Clinical trials: Operative Wound
Surgery Complications, Surgery
SurgWeek-2: Identifying the Global Burden of Post Operative Complications: an International Prospective Cohort Study Protocol
This study aims to assess and improve the global outcomes following surgery. Every year approximately 313 million operations are performed, with 50 million people experiencing a complication and unfortunately 3.5 million people…
- Conditions
- Surgery Complications, Surgery, Global Surgery, Robotic
- Trial name
- SurgWeek-2 (NCT07785076)
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Bowel Cleansing Prior to Clinical Procedures, Colorectal Anastomosis
Oral Antibiotics vs. No Antibiotics in Pediatric Colorectal Surgery
This study aims to evaluate whether giving oral antibiotics before elective colorectal surgery can improve recovery and reduce complications in children.
- Trial name
- PEACO (NCT07713433)
- Testing
- oral antibiotics, No Oral Antibiotics
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Muhammad Zubair Shoukat
Surgical Site Infection, Surgical Wound Infection
ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions
ROSSINI 2 is a phase III, multi-arm, multi-stage (MAMS) pragmatic, blinded (patient and outcome assessor), multicentre, randomised controlled trial (RCT) with an internal pilot, to evaluate the use of several in-theatre…
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Surgery--Complications, Surgery
- Trial name
- ROSSINI 2 (NCT03838575)
- Testing
- 2% alcoholic chlorhexidine skin prep (SKIN PREP), Iodophor Antimicrobial Incise Drapes (DRAPE), Gentamicin-impregnated implants/ sponges (SPONGE)
- Where
- 2 sites in United Kingdom
- Volunteers
- 6,610 people
- Sponsor
- University of Birmingham
Zygomatic Fractures
A Method of Calculating the Shortest Incision for Internal Fixation of Zygomatic Arch Fracture
In this study, a new method was proposed to calculate the length of sideburns mini incision for zygomatic arch fracture. The purpose of this study was to compare the sideburns mini incision calculated by this method with the…
- Trial name
- NCT05381337
- Testing
- sideburns mini incision, coronal scalp incision
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Wei Jing
Proximal Humerus Fracture
Hanover Humerus Registry
This register study collects data of patients with proximal humerus and humerus shaft fractures to monitor the healing process by assessing shoulder function and quality of life according to the treatment method (operative or…
- Trial name
- HHR (NCT03060876)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Hannover Medical School
Surgical Site Infection
Gaps Between Evidence and Practice in Prevention of Surgical Site Infection in Spain
Web-based survey to members of 10 Spanish Associations of surgical nurses and surgeons of different specialities to know the application of preventative measures for surgical site infection.
- Trial name
- SurveyOIC (NCT04310878)
- Testing
- Survey among perioperative nurses and surgeons
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital de Granollers
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Surgical Site Infection in Obese Women Undergoing C-section
Use of 48 Hour Course of Antibiotics to Prevent Surgical Site Infection in Obese Patients Undergoing Cesarean Delivery
The purpose of this study is to evaluate if preoperative antibiotics, followed by 48 hour course of broad spectrum antibiotics prevents wound infection complications in patients that are obese who undergo cesarean section.
- Trial name
- SSI (NCT01194115)
- Testing
- cephalexin & metronidazole
- Where
- United States
- Volunteers
- 475 people
- Sponsor
- University of Cincinnati
Surgical Site Infections
Ampicillin/Sulbactam Versus Cefuroxime as Antimicrobial Prophylaxis for Cesarean Section
The efficacy and safety of a single dose of ampicillin/sulbactam compared to a single dose of cefuroxime at cord clamp for prevention of postcesarean infectious morbidity has not been assessed.
- Trial name
- NCT01138852
- Testing
- Ampicillin-sulbactam, Cefuroxime
- Volunteers
- 176 people
- Sponsor
- Attikon Hospital
Cubital Tunnel Syndrome
Treatment for Cubital Tunnel Syndrome
The researchers want to find out the best treatment for cubital tunnel. The researchers establish the degree of nerve compression and then the patients are randomised to different treatment alternatives, ranging from conservative…
- Trial name
- NCT00184158
- Testing
- decompression
- Where
- Norway
- Volunteers
- 81 people
- Sponsor
- Norwegian University of Science and Technology
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction
The goal of this clinical trial is to learn whether taking oral tranexamic acid (TXA) for one week after anterior cruciate ligament (ACL) reconstruction improves recovery in adolescents and young adults aged 14 to 25 years.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
- Trial name
- NCT07880743
- Testing
- Tranexamic Acid
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Dave Bernholt
Surgical Procedures, Operative, Artificial Intelligence (AI)
Artificial Intelligence for Surgical Care in War-Torn Sudan: Feasibility, Barriers, and Ethical Perspectives
This study is designed to examine how artificial intelligence (AI) could be applied to support surgical care in Sudan during the ongoing armed conflict.
- Conditions
- Surgical Procedures, Operative, Artificial Intelligence (AI), War Injury, Wounds and Injuries
- Trial name
- NCT07149012
- Testing
- Artificial Intelligence Awareness and Feasibility Assessment
- Where
- Sudan
- Volunteers
- 185 people
- Sponsor
- Sudan Medical Specialization Board
Clavicle Fracture
Supraclavicular Nerve During Clavicle ORIF
Clavicle fractures are a common orthopedic injury and make up 2.6%-5% of all fractures. Despite the benefits of operative management, post-operative chest wall paresthesia is a well-known complication among surgeons and is well…
- Trial name
- NCT06050473
- Testing
- Nerve-sacrificing procedure, Nerve preserving procedure
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Staphylococcus Aureus, Surgical Wound Infection
Risk Factors for Staphylococcus Aureus Surgical Site Infections in Orthopedic and Trauma Surgery
The most commonly identified organism for Surgical Site Infection (SSI) in orthopedic surgery is Staphylococcus aureus but risk factors for mono microbial S.aureus SSI are not well-known.
- Conditions
- Staphylococcus Aureus, Surgical Wound Infection, Orthopedic Disorder, Traumatology
- Trial name
- ISO (NCT03040960)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Cesarean Scar Defect
Double Vers Single in Cesarean Incision
To assess the effect of single versus double layer closure of caesarean scar on the residual myometrium on the short \& intermediate term.
- Trial name
- NCT05276518
- Testing
- Closure of cesarean section incision
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Perforated Eardrum
Inhalational Anesthesia vs TIVA in Endoscopic Tympanoplasty
This study aims to prospectively compare surgical field quality and intraoperative blood loss between general inhalational anesthesia to total intravenous anesthesia (TIVA) alone in subjects undergoing endoscopic ear surgery.
- Trial name
- TIVA (NCT05993039)
- Testing
- Isoflurane Inhalant Product, Sevoflurane inhalant product, Propofol injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Our Lady of the Lake Hospital
Thyroid Disease, Parathyroid Disease
Antimicrobial Prophylaxis in Thyroid and Parathyroid Surgery
The effectiveness of antimicrobial prophylaxis (AMP) for prevention of surgical site infection (SSI) following thyroid and parathyroid surgery remains uncertain.
- Trial name
- Ito-RCT1 (NCT01805856)
- Testing
- PIPC piperacillin sodium, CEZ, cefazolin sodium
- Where
- Japan
- Volunteers
- 2,164 people
- Sponsor
- Ito Hospital
Humerusshaft Fractures
Non Randomized Humerusshaft Fracture
The aim of the study is to radiologically compare the fracture healing as well as the functional treatment outcome of conservative and operative treatment of defined humerusshaft fractures after 6w./12w./and 12 month based on the…
- Trial name
- NCT00205972
- Testing
- Humerus Nail or LC Plate
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Facial Bones Fracture
Evaluation of Safety and Efficacy of Nasea(R)/Ramosetron Inj. in Patients Undergoing Facial Bone Fracture Operations
Postoperative nausea and vomiting (PONV) is one of the most common and distressing complications after anaesthesia and surgery, and may lead to serious postoperative complications This prospective, randomized study designed to…
- Trial name
- NCT01637545
- Testing
- Ramosetron
- Where
- South Korea
- Volunteers
- 49 people
- Sponsor
- Seoul National University Hospital
Inguinal Hernia
A Prospective Study Comparing Telescopic vs. Balloon Dissection in Single Incision Laparoscopic Inguinal Herniorraphy (SILTELESCOPIC)
Our recent prospective randomized controlled study comparing single-port vs. multiport laparoscopic total extraperitoneal inguinal herniorraphy (NCT 01660048) demonstrated superiority of the single-port technique in reducing…
- Trial name
- SILTelescopic (NCT01883115)
- Where
- 2 sites in Australia
- Volunteers
- 102 people
- Sponsor
- The Sydney Hernia Specialists Clinic