Clinical trials: Ophthalmopathy
Entropion
Cicatricial Upper Eyelid Entropion Management
Suture-less technique will be used in treatment for cicatricial upper eyelid entropion to detect its long-term efficacy
- Trial name
- NCT05371626
- Testing
- Suture-less surgical procedure
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Primary Congenital Glaucoma
Long Term Evaluation of Primary Congenital Glaucoma Management in Sohag University Hospital
evaluation of primary congenital glaucoma management in sohag university hospital
- Trial name
- PCG (NCT04949555)
- Testing
- Primary congenital glaucoma evaluation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Refractive Errors
The Effect of Gabapentin (Neurentin) and Pregabalin (Lyrica) in Pain Reduction After Photorefractive Keratectomy
The studied patients will be given randomly one of three following drugs1:Gabapentin2: Pregabalin or placebo for 3 days after Photorefractive keratectomy surgery.
- Trial name
- PRK (NCT01122004)
- Testing
- Pregabalin
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Vernal Keratoconjunctivitis
Double-Masked Trial of NOVA22007 (1mg/mL Ciclosporin/Cyclosporine) Versus Vehicle in Pediatric Patients With Active Severe Vernal Keratoconjunctivitis
The objective of this study is to compare the efficacy of two different dosing regimen of NOVA22007 (1mg/ml ciclosporin/cyclosporine) eye drops, emulsion versus placebo (vehicle of the formulation) administered four times a day…
- Trial name
- NCT01751126
- Testing
- NOVA22007 ''Ciclosporin''
- Where
- 46 sites in United States, Croatia and 9 more
- Volunteers
- 169 people
- Sponsor
- Santen SAS
Blindness
Enhanced Tactile Memory in the Blind
This study will determine if the brain regions in blind people that would normally be involved in vision are used instead to remember touch.
- Trial name
- NCT00076700
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Amblyopia
Prospective Evaluation of a Smartphone Application, GoCheckKids™, to Detect Amblyopia Risk Factors in Young Children
The objective is evaluation of GoCheck Kids, a smartphone application ('App'), for use as a photo screening device in a pediatric population to detect amblyopia risk factors (ARFs).
- Trial name
- NCT03447171
- Testing
- App Vision Screening
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- Gobiquity Mobile Health
Myopia
Assessment of Lotrafilcon A Contact Lenses
The purpose of this 3-month study is to evaluate subjective responses to an upgraded contact lens.
- Trial name
- NCT01185834
- Testing
- Lotrafilcon A upgrade soft contact lens
- Volunteers
- 118 people
- Sponsor
- CIBA VISION
Myopia
Non-dispense Comfort Comparison of Two Silicone Hydrogel Lenses
The purpose of this study is to compare subjective responses to two contact lenses after 15 minutes of wear.
- Trial name
- NCT00808834
- Testing
- Lotrafilcon A contact lens, Senofilcon A contact lens
- Volunteers
- 196 people
- Sponsor
- CIBA VISION
Ophthalmic Diseases (Specific Types Not Restricted), Cataract
Research on a New Intelligent Mobile Screening and Diagnosis Pattern for Ocular Diseases
The global distribution of primary ophthalmic medical resources is uneven, and the traditional eye disease screening model has problems such as low efficiency, high cost and limited coverage.
- Conditions
- Ophthalmic Diseases (Specific Types Not Restricted), Cataract, Refraction Error, Diabetic Retinopathy (DR)
- Trial name
- NCT07003165
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Dry Eye Syndromes
Comparison Of Blue Light Filter Feature and Blue Blocking Lenses in Digital Device Users With Dry Eye Patients
Comparing Blue Light Filter feature and Blue Blocking Lenses for Dry Eye Patients Prolonged screen time can exacerbate dry eye symptoms.
- Trial name
- NCT06913504
- Testing
- Blue cut filter, blue cut glasses
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Superior University
Pediatric Glaucoma, Elevated IOP in Pediatric Patients
Study of Travoprost Ophthalmic Solution, 0.004% Compared to Timolol (0.5% or 0.25%) in Pediatric Glaucoma Patients
The purpose of this study is to evaluate the intraocular pressure (IOP)-lowering efficacy of Travoprost 0.004% POLYQUAD (PQ) ophthalmic solution compared to Timolol ophthalmic solution (0.5% or 0.25%) in pediatric glaucoma…
- Conditions
- Pediatric Glaucoma, Elevated IOP in Pediatric Patients, Ocular Hypertension in Pediatric Patients
- Trial name
- NCT01652664
- Testing
- Travoprost 0.004% PQ ophthalmic solution, Timolol, 0.5% or 0.25% ophthalmic solution, Travoprost Vehicle
- Volunteers
- 184 people
- Sponsor
- Alcon Research
Myopia, Visual Fatigue
Impact of Various Myopia Management Strategies on Asthenopia Among Pediatric and Adolescent Populations
Different myopia control interventions have certain effects on ocular asthenopia in children and adolescents. As children and adolescents are in a critical period of visual development, the presence of asthenopia may lead to an…
- Trial name
- NCT07691671
- Volunteers
- 600 people
- Sponsor
- Tianjin Medical University Eye Hospital
Retinal Detachment
Internal Limiting Membrane Flaps for Coexistent Macular Hole and Retinal Detachment
Purpose: To evaluate the logical surgical approaches in closing macular holes in eyes of proliferative diabetic retinopathy with retinal detachment
- Trial name
- ILMFCMHRDPDR (NCT03618498)
- Testing
- ILM flaps insertion techniques or free ILM flaps.
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Changhua Christian Hospital
Myopia
Efficacy of Myopia-control Lenses in a Population of Young Adults : the OPTIMA Study
The goal of this clinical trial is to learn if myopia-control eyeglass lenses (Essilor® Stellest® 2.0) can slow down the progression of short-sightedness (myopia) in young adults, compared with standard single-vision lenses.
- Trial name
- OPTIMA (NCT07804043)
- Testing
- Essilor® Stellest® 2.0 myopia-slowing lenses, Standard lenses
- Where
- France
- Volunteers
- 134 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
WAGR Syndrome, Wilm's Tumor
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions
This study will explore conditions caused by the absence of certain genes on chromosome 11. These conditions include WAGR syndrome, which is characterized by a kidney tumor called Wilm s tumor, aniridia (absence of the iris of…
- Conditions
- WAGR Syndrome, Wilm's Tumor, Aniridia, Urogenital Abnormalities
- Trial name
- NCT00758108
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pterygium
A Comparison Between Surgical Techniques for Securing Conjunctival Autografting in Primary Pterygium Surgery
Pterygium is a fibrovascular wing shaped encroachment of conjunctival fold on to the cornea with elastotic degeneration of a subconjunctival tissue, The standard treatment for pterygium is surgical excision, but the recurrence…
- Trial name
- NCT03301974
- Testing
- conjunctival autograft with fibrin glue, sutured conjunctival autograft, sutureless and glue-free conjunctival autograft
- Volunteers
- 60 people
- Sponsor
- Assiut University
MGD-Meibomian Gland Dysfunction, Positron-Emission Tomography
PET-CT Imaging Features of Meibomian Glands
Analysis the results of Dry eye analysis results and PET-CT imaging comprehensively
- Conditions
- MGD-Meibomian Gland Dysfunction, Positron-Emission Tomography, Dry Eye
- Trial name
- NCT06324890
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Myopia
Clinical Investigation of Buttermere (LENS 271) Soft Contact Lenses
The purpose of the study is to compare clinical performance between two soft contact lenses.
- Trial name
- NCT06609018
- Testing
- Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
- Where
- United Kingdom
- Volunteers
- 73 people
- Sponsor
- CooperVision, Inc.
Myopia, Progressive, Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression
This is a monocenter, randomized, controlled, parallel-group, double-masked clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation at baseline compared to a…
- Trial name
- NCT05331378
- Testing
- Test myopia control lenses, Single vision lenses
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Essilor International
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