Clinical trials: Open Repair
Acute Lung Injury
Human Bronchial Microdialysis in Open Aortic Aneurysm Repair
Elective open aortic aneurysm repair has an overall reported 30 day mortality of 2-6 percent, but in patients more than 65-70 years the mortality is reported to be more than 10 percent.
- Trial name
- NCT01322295
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- Norwegian University of Science and Technology
Inguinal Hernia
Hernia Repair Four Arm Comparative Study
This study compares the outcome of the four most commonly used operations for the repair of primary groin hernia including the new key hole surgical techniques.
- Trial name
- NCT00940433
- Testing
- open properitoneal hernia repair, Lechtestien hernia repair, Laparoscopic transperitoneal approach
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- University of Alexandria
Splenic Artery Aneurysm
Comparison Between Open and Laparoscopic Splenic Aneurysms Repair
The purpose of this study is compare two different surgical treatments of splenic artery aneurysms: open and laparoscopic approach.
- Trial name
- NCT01387828
- Testing
- Laparoscopic splenic aneurysm repair, eventual splenectomy, Laparotomic splenic artery aneurysm repair, eventual artery reconstruction or splenectomy
- Where
- Italy
- Volunteers
- 29 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Dermatitis, Atopic
Locobase® REPAIR Used as an Adjunctive to Standard Therapy in Children With Moderate to Severe Atopic Dermatitis
To assess the efficacy of Locobase REPAIR® when used in children with moderate to severe AD
- Trial name
- NCT00673725
- Testing
- Locobase® REPAIR
- Where
- 3 sites in United Kingdom
- Volunteers
- 49 people
- Sponsor
- Astellas Pharma Europe B.V.
Ataxia Telangiectasia
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside
Study design: Single arm open-label clinical trial in ataxia-telangiectasia to test the effects of nicotinamide riboside on ataxia scales, immune function, and neurofilament light chain.
- Trial name
- ATNAD (NCT06324877)
- Testing
- Nicotinamide riboside
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- The University of Queensland
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Inguinal Hernia
Laparoscopic TEP (Total Extra-peritoneal) Repair Vs Open PHS (Prolene Hernia System)
Abdominal wall hernias are common, with a lifetime risk of 27% in men and 3% in women. Inguinal and femoral hernias are the most common affections faced by primary care physicians that require surgical intervention.
- Trial name
- NCT03842852
- Testing
- Inguinal hernia repair
- Where
- Israel
- Volunteers
- 577 people
- Sponsor
- Assuta Medical Center
Aneurysm Aortic, Vascular Diseases
F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm
The aim of the present study was to investigate outcomes of a propensity matched series of patients treated with F-BEVAR and open surgery repair for complex abdominal aortic aneurysm in two aortic high-volume centres.
- Trial name
- NCT05247944
- Testing
- Fenestrated and branched endovascular aortic repair (F-BEVAR), Open repair
- Volunteers
- 278 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Vascular Aneurysm
French Registry Conducted on E-vita OPEN NEO
Observational, prospective/retrospective, non-randomised, non-comparative, multicentre cohort study. Primary objective is evaluation of in-hospital all-cause mortality after treatment of extensive acute and chronic aortic…
- Trial name
- NEO (NCT05721001)
- Testing
- Surgical Repair
- Where
- 23 sites in France
- Volunteers
- 130 people
- Sponsor
- JOTEC GmbH
Peri-operative Mortality
Open Repair Versus Branched Endograft Repair for Treatment of Residual Chronic Aortic Arch Dissection During Follow-up After Open Type A Acute Ascending Aorta Replacement: Results From an International Multicenter Study.
This study aims to evaluate peri-operative mortality and main post-operative complications (for example cardiovascular, respiratory and renal) in patients treated with frozen elephant trunk techinque.
- Trial name
- NCT04014907
- Testing
- Frozen Elephant Trunk Technique
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Tympanic Membrane Perforation
Perf-Fix Study for Chronic Tympanic Membrane Repair
The purpose of the study is to assess the effectiveness of Perf-Fix as a gel patch to aid in the natural healing process to close chronic, >25% tympanic membrane perforation.
- Trial name
- NCT06083181
- Testing
- Perf-Fix Otologic Gel Patch
- Where
- 7 sites in United States
- Volunteers
- 71 people
- Sponsor
- Tympanogen
Nijmegen Breakage Syndrome
Low Dose Treosulfan Based Conditioning Regimen in HSCT for Nijmegen Breakage Syndrome
The aim of the current study is to evaluate the safety and efficacy of low dose treosulfan based conditioning regimen in HSCT in Nijmegen breakage syndrome
- Trial name
- NCT04400045
- Testing
- Treosulfan
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology