Patients (BMI ≥ 30 kg/m²), Obesity & Overweight, Bag-mask Ventilation
- Trial name
- E&c / T&E (NCT06817083)
- Testing
- E-C Clamp Technique, T-E Technique, The Hook Technique
- Where
- Egypt
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Aswan University
Pneumothorax
Disconnection Technique With a Bronchial Blocker for Improving Lung Deflation
One lung ventilation (OLV) is accomplished with a double lumen tube (DLT) or a bronchial blocker (BB). In this study, the investigators compared the effectiveness of lung collapse using DLT, BB with spontaneous collapse, and BB…
- Trial name
- NCT01846936
- Testing
- DLT with conventional technique, BB with conventional technique, Disconnection technique
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Ajou University School of Medicine
Thoracic Surgery
A Clinical Comparison of Three Bronchial Blockers for One-Lung Ventilation in Thoracic Surgery
This is a clinical trial comparing surgical conditions during one-lung ventilation with three different bronchial blockers or with double-lumen endobronchial tubes.
- Trial name
- NCT00188916
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Mechanical Ventilation
Continuous Monitoring of the Lungs Ventilation Dynamics During Mechanical Ventilation
Background: Patients that suffer from respiratory failure and need mechanical ventilation are at risk of further deterioration due to complications induced by progression of lung disease or the mechanical ventilation.
- Trial name
- NCT00702169
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Carmel Medical Center
Neonatal Respiratory Distress Syndrome
Early Neonatal Respiratory Distress: Changes in Level IIb Hospital Over a Period of One Year
Respiratory distress is one of the first hospital grounds during the neonatal period. The clinical presentation and severity vary by gestational age and cause.
- Trial name
- DROPE (NCT02824497)
- Testing
- No intervention. It's a description study
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Thoracic Diseases
Ultrasound to Verify Lung-isolation During Single-lung Ventilation
The purpose of the current study is to prospectively evaluate the usefulness of thoracic ultrasonography in demonstrating effective lung isolation during single-lung ventilation (SLV) in the pediatric patient.
- Trial name
- NCT03729999
- Testing
- Portable, Point-of-Care Ultrasound
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nationwide Children's Hospital
One Lung Ventilation OLV, Esophageal Atresia
The Effect of Dexmedetomidine on Oxygen During One Lung Ventilation in Pediatric Surgery.
The children who will undergo OLV (one lung ventilation) through general anesthesia will be divided into two groups: The first will be intravenous infusion of dexmedetomidine at 0.4 mcg / kg / hour, and the second will be…
- Conditions
- One Lung Ventilation OLV, Esophageal Atresia, Hydrocystoma, Pneumonectomy
- Trial name
- RCT (NCT04932746)
- Testing
- Dexmedetomidine
- Where
- Syria
- Volunteers
- 110 people
- Sponsor
- Damascus University
Pulmonary Disease, Chronic Obstructive
Breathing Helium-Hyperoxia During Exercise in Patients With Chronic Obstructive Pulmonary Disease
Regular exercise can help patients with the lung disease, chronic obstructive pulmonary disease (COPD). But COPD patients have a hard time with training because of their breathing.
- Trial name
- NCT01283685
- Testing
- breathing helium-hyperoxia, breathing supplemental oxygen
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- West Park Healthcare Centre
Double-Lumen Endotracheal Tube Placement
Effect of Head Turn on Double-Lumen Tube Alignment
This study evaluated how simple external airway maneuvers affect the alignment of the left main bronchus during placement of a left-sided double-lumen endotracheal tube.
- Trial name
- NCT07755722
- Testing
- Right Tracheal Displacement, Right Head Turn Maneuver, Left Head Turn Maneuver
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Non Invasive Ventilation Failure in Preterms
Non-invasive Ventilation
Risk factors for non invasive ventilation failure in preterms that lead them to use invasive ventilation
- Trial name
- CPAP (NCT07186790)
- Volunteers
- 160 people
- Sponsor
- Assiut University
One-lung Ventilation (OLV)
Intracuff Pressure During One-lung Ventilation in Infants and Children
The purpose of this study is to evaluate the initial pressure and changes of the intracuff pressure during one-lung ventilation (OLV) in infants and children during thoracic surgery.
- Trial name
- NCT02424487
- Testing
- Intracuff pressure measurement in one-lung ventilation during thoracic surgery
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Joseph D. Tobias
Neonatal Intensive Care
Neonatal Mask Seal; a Two-handed Versus One-handed Approach: The NeoSeal Study
When babies can't breathe effectively, we can use a facemask to give them breaths and oxygen. The mask can be held with one or two hands, depending on the preference of the doctor.
- Trial name
- NeoSeal (NCT06740344)
- Testing
- Two-handed facemask hold, Control: One-handed facemask hold
- Where
- Ireland
- Volunteers
- 110 people
- Sponsor
- University College Dublin
Anesthesia, Surgery
The Effects of Individualized Lung-protective Ventilation With Lung Dynamic Compliance-guided Positive End-expiratory Pressure(PEEP) Titration on Postoperative Pulmonary Complications of Pediatric Video-assisted Thoracoscopic Surgery
This study evaluates the influence of individualized lung-protective ventilation strategy(LPVS) on postoperative pulmonary complications(PPCs) through a randomized controlled trial when children undergoing thoracoscopic surgery…
- Trial name
- PEEP (NCT05386901)
- Testing
- Conventional positive end-expiratory pressure(PEEP), Lung dynamic compliance guided positive end-expiratory pressure(PEEP)
- Where
- China
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Jiaxiang Chen