Clinical trials: Open Abdomen
Wound Infection, Complication
Abdomen CT and Open Appendicectomy：New Diagnostic and Surgical Procedures
The traditional open appendectomy in the clinical effect is not prefect, and for a long time there is no measurable improvement.
- Conditions
- Wound Infection, Complication, Scar
- Trial name
- ACAOA (NCT02574364)
- Testing
- The application of abdomen CT, traditional incision
- Volunteers
- 730 people
- Sponsor
- Ningbo Municipal No.4 Hospital
Abdominal Aortic Aneurysm
Preferences for Open Vs. Endovascular Repair for Abdominal Aortic Aneurysm
This study tests the use of a decision aid for Veterans who are facing a decision about surgery for their Abdominal Aortic Aneurysm (AAA).
- Trial name
- PROVE-AAA (NCT03115346)
- Testing
- Decision aid
- Where
- 22 sites in United States
- Volunteers
- 241 people
- Sponsor
- VA Office of Research and Development
Inguinal Hernia
The (Cost-) Effectiveness of Paediatric Laparoscopic Hernia Repair Compared to Open Hernia Repair
This study assess the (cost-)effectiveness of open versus laparoscopic Percutaneous Inguinal Ring Suturing (PIRS) technique for unilateral inguinal hernia repair in children aged 0-16 years.
- Trial name
- HERNIIA-2 (NCT06451432)
- Testing
- Percutaneous Inguinal Ring Suturing (PIRS) technique
- Where
- 9 sites in Netherlands
- Volunteers
- 464 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Abdominal Wall Hernia
Outcomes of Open Versus Robotic-assisted Laparoscopic Posterior Component Separation in Complex Abdominal Wall Repair
This is a retrospective European multicenter study evaluating surgical treatment of patients with a complex ventral incisional hernia using robotic-assisted laparoscopic transversus abdominis release (rTAR) or open transversus…
- Trial name
- EUROTAR (NCT05195957)
- Testing
- Robotic tranversus abdominis release operation, Open transversus abdominis release operation
- Where
- 2 sites in Belgium, Finland
- Volunteers
- 169 people
- Sponsor
- University of Oulu
Acute Appendicitis, Superficial SSI
Laparoscopic vs Open Appendectomy
his randomized controlled trial was conducted to compare the frequency of superficial surgical site infections (SSIs) following laparoscopic appendectomy and open appendectomy in patients undergoing surgical treatment for acute…
- Trial name
- NCT07841444
- Testing
- Laparoscopic appendectomy, Open Appendectomy
- Where
- Pakistan
- Volunteers
- 276 people
- Sponsor
- Quaid-e-Azam Medical College
Appendicitis Acute
Laparoscopic Versus Open Appendectomy Prospective Randomized Control Study
laparoscopic versus open appendectomy prospective randomized control study.Both surgical methods are safe and well established in clinical practice but there has been a controversy about which surgical procedure is the most…
- Trial name
- NCT05611489
- Testing
- Open appendectomy, Conventional Lap appendectomy
- Volunteers
- 70 people
- Sponsor
- Abanoub Atif Fawzy
Appendicitis
Appendicectomy Skin Closure Technique: Changing Paradigms (ASC)
To compare the results associated with two different skin closure techniques in open appendectomy. 200 patients were included after acute appendicitis diagnosis in emergency department.
- Trial name
- ASC (NCT02625987)
- Testing
- Continuous intradermic stitch, Separated stitches
- Volunteers
- 200 people
- Sponsor
- María Valeria Jiménez Baez
Perforated Appendicitis
Study on Laparoscopic Operation for Perforated Appendicitis
The purpose of this study is to conduct a prospective observational study for the open approach and laparoscopic approach for perforated appendicitis.
- Trial name
- NCT00677989
- Testing
- Laparoscopic appendectomy, Open appendectomy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
NEC
Sensing Oxygen Saturations Using Abdominal NIRS With an Investigational Realtime Device (Songbird)
Preterm infants are highly vulnerable and may suffer from multiple life-threatening conditions that manifest low tissue oxygenation (StO2).
- Trial name
- (Songbird) (NCT05278247)
- Testing
- NIRS
- Volunteers
- 50 people
- Sponsor
- Carag AG
Inguinal Hernia, Postoperative Pain
Safety, Tolerability, PK, and Analgesic Effect of INL-001 in Children Following Open Inguinal Hernia Repair
A multicenter, single-dose study in children 12 to <17 years of age, 6 to <12 years of age, and 2 to <6 years of age who are scheduled for elective open inguinal hernia repair.
- Trial name
- NCT03262688
- Testing
- Bupivacaine HCl collagen-matrix implant, Bupivacaine HCl infiltration
- Where
- 11 sites in United States
- Volunteers
- 159 people
- Sponsor
- Innocoll
Analgesic, Sedative
Analgesic and Sedative Effect of Fentanyl Versus Dexmedetomidine Infusion in Post-Operative Mechanically Ventilated Children After Open Abdominal Surgeries
This study aimed to compare the efficacy and safety of fentanyl versus dexmedetomidine infusion in this population.
- Conditions
- Analgesic, Sedative, Fentanyl, Dexmedetomidine
- Trial name
- NCT06994273
- Testing
- Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Tanta University
Abdominal Pain
Evaluation of S-adenosyl Methionine (SAM-e) for Recurrent Abdominal Pain in Children
This pilot study will investigate the efficacy of SAM-e for the treatment of recurrent abdominal pain in children. This will be an open-labeled study and all participants will receive SAM-e therapy.
- Trial name
- NCT00694564
- Testing
- S-adenosyl methionine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Huang, Jeannie, M.D.
Hernia, Inguinal
Laparoscopic vs Open Hernia Mesh Repair for Inguinal Hernia
This study will determine whether laparoscopic and open hernia repair have the same recurrence and complication rates in the under 60yr old age group. The overall financial costs of each repair will also be compared.
- Trial name
- NCT00311935
- Testing
- method of hernia repair
- Where
- New Zealand
- Volunteers
- 350 people
- Sponsor
- Waitemata District Health Board
Pain, Postoperative, Appendicitis
Choose the Best Concentration of Ropivacaine on TAP Block for Open Appendectomy in Children
Blockage of the transverse abdomen (TAP) promotes excellent analgesia of the abdominal wall and the parietal peritoneum. The TAP block could advange the postoperative pain of Appendectomy in children.
- Trial name
- NCT03005808
- Testing
- Ropivacaine
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil Albert Sabin
Inguinal Hernia
Open and Laparoscopic Hernia Repair. A Comparative Study
A retrospective comparative study in a pediatric surgery center to compare the outcomes of 2 approaches of hernia repair in the pediatric population.
- Trial name
- NCT05011786
- Testing
- hernia repair/ligation of the hernial sac
- Where
- Jordan
- Volunteers
- 155 people
- Sponsor
- Ibrahim Khrais
Appendicitis, Surgery
The Effect of Kinesio Taping in Pediatric Surgery
This study was planned to determine the effect of kinesio taping (KT) applied to the abdominal area after surgery on pain and gas output in children aged 6-12 years who had open appendicitis surgery.
- Conditions
- Appendicitis, Surgery, Pain, Acute
- Trial name
- NCT06344897
- Testing
- Kinesio taping
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- KTO Karatay University
Aneurysm Aortic, Vascular Diseases
F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm
The aim of the present study was to investigate outcomes of a propensity matched series of patients treated with F-BEVAR and open surgery repair for complex abdominal aortic aneurysm in two aortic high-volume centres.
- Trial name
- NCT05247944
- Testing
- Fenestrated and branched endovascular aortic repair (F-BEVAR), Open repair
- Volunteers
- 278 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Appendicitis
Open Appendectomy Versus Laparoscopic Appendectomy
1. Laparoscopic appendectomy may not be a superior procedure when compared with open appendectomy; 2. Various modifications in laparoscopic appendectomy procedure may reduce the technical diffuculty and overall costs.
- Trial name
- NCT01260064
- Testing
- Open appendectomy, Laparoscopic appendectomy with metal endoclips, Laparoscopic appendectomy with suture ligation
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Inguinal Hernia
Hernia Repair Four Arm Comparative Study
This study compares the outcome of the four most commonly used operations for the repair of primary groin hernia including the new key hole surgical techniques.
- Trial name
- NCT00940433
- Testing
- open properitoneal hernia repair, Lechtestien hernia repair, Laparoscopic transperitoneal approach
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- University of Alexandria
Hemorrhage, Soft Tissue Bleeding
The EVARREST® Paediatric Mild/Moderate Liver and Soft Tissue Bleeding Study
The objective of this study is to evaluate the safety and effectiveness of EVARREST™ Sealant Matrix (EVARREST™ Fibrin Sealant Patch) (EVARREST™) in controlling mild or moderate soft tissue \& parenchymal bleeding during open…
- Conditions
- Hemorrhage, Soft Tissue Bleeding, Hepatic Parenchyma Bleeding
- Trial name
- NCT02227992
- Testing
- EVARREST™ Sealant Matrix, SURGICEL®
- Where
- 10 sites in Belgium, United Kingdom
- Volunteers
- 40 people
- Sponsor
- Ethicon, Inc.