Clinical trials: Opioid Use After Surgery
Cholelithiasis, Postoperative Pain, Laparoscopic Cholecystectomy
ESP vs Subcostal TAP Block for Analgesia After Laparoscopic Cholecystectomy
This prospective, randomized, double-blind study compares the analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and subcostal transversus abdominis plane (TAP) block in patients undergoing laparoscopic…
- Trial name
- ESP TAP (NCT07661693)
- Testing
- Erector Spinae Plane Block, Subcostal Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gaziantep City Hospital
Postoperative Pain, Acute, Opioid Use
Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation After Labrum Repair
The purpose of this study is to determine if patients age 15 to 30 years old being treated for shoulder labrum repair and SLAP lesions have significant differences in pain levels postoperatively when treated with a combination…
- Conditions
- Postoperative Pain, Acute, Opioid Use, Labral Tear, Glenoid
- Trial name
- NCT05974423
- Testing
- Tylenol, Ibuprofen, and Oxycodone, Tylenol and Ibuprofen only
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cooper Health System
Opioid Use, Unspecified
Investigating Interventions to Reduce Residual Opioids in the Home Following Legitimate Opioid Prescribing in Children.
The overall objective of this study is to evaluate strategies to reduce unused opioids prescribed for pediatric acute post-surgical pain management.
- Trial name
- NCT04219397
- Testing
- Medication take back, Medication home disposal
- Where
- 2 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Indiana University
Post Operative Pain, Analgesia
Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years
During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist.
- Conditions
- Post Operative Pain, Analgesia, Children, Only, Narcotic Use
- Trial name
- NCT05758090
- Testing
- NIPE monitor, Control
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Pain, Postoperative, Medication Adherence
Scenario Tailored Opioid Messaging Program (STOMP) to Improve Risk Understanding in Young Adults
Legitimate prescription opioid use during adolescence has been associated with later prescription opioid misuse and substance use disorder symptoms during adulthood.
- Conditions
- Pain, Postoperative, Medication Adherence, Opioid Use, Knowledge, Attitudes, Practice
- Trial name
- STOMPYA (NCT03863353)
- Testing
- Educational Intervention
- Where
- 2 sites in United States
- Volunteers
- 503 people
- Sponsor
- University of Michigan
Pain, Postoperative, Orthognathic Surgery
Personalization of Opioid Prescription Following Orthognathic Surgery
This study aims to investigate pain management and satisfaction following orthognathic surgery, which is a type of surgery that corrects jaw and facial bone issues.
- Conditions
- Pain, Postoperative, Orthognathic Surgery, Opioid Use, Patient Satisfaction
- Trial name
- NCT05708521
- Testing
- Personalization of dose and frequency and instituting a tapering protocol of hydromorphone post-orthognathic surgery, Standardized dose and frequency of hydromorphone with no tapering post-orthognathic surgery
- Where
- Canada
- Volunteers
- 201 people
- Sponsor
- Nova Scotia Health Authority
Adenotonsillectomy, Post-operative Analgesia
Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy
The goal of this study is to determine if non-opioid pain control is a safe way to manage pain after intracapsular adenotonsillectomy surgery in children.
- Conditions
- Adenotonsillectomy, Post-operative Analgesia, Opioid Use
- Trial name
- NCT04791761
- Testing
- Oxycodone, Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- David Chi, MD
Postoperative Pain, Opioid Use
Dexmedetomidine Use in SZMN Blocks for Pediatric T&A Pain Control
The suprazygomatic maxillary nerve (SZMN) block is a well-established, safe and effective regional technique for pain management following cleft palate procedures.
- Trial name
- NCT05208892
- Testing
- SZMN block, SZMN block with Dexmedetomidine
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Stanford University
Constipation
Methylnaltrexone Use for Opioid-induced Postoperative Constipation
The purpose of this study is to determine whether the routine use of methylnaltrexone in the post-operative pediatric spinal fusion patient will decrease the incidence of constipation.
- Trial name
- NCT01773096
- Testing
- Methylnaltrexone, Senna, docusate sodium, bisacodyl, magnesium hydroxide, Miralax
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shriners Hospitals for Children
Pain Management
Family Experience of Home Opioid Use After Pediatric Surgery
A systematic review examining outpatient opioid use identified only three pediatric studies published between 2015 and 2016. Of these three, two studies had a short-term follow up with patients at three days after discharge…
- Trial name
- NCT03562013
- Where
- Canada
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Pain, Postoperative
Opioids Following ACL
The purpose of this study is to evaluate the effectiveness of a post-operative opioid pain 18 management protocol for anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT04278703
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Rothman Institute Orthopaedics
Opioid Use, Pain, Postoperative
Effect of Battlefield Acupuncture and Physical Therapy Versus Physical Therapy Alone After Shoulder Surgery
The purpose of this randomized clinical trial is to determine the effectiveness of Battlefield Acupuncture (BFA) in addition to usual post-surgical shoulder physical therapy compared to a standard shoulder rehabilitation program…
- Conditions
- Opioid Use, Pain, Postoperative, SLAP Lesion, Bankart Lesion
- Trial name
- NCT03525275
- Testing
- Battlefield Acupuncture, Post-surgical shoulder protocol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Keller Army Community Hospital
Pain, Postoperative
Opioid & Steroid Use Following Tonsillectomy in Pediatric Patients
The purpose of this study is to determine if a post-operative course of oral dexamethasone affects opioid usage in pediatric patients undergoing tonsillectomy.
- Trial name
- NCT04541147
- Testing
- Dexamethasone, Analgesics
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Pain, Postoperative
Magnesium as an Adjuvant Agent for Postoperative Pain
Participants are being asked to participate in this research study because they have elected to undergo periacetabular osteotomy (PAO).
- Trial name
- NCT05947760
- Testing
- IV Magnesium Sulfate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University Hospitals Cleveland Medical Center
Surgery, Opioid Use
Increasing Implementation of Post-Operative Opioid Prescribing Guidelines
The objective of this research study is to evaluate the effect of a quality improvement initiative carried out by a health system opioid stewardship task force aiming to increase clinician post-operative prescribing adherence…
- Conditions
- Surgery, Opioid Use, Opioid Misuse, Prescription Opioid Misuse
- Trial name
- NCT05358522
- Testing
- Opioid Prescribing Report Cards
- Where
- United States
- Volunteers
- 26,562 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Opioid Use, Post Operative Pain
Assessment of the Development of Postoperative Persistent Postoperative Pain
During the postoperative period, it is possible to observe the development of acute pain, which lasts no longer than a week after surgery.
- Conditions
- Opioid Use, Post Operative Pain, Chronic Pain
- Trial name
- NCT05370924
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Opioid Use, Post-thoracotomy Pain Syndrome
Serratus Anterior Plane Block for Management of Post Thoracotomy Pain
This is a single-center, randomized, prospective study evaluating the effect of serratus anterior plane block performed after induction of anesthesia, but before the start of surgery on postoperative opioid requirements.
- Conditions
- Opioid Use, Post-thoracotomy Pain Syndrome, Local Anaesthetic Agent Overdose, Local Anesthetic Complication
- Trial name
- SAPB (NCT04258436)
- Testing
- Serratus anterior block
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Tonsillitis, Sleep Disordered Breathing
Opioid Use, Storage, and Disposal Among Pediatric Patients After Surgery
Opioids are an important component of post-operative pain management among children, but are often prescribed in excess and rarely disposed of appropriately.
- Conditions
- Tonsillitis, Sleep Disordered Breathing, Hernia, Hydrocele
- Trial name
- NCT03575377
- Testing
- Disposal Aid
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Nationwide Children's Hospital
Post-operative Pain, Opioid Use
QL vs LAI for Palatoplasty
This study will consist of patients ages 6-18 who are undergoing a surgery on the hard or soft palate of the mouth (palatoplasty), with removal of bone from the front of the hip (anterior iliac bone graft harvesting).
- Conditions
- Post-operative Pain, Opioid Use, Cleft Palate
- Trial name
- NCT06420336
- Testing
- Quadratus lumborum block, Local anesthetic infiltration
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Medical University of South Carolina
Pain, Postoperative, Pain
The Adolescent Surgery Experience: A Mixed Methods Analysis
New chronic pain and opioid use are reported as prevalent among adolescents undergoing major surgery; many unanswered questions remain regarding recovery and the anticipated pain trajectory across procedures and the interaction…
- Conditions
- Pain, Postoperative, Pain, Pain, Acute, Pain, Chronic
- Trial name
- NCT05482919
- Testing
- Baseline Survey, Post Operative Surveys, Qualitative Interviews
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Children's Hospital of Philadelphia