Clinical trials: Opioid Use After Surgery
Opioid Use, Post-thoracotomy Pain Syndrome
Serratus Anterior Plane Block for Management of Post Thoracotomy Pain
This is a single-center, randomized, prospective study evaluating the effect of serratus anterior plane block performed after induction of anesthesia, but before the start of surgery on postoperative opioid requirements.
- Conditions
- Opioid Use, Post-thoracotomy Pain Syndrome, Local Anaesthetic Agent Overdose, Local Anesthetic Complication
- Trial name
- SAPB (NCT04258436)
- Testing
- Serratus anterior block
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Adenotonsillectomy, Post-operative Analgesia
Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy
The goal of this study is to determine if non-opioid pain control is a safe way to manage pain after intracapsular adenotonsillectomy surgery in children.
- Conditions
- Adenotonsillectomy, Post-operative Analgesia, Opioid Use
- Trial name
- NCT04791761
- Testing
- Oxycodone, Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- David Chi, MD
Postoperative Pain, Opioid Use
SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A
The suprazygomatic maxillary nerve (SZMN) block is a well-established, safe and effective regional technique for pain management following cleft palate procedures, however, have not been studied for patients undergoing…
- Trial name
- SZMN (NCT04797559)
- Testing
- SZMN Block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Opioid Use, Pain, Postoperative
ESP Block in Pediatric Patients for Postoperative Analgesia
Pediatric cardiac surgery is associated with moderate to severe postoperative pain that is related to median sternotomy. In a fast-track protocol, used in modern-day cardiac surgical care, early extubation may be facilitated by…
- Conditions
- Opioid Use, Pain, Postoperative, Quality of Life
- Trial name
- ESP1 (NCT03627897)
- Testing
- Bupivacain, saline
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cukurova University
Pain, Postoperative
Effect of Gabapentin on Postoperative Opioid Analgesic Use and Pain in Adolescents Undergoing Tonsillectomy
This study aims to determine if administration of gabapentin preoperatively followed by a standing postoperative course is effective in reducing and possibly eliminating the use of opioid analgesics following this procedure.
- Trial name
- NCT05024825
- Testing
- Gabapentin, hydrocodone, acetaminophen and ibuprofen
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Moderate to Severe Acute Postoperative Pain
Use of Tapentadol Oral Solution for Pain After Surgery in Children From Newborn to Less Than 2 Years Old
This is a multicenter, open-label (all people involved know the identity of the intervention), single dose trial to evaluate the pharmacokinetic (PK) profile (how drugs are absorbed in the body, how are they distributed within…
- Trial name
- NCT02221674
- Testing
- Tapentadol
- Where
- 7 sites in United States, Poland and 1 more
- Volunteers
- 40 people
- Sponsor
- Grünenthal GmbH
Pain Management
Family Experience of Home Opioid Use After Pediatric Surgery
A systematic review examining outpatient opioid use identified only three pediatric studies published between 2015 and 2016. Of these three, two studies had a short-term follow up with patients at three days after discharge…
- Trial name
- NCT03562013
- Where
- Canada
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Pain, Postoperative
Opioids Following ACL
The purpose of this study is to evaluate the effectiveness of a post-operative opioid pain 18 management protocol for anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT04278703
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Rothman Institute Orthopaedics
Opioid Use, Unspecified
Methadone vs. Fentanyl Administration on Postoperative Pain Control in Pediatric Patients Undergoing Cardiac Surgery
The purpose of this study is to determine if methadone improves postoperative pain control in pediatric patient's undergoing cardiac surgery.
- Trial name
- CV_RCT_M_F (NCT02747875)
- Testing
- Methadone, Fentanyl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Andrew Waberski
Opioid Use, Post Operative Pain
Assessment of the Development of Postoperative Persistent Postoperative Pain
During the postoperative period, it is possible to observe the development of acute pain, which lasts no longer than a week after surgery.
- Conditions
- Opioid Use, Post Operative Pain, Chronic Pain
- Trial name
- NCT05370924
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Pain, Postoperative
Opioid & Steroid Use Following Tonsillectomy in Pediatric Patients
The purpose of this study is to determine if a post-operative course of oral dexamethasone affects opioid usage in pediatric patients undergoing tonsillectomy.
- Trial name
- NCT04541147
- Testing
- Dexamethasone, Analgesics
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Postoperative Pain, Acute, Opioid Use
Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation After Labrum Repair
The purpose of this study is to determine if patients age 15 to 30 years old being treated for shoulder labrum repair and SLAP lesions have significant differences in pain levels postoperatively when treated with a combination…
- Conditions
- Postoperative Pain, Acute, Opioid Use, Labral Tear, Glenoid
- Trial name
- NCT05974423
- Testing
- Tylenol, Ibuprofen, and Oxycodone, Tylenol and Ibuprofen only
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cooper Norcross Health
Pain, Postoperative, Opioid Use
Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis
Pediatric spinal fusion (PSF) surgery is a painful procedure that can treat adolescent idiopathic scoliosis (AIS). One technique that can potentially reduce patients' pain levels and need for opioid medication is the…
- Conditions
- Pain, Postoperative, Opioid Use, Recruitment
- Trial name
- NCT04500613
- Testing
- Bilateral Erector Spinae Plane Block with bupivacaine and dexamethasone, No bilateral Erector Spinae Plane Block (no bupivacaine and no dexamethasone)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative, Premature Infant
Postoperative Pain Control & Relief in Neonates
Pain control for newborns has made significant improvements over the last 30 years. The use of narcotics remains the standard of care for neonates undergoing minor and major surgeries.
- Conditions
- Pain, Postoperative, Premature Infant, Opioid Use
- Trial name
- POPCORN (NCT03677830)
- Testing
- Acetaminophen, Saline
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children
Evaluation of Pain Management After Surgery When Using Nerve Blocks in the Pediatric Population
The goal of this randomized clinical trial is to determine if single-shot ropivacaine peripheral nerve blocks (PNB - perineural injections) for anterior cruciate ligament (ACL) reconstruction procedures in pediatric orthopaedic…
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Trial name
- NCT06559137
- Testing
- Ropivacaine 0.2% Injectable Solution
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Postoperative Pain, Opioid Use
Dexmedetomidine Use in SZMN Blocks for Pediatric T&A Pain Control
The suprazygomatic maxillary nerve (SZMN) block is a well-established, safe and effective regional technique for pain management following cleft palate procedures.
- Trial name
- NCT05208892
- Testing
- SZMN block, SZMN block with Dexmedetomidine
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Stanford University
Pain, Postoperative, Pain
The Adolescent Surgery Experience: A Mixed Methods Analysis
New chronic pain and opioid use are reported as prevalent among adolescents undergoing major surgery; many unanswered questions remain regarding recovery and the anticipated pain trajectory across procedures and the interaction…
- Conditions
- Pain, Postoperative, Pain, Pain, Acute, Pain, Chronic
- Trial name
- NCT05482919
- Testing
- Baseline Survey, Post Operative Surveys, Qualitative Interviews
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Children's Hospital of Philadelphia
Pain, Postoperative
Magnesium as an Adjuvant Agent for Postoperative Pain
Participants are being asked to participate in this research study because they have elected to undergo periacetabular osteotomy (PAO).
- Trial name
- NCT05947760
- Testing
- IV Magnesium Sulfate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University Hospitals Cleveland Medical Center
Post Operative Pain, Analgesia
Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years
During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist.
- Conditions
- Post Operative Pain, Analgesia, Children, Only, Narcotic Use
- Trial name
- NCT05758090
- Testing
- NIPE monitor, Control
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Pain, Pediatric Cancer
An English/Spanish Mobile Augmented Reality Pain Assessment App for Hispanic/Latino Pediatric Cancer Patients
In this SBIR, ALTality, Inc. ("SpellBound") will assess the feasibility of a dual English/Spanish language augmented reality(AR)-enabled tool for assessing inpatient postoperative pain/nausea/vomiting in Hispanic/Latino children…
- Trial name
- NCT06635434
- Testing
- AR Pain assessment
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- ALTality, Inc.