Clinical trials: Optical Coherence Tomography
Sickle Cell Retinopathy
New, Previously Unknown, Uses of Optical Coherence Tomography Angiography (OCTA)
Sickle cell maculopathy was sparingly mentioned in the literature before despite the fact that sickle cell disease or sickle cell trait is common in people of many areas of the world.
- Trial name
- OCTA (NCT03068702)
- Testing
- Optical Coherence Tomography Angiography
- Volunteers
- 2 people
- Sponsor
- Dr. S.S. Michel Clinic
Aphakia
Intraocular Position of Secondary Iris-Fixated IOLs in Aphakic Eyes
The purpose of this study is to evaluate the intraocular stability and safety of secondary iris-fixated IOLs in aphakic patients.
- Trial name
- NCT00773266
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Capsule Opacification, Tissue Adhesions
Evaluate Capsular Apposition to Intraocular Lens
In this study, the investigators examined the capsule-IOL interaction including anterior and posterior capsule adhesion, contact between posterior capsule and the posterior edge of intraocular lense (IOL), configuration of…
- Conditions
- Capsule Opacification, Tissue Adhesions, Aphakia - Lens Capsule Present, Opacification of Intraocular Lens
- Trial name
- NCT01605812
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Wenzhou Medical University
Retinitis Pigmentosa
Study of the Correlation Between Macular Thickness Analyzed by Optical Coherence Tomography and the Visual Functions in Retinitis Pigmemtosa
Purpose: To study the associations between visual functions and the retinal tomography detected by optical coherence tomography (OCT) in patients with retinitis pigmentosa (RP).
- Trial name
- NCT00784901
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Intermittent Exotropia
Lateral Rectus Muscle and Anterior Segment Optical Coherence Tomography (AS-OCT) in Two Recession Surgeries
Background and study aims : The investigators conducted this study to compare the movement of extraocular muscle after two types of recession surgery with non-invasive tool called AS-OCT.
- Trial name
- AS-OCT (NCT02450162)
- Testing
- lateral rectus recession (bilateral)
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Pregnancy
Evaluation of Choroidal Thickness During Pregnancy Using Enhanced Depth Imaging Optical Coherence Tomography
The purpose of this study is to evaluate choroidal thickness and volume during the third trimester of pregnancy by comparison with a group of age-matched non-pregnant healthy group of women
- Trial name
- NCT02024048
- Testing
- OCT
- Where
- Portugal
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Gaia Hospital
Congenital Heart Disease, Children, Only
Optical Coherence Tomography Angiography (OCTA) in Children's Cardiac Surgery
Around 3500 children including 1,000 babies a year in the UK require heart surgery. Open-heart repairs involve the heart being stopped, while blood is pumped around the body using a cardiopulmonary bypass machine.
- Trial name
- OCTA (NCT05568849)
- Testing
- OCTA measurements
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Chronic Coronary Syndrome, Coronary Artery Disease
Feasibility of a Deep Learning-based Algorithm for Non-invasive Assessment of Vulnerable Coronary Plaque
The primary objective of this study is to assess the accuracy in terms of sensitivity, specificity, negative and positive predicted values of the DL-based algorithm with respect to correct identification of the plaque and…
- Conditions
- Chronic Coronary Syndrome, Coronary Artery Disease, Stable Angina, Acute Coronary Syndrome
- Trial name
- FOCUS DL (NCT06186336)
- Testing
- Deep Learning-based Vulnerable Plaque Detection and Assessment Tool
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- GE Healthcare
Environmental Enteric Dysfunction
Capsule Endomicroscopy for Visualization of the Small Intestine in EED Population in Pakistan
This pilot study will test the feasibility and tolerability of the tethered OCT capsule and Trans Nasal Endomicroscopy probe and accessory devices for imaging the small intestine in subjects with EED and a matched non-EED cohort.
- Trial name
- NCT04275167
- Testing
- Tethered Capsule Endomicroscope/Trans Nasal Endomicroscope
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cataract
Anterior Capsule Polishing Effect on Effective Lens Position
The purpose of this study is to evaluate effects of anterior capsule polishing on effective lens position (ELP) and actual axial movement of the intraocular lens (IOL) by measuring anterior chamber depth (ACD) patients with…
- Trial name
- NCT01598428
- Testing
- anterior capsule polishing
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shandong University
Vascular Stains
Multicenter Phenotype-Genotype Analysis of Vascular Stains to Optimize Treatment Utilizing Optical Coherence Tomography
The purpose of this research study is to develop a better understanding of vascular stains and to improve the usual laser treatment for vascular stain by using optical coherence tomography (OCT).
- Trial name
- NCT04772911
- Testing
- Optical Coherence Tomography (OCT)
- Where
- 2 sites in United States
- Volunteers
- 73 people
- Sponsor
- University of Wisconsin, Madison
Retinal Diseases, Optic Nerve Diseases
Spectral Domain Optical Coherence Tomography Imaging of the Eyes of Neonates
Brief Summary The purpose of this study is to better characterize the retina and optic nerve in newborns using spectral domain optical coherence tomography (s-oct).
- Trial name
- OCT (NCT01404247)
- Testing
- Observational: to better characterize the retina and optic nerve in newborns using spectral domain optical coherence tomography (s-oct)., OCT imaging.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Otitis Media Acute
Otitis Treatment With OtoSight™ - Modification of Antibiotic Treatment Intervention in Children
A pragmatic, mixed-method trial is to show the ability of OtoSight to change management of the pediatric patient presenting with ear pain in a way that improves patient outcomes and reduces costs.
- Trial name
- OTO-MATIC (NCT06285812)
- Testing
- OtoSight Middle Ear Scope
- Where
- 7 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- PhotoniCare, Inc.
Deprivation Amblyopia
OCTA Analysis In Children After Lensectomy
The aim of this study is to quantify and compare the foveal avascular zone (FAZ), the parafoveal and foveal vessel density of superficial (SCP) and deep capillary plexus (DCP) and retinal thickness in deprivation amblyopic eyes…
- Trial name
- NCT04217772
- Testing
- Optical Coherence Tomography Angiography
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Multiple Sclerosis
Oct-A and Perimetry in Multiple Sclerosis
This study aims to assess retinal vascular density using OCT-A and correlate these parameters with visual field changes in MS patients with and without a history of ON
- Trial name
- MS (NCT07175324)
- Testing
- optical coherence tomography angiography, Visual Field Perimetry
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Assiut University
Retinal Dystrophies
SS-HH-OCT as a Novel Diagnostic Modality for Early-Onset Retinal Dystrophies (EORDs)
The goal of this observational study is to utilize a novel imaging system designed for high-resolution retinal imaging of neonates, infants and children to identify the signs of photoreceptor development and degeneration in…
- Trial name
- SS-HH-OCT (NCT06177977)
- Testing
- SS-HH-OCT
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Duke University
AMD - Age-Related Macular Degeneration
Comparison of the Sensibility of Swept Source Optical Coherence Tomography Devices in the Detection of Neovascularisation in Large Pigment Epithelium Detachments
The goal of this observational study is to compare swept source optical coherence tomography devices ability to detect macular neovascularisation when there is a large pigment epithelium detachment higher than 250 microns
- Trial name
- NCT07143526
- Testing
- Optical Coherence Tomography Angiography (OCT-A)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University of Trieste
Keratoconus, Corneal Opacity
OCT in Diagnosis of Irregular Corneas
This main goal of this study is to improve the detection, classification, monitoring, and treatment of irregular corneas due to keratoconus, warpage, dry eye, scar, stromal dystrophies, and other corneal conditions.
- Conditions
- Keratoconus, Corneal Opacity, Corneal Dystrophy
- Trial name
- NCT03504800
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University