Clinical trials: Oral Mucositis
Aphthous Stomatitis
Safety, Galenic Acceptability and Efficacy of GV-328 Lozenges in Children With Oral Aphthosis
The aim of the study was to assess the safety, acceptability, and efficacy of product GV-328 for the treatment of childhood oral aphthous lesion.
- Trial name
- NCT04677062
- Testing
- GV-328
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Aphthous Stomatitis
Efficacy and Safety of BALI Association in the Treatment of Aphthous Ulcerations
The purpose of this study is to evaluate the efficacy and safety of BALI association in the treatment of aphthous ulceration.
- Trial name
- NCT05542173
- Testing
- BALI association
- Where
- Brazil
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- EMS
Oral Aphthous Ulcer
Clinical Evaluation of Topical Coenzyme Q10 in Management of Oral Aphthous Ulcer
Recurrent oral aphthous ulcer is the most common oral lesion in occurrence and one of cause is oxidative stress so investigators need to use antioxidant drugs like topical coenzyme Q10 gel to treat the lesion and more safe for…
- Trial name
- NCT03213769
- Testing
- topical coenzyme Q10 gel, Carpabol gel
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peri-implant Mucositis, Peri-Implantitis
Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical
Bleeding on probing (0,1,2,3), plaque index (+,-) and pocket probing depth will be recorded for each visit. Before the procedure, the patient will be randomly assigned to one of four groups and records will be kept.
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Bleeding on Probing, Periodontal Pocket
- Trial name
- NCT06287957
- Testing
- Labrida BioClean, EMS Handy 3.0 Perio Premium
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Recurrent Aphthous Ulcer, Recurrent Aphthous Stomatitis
Effectiveness of Recurrent Aphthous Stomatitis Mouthwash System for the Treatment of Oral Ulcers
The purpose of the present research is to evaluate the efficacy of a gel formulation for a total treatment of 14 days for the treatment of traumatic or aphthous oral ulcers.
- Trial name
- RASMA (NCT07121361)
- Testing
- Mouthwash Product, Control
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Minor Recurrent Aphthous Stomatitis Lesions
The Effect of 2-DeNT Oral Topical Powder on Minor Recurrent Aphthous Ulcer
This is a prospective, randomized, blinded, placebo-controlled, crossover clinical trial to evaluate the efficacy of 2-DeNT oral topical powder in the treatment of recurrent aphthous stomatitis (RAS).
- Trial name
- NCT02142543
- Testing
- 2-DeNT powder
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Peri-Implant Health, Peri-Implantitis and Peri-implant Mucositis
Monitoring of Implant Diseases: Diagnosis and Monitoring With aMMP-8 Test Technology
68 patients underwent the aMMP-8 chair-side test as well as clinical traditional measurement methods. Those who had one or more implants in their mouth were selected as patients.
- Trial name
- IMP_TRE (NCT06761521)
- Testing
- Peri-Implantitis and Peri-implant mucositis
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hanna Lahteenmaki
Pemphigus, Bullous Pemphigoid
Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population
Pemphigus is a rare autoimmune life-threatening blistering condition affecting skin and mucous membranes. Pemphigus belongs to a family of polygenic disorders.
- Conditions
- Pemphigus, Bullous Pemphigoid, Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses
- Trial name
- NCT05284929
- Testing
- A single blood sample for HLA typing
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sechenov University
Recurrent Aphthous Ulcer, Recurrent Aphthous Stomatitis
Curcumin and Nanocurcumin in Oral Aphthous Ulcer
Recurrent aphthous ulcer is a painful inflammatory lesion with a high prevalence. Since the etiology is not clear, several strategies have been proposed to reduce pain and severity of its symptoms.
- Trial name
- NCT04385979
- Testing
- Gel
- Where
- Iran
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Oral Mucositis
Effect of Black Mulberry Lollipop on Prevention of Oral Mucositis in Children
THE EFFECT OF BLACK MULBERRY LOLLIPOP AND SODIUM BICARBONATE USED IN ORAL CARE ON PREVENTION OF ORAL MUCOSITIS AMONG CHILDREN RECEIVING CHEMOTHERAPY DUE TO CANCER
- Trial name
- NCT04800549
- Testing
- Oral Mucositis
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Sapanca Ilce Devlet Hastanesi
Acquired Immunodeficiency Syndrome, Burning Mouth Syndrome
Thalidomide to Treat Oral Lesions in HIV-Infected Patients
This study will test the effectiveness of topical thalidomide in healing mouth sores in HIV infected patients. Oral (PO) thalidomide heals these sores at a dose of 200 mg per day.
- Conditions
- Acquired Immunodeficiency Syndrome, Burning Mouth Syndrome, HIV Infection
- Trial name
- NCT00001524
- Testing
- Thalidomide
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy
Prevention of Oral Mucositis After Using Chamomile Oral Cryotherapy Versus Oral Cryotherapy in Pediatric Cancer Patients Receiving Chemotherapy.
oral mucositis is a painful situation that significantly affects patients' quality of life with the severe cases being associated with ulcerated mucosa and secondary infection which may lead to life-threatening sepsis.Chamomile…
- Trial name
- NCT03605186
- Testing
- Chamomile oral cryotherapy, Oral cryotherapy
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mucositis
Therapies for Salivary Flux Stimulation in Patients Transplanted With Hematopoietic Stem Cells
The transplantation of hematopoietic stem cells (THSC) is a therapeutic modality developed for the treatment of various diseases such as leukemia, bone marrow aplasia, lymphomas, multiple myeloma, among others.
- Trial name
- NCT00929825
- Testing
- mechanical stimulation (Elastomers), TENS
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Peri-implant Mucositis, Oral Bacterial Infection
Bacterial Microbiota Characterization on Implant-supported PEEK and Titanium Provisional Abutments
The aim of this study is to determine the relative abundances of the different bacterial phyla and families in the microbiota present on the surface of PEEK implant-supported provisional abutments compared to titanium…
- Conditions
- Peri-implant Mucositis, Oral Bacterial Infection, Bacterial Resistance
- Trial name
- NCT03998865
- Testing
- Provisional abutment material
- Where
- Chile
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Michael Wendler Ernst
Apthous Ulcer
Recurrent Aphthous Stomatitis Management in Children Using Diode Laser 980 Nanometer Versus Hyaluronic Acid Gel (RCT)
Thirty children with recurrent apthous ulcer will be divided into 3 groups of different treatment modalities to assess their effect on pain, ulcer size, healing and postoperative pain
- Trial name
- RCT (NCT07922681)
- Testing
- laser therapy, Hyaluronic acid group, Negative control group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Aphthous Stomatitis
Efficacy and Safety of BNP105 in the Treatment of Recurrent Aphthous Stomatitis
The purpose of this study is to evaluate the efficacy and safety of BNP105 in the treatment of recurrent aphthous stomatitis.
- Trial name
- NCT05772338
- Testing
- BNP105 (25 + 25 + 15)
- Where
- 2 sites in Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- EMS
Health Care Associated Infection
Clinical Trial Evaluating Chlorine e6 Derivative-mediated Antimicrobial Photodynamic Therapy as a Treatment for Denture Stomatitis
Objective: This randomized clinical trial assessed antimicrobial Photodynamic Therapy (aPDT) mediated by Photodithazine (PDZ) to treat patients with denture stomatitis (DS).
- Trial name
- NCT04532060
- Testing
- Nystatin, Antimicrobial Photodynamic Therapy
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Oral Mucositis, ORAS
Combination of Diclofenac Potassium and Propolis in the Therapy of Oral Aphthosis
The combination of diclofenac and propolis could enhance the healing of recurrent aphthous ulcers, instantly relieve symptoms, improve the quality of life, and present a de novo and cost-effective regime help in oral ulcer…
- Conditions
- Oral Mucositis, ORAS, Oral Infection, Oral Ulcer
- Trial name
- NCT05413096
- Testing
- Combination of diclofenac potassium and propolis
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Implantation, Peri-implant Mucositis
Periodontal Effects of Orthodontic Mini-Screws
Orthodontic mini-screws (TADs) are commonly used to provide temporary anchorage and prevent unwanted tooth movement during orthodontic treatment.
- Conditions
- Dental Implantation, Peri-implant Mucositis, Orthodontic Anchorage Procedures, Gingival Inflammation and Bleeding
- Trial name
- NCT07052747
- Testing
- Clinical periodontal assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Dr. Mehmet Selim Yildiz
Dental Implantation, Peri-implant Mucositis
Evaluation of Peri-implant Conditions of Orthodontic Mini Implants
This observational study aims to evaluate the peri-implant conditions of mini implants placed during orthodontic treatment. Orthodontic mini implants are commonly used as temporary anchorage devices to prevent or reduce unwanted…
- Conditions
- Dental Implantation, Peri-implant Mucositis, Gingival Inflammation, Implant Stability
- Trial name
- NCT06491849
- Testing
- Peri-implant Condition Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Mehmet Selim Yildiz