Clinical trials: Operative Surgical Procedures
Acute Uncomplicated Appendicitis
Efficacy of Non Operative Treatment With Amoxicillin/Clavulanic Acid Versus Surgical Treatment in Acute Uncomplicated Appendicitis in Children
The majority of children with uncomplicated acute appendicitis may be considered for either a non-operative or an operative management.
- Trial name
- NACAC (NCT07587450)
- Testing
- Amoxi Clavulanate, appendicectomy
- Where
- 10 sites in France
- Volunteers
- 724 people
- Sponsor
- University Hospital, Toulouse
Acromioclavicular Joint, Dislocation
A Prospective, Randomised Long-term Follow-up of Operative Versus Non-operative Treatment of Gr. 3 Acromioclavicular Dislocation
The purpose of this study is to compare the long-term clinical and radiological results of operative and conservative treatment of Tossy type 3 acromio-clavicular dislocation.
- Conditions
- Acromioclavicular Joint, Dislocation, Surgical Procedures, Operative
- Trial name
- NCT00840593
- Testing
- Non-surgical group, Surgical group
- Where
- Finland
- Volunteers
- 39 people
- Sponsor
- Kuopio University Hospital
Post-operative Nausea, Post-operative Vomiting
Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery
The purpose of this study is to determine whether a multi-modal anesthesia and pain control protocol reduces post-operative and post-discharge nausea and vomiting (PONV and PDNV) in patients undergoing upper jaw corrective…
- Conditions
- Post-operative Nausea, Post-operative Vomiting, Nausea Persistent
- Trial name
- NCT01592708
- Testing
- Antiemetic anesthesia protocol
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- University of North Carolina, Chapel Hill
Non-cardiac Surgery
European Surgical Outcomes Study
The European Surgical Outcomes Study (EuSOS) is a multi-centre, international cohort study of peri-operative care and clinical outcomes for patients undergoing non-cardiac surgery.
- Trial name
- EuSOS (NCT01203605)
- Where
- 28 sites in Belgium, Croatia and 26 more
- Volunteers
- 46,985 people
- Sponsor
- Queen Mary University of London
Airway Management During Operative Procedure
Evaluation of Micropore"s SpiraLith Absorbents
This is an observational study investigating the duration of use and cost of the new CO2 absorbent Micropore's Spiralith®, compared to Drägersorb® 800+, Drägersorb® Free.
- Trial name
- NCT02550470
- Testing
- Carbon Dioxide Absorbents, Micropore SpiraLith, Sevoflurane
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Rutgers, The State University of New Jersey
Bariatric Surgery Candidate
OAGB-MGB Conversions for Post-operative Complications
Laparoscopic mini/one anastomosis gastric bypass (MGB/OAGB) is a relatively new bariatric procedure and is gaining ground over the surgical approach for morbid obesity as a safe and effective operation.
- Trial name
- NCT04641715
- Testing
- OAGB-MGB
- Where
- Italy
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Federico II University
Perforated Eardrum
Inhalational Anesthesia vs TIVA in Endoscopic Tympanoplasty
This study aims to prospectively compare surgical field quality and intraoperative blood loss between general inhalational anesthesia to total intravenous anesthesia (TIVA) alone in subjects undergoing endoscopic ear surgery.
- Trial name
- TIVA (NCT05993039)
- Testing
- Isoflurane Inhalant Product, Sevoflurane inhalant product, Propofol injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Our Lady of the Lake Hospital
Surgical Site Infection (SSI)
Effect of Early vs Late Water Exposure After Cutaneous Surgery
This randomized controlled trial aims to compare the effect of early versus delayed water exposure after cutaneous surgeries on the incidence of surgical site infections.
- Trial name
- NCT07580274
- Testing
- Care as usual
- Volunteers
- 82 people
- Sponsor
- Pak Emirates Military Hospital
Surgical Procedures, Operative, Artificial Intelligence (AI)
Artificial Intelligence in Surgical Practice in Sudan: National Survey of Doctors
This is a national survey of doctors in Sudan who are involved in providing surgical care. The aim is to understand their awareness, experiences, and opinions about using artificial intelligence (AI) in surgery.
- Conditions
- Surgical Procedures, Operative, Artificial Intelligence (AI), Wounds and Injuries, War Injury
- Trial name
- NASAPS (NCT07138105)
- Testing
- National AI in Surgical Practice Survey - Sudan
- Where
- Sudan
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Sudan Medical Specialization Board
Post Surgical Pain
Recovery Toolkits: Assessment of Pragmatic Behavioral Pain Medicine Delivered In Hospital After Surgery
Behavioral pain medicine is largely absent from perioperative pathways, and on post-surgical recovery units. The goal of this project was to develop and implement "Recovery Toolkits", physical branded bags presented to patients…
- Trial name
- NCT03828669
- Testing
- Recovery Toolkits
- Where
- United States
- Volunteers
- 649 people
- Sponsor
- Stanford University
Lung Cancer
Dynamic Monitoring Circulating Tumor DNA in Surgical Patients With Lung Cancer
This study aims to promote the rational use of liquid biopsy in the clinical detection of lung cancer. Lung cancer is a malignant tumor with high morbidity and mortality worldwide.
- Trial name
- LUNGCA (NCT03317080)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- West China Hospital
Lung Cancer
Surgery With or Without Preoperative Chemotherapy in Treating Patients With Resectable Non-small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if surgery is more effective with or without preoperative chemotherapy in treating…
- Trial name
- NCT00003159
- Testing
- carboplatin, cisplatin, docetaxel
- Where
- 2 sites in United Kingdom
- Volunteers
- 600 people
- Sponsor
- Medical Research Council
Breast Neoplasms
Application of Intra-operative Prophylactic Antibiotics/Antiseptics in Chinese Breast Reconstruction Patients
The study aims to investigate different approaches of local application of antibiotics/antiseptics intraoperatively in Chinese patients undergoing post-mastectomy implant based breast reconstruction, and aims to single out an…
- Trial name
- NCT03742908
- Testing
- Cefazolin/clindamycin
- Where
- China
- Volunteers
- 291 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Pharmacological-Aggravated Urticaria
Different Methods of Tranexamic Acid Application in Controlling Peri Operative Bleeding in Gynecomastia Surgery
Different Methods of Tranexamic Acid Application in Controlling Peri-Operative Bleeding in Gynecomastia Surgery
- Trial name
- NCT06509256
- Testing
- Tranexamic acid injection
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemorrhage, Surgical, Tonsillar Bleeding
TEAPOT Study Multisite
After a child has their tonsils removed, sometimes they might bleed which can be a problem. There is a special mist medicine called nebulized tranexamic acid (TXA) that might help stop the bleeding without having to touch the…
- Trial name
- TEAPOT (NCT07565753)
- Testing
- Tranexamic Acid Injectable Product, Normal Saline
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Pain, Acute Post-Operative, Ambulatory Surgical Procedures
Machine Learning-Based Prediction of Postoperative Pain After Pediatric Ambulatory Surgery
This study aims to predict pain after surgery in children of ages 1 to 3 years by using computer programming (machine learning). Participant children will be observed before, during, and after surgery.
- Conditions
- Pain, Acute Post-Operative, Ambulatory Surgical Procedures, Pediatric Pain, Pediatric Patient (1m-21y)
- Trial name
- NCT07274995
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Peer Review, Research
Scheduled Elective Surgical Case Cancellation in Siriraj: Evaluation and Identification of the Reasons
A retrospective cross-sectional analytic study to evaluation and identification of the reasons about Scheduled elective surgical case cancellation in Siriraj Hospital, reason of cancellation will be extracted from hospital…
- Trial name
- NCT02816281
- Where
- Thailand
- Volunteers
- 2,760 people
- Sponsor
- Siriraj Hospital
Patella Dislocation
Conservative Versus Operative - First Time Patella Dislocations
There is no consensus regarding whether rehabilitation or surgical management is best for the management of a primary patellar dislocation.
- Trial name
- NCT05533671
- Testing
- medial patellofemoral reconstruction, Non-operative group
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Atrial Fibrillation
Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery Procedures
The purpose of this study is to determine whether vitamin C is effective in the prophylaxis of post-operative atrial fibrillation in on-pump cardiac surgery
- Trial name
- NCT01107730
- Testing
- Vitamin C, L-Carnitine
- Where
- Greece
- Volunteers
- 33 people
- Sponsor
- Attikon Hospital
Probiotics, Infant, Newborn
Probiotics Supplementation and Intestinal Microbiome in Neonates With Gastrointestinal Surgery
Congenital defects of the gastrointestinal tract commonly require surgical intervention in the neonatal period. Intestinal surgery during this critical period of microbiome acquisition results in aberrant colonization of the…
- Conditions
- Probiotics, Infant, Newborn, Surgical Procedures, Operative, Gastro-Intestinal Disorder
- Trial name
- ProPS (NCT03266315)
- Testing
- FloraBaby
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Calgary