Clinical trials: Organ Transplants
Student, Organ Donation
The Effect of Peer-Guided Education on Organ Donation on Organ Donation Attitude
This research will be conducted to determine the effect of peer-guided organ donation education given to anesthesia students on their attitudes towards organ donation.
- Conditions
- Student, Organ Donation, Attitude
- Trial name
- NCT07663981
- Testing
- Peer-led education on organ donation
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Organ Transplantation, Transplantation Immunology
Immune Monitoring and Assay Development in Organ Transplant Recipients
The purpose of this study to develop a well-characterized library of blood, biopsy tissue, and urine samples from transplant patients. Subjects without transplants will also be enrolled for comparison.
- Trial name
- IMP (NCT01283295)
- Where
- 2 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Emory University
Organ Donation, Next of Kin
Bernese Next of Kin Survey Following Organ Donation Request
6 to 18 months after organ donation request a next of kin survey using a standardized questionnaire was conducted.
- Conditions
- Organ Donation, Next of Kin, Post Traumatic Stress Disorder
- Trial name
- NCT03612024
- Testing
- questionnaire
- Where
- Switzerland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Tissue and Organ Procurement, Adolescent Behavior
Organ Donation Interventions Among High Students
The number of persons actively waiting on the national solid organ waiting list continues to rise while the number donating organs has failed to keep pace.
- Conditions
- Tissue and Organ Procurement, Adolescent Behavior, Communication
- Trial name
- NCT02585921
- Testing
- Video Interventions, Donation Discussion Education
- Where
- United States
- Volunteers
- 872 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Solid Organ Transplantation, Pregnancy
Long-term Follow-up of the Offspring Born to Mothers With a Solid Organ Transplant, Transplantlines Next Generation
Background Pregnancy after all types of solid organ transplantation (SOT) is possible, although these have higher risk of pregnancy complications for mother and child, such as preeclampsia and preterm birth.
- Conditions
- Solid Organ Transplantation, Pregnancy, Long-term Follow-up, Kidney Transplant
- Trial name
- NCT07291258
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Tissue and Organ Donation, Communication
Patient and Physician Intervention to Increase Organ Donation
The number of persons on the national solid organ waiting list continues to increase while the number of donated organs has failed to keep pace. In some portions of northeastern Ohio the donation rate is as low as 32%.
- Trial name
- DECIDE (NCT01697137)
- Testing
- Participant Video and Provider Cueing
- Where
- United States
- Volunteers
- 916 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Organ Donor Registration, Organ Donation Education
Increasing Donor Designation Rates in Teenagers: Effectiveness of a Driver's Education Intervention
Four aims were pursued: (1) Evaluate the effectiveness of video messaging on adolescent donor designations in comparison to a regionally-matched historical comparison group of adolescents; (2) Compare the differential…
- Trial name
- NCT03013816
- Testing
- Organ Donation Education: Testimonial Messaging, Organ Donation Education: Informational Messaging, Organ Donation Education: Blended Messaging
- Where
- United States
- Volunteers
- 611 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Brain Death
Thyroxine Replacement in Organ Donors
To compare oral versus intravenous administration of thyroid hormone: 1) for reversibility of hemodynamic instability in organ donors, and, 2) the pharmacokinetics of oral vs iv thyroid administration
- Trial name
- NCT00238030
- Testing
- L-thryoxine, iv thryoxine
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
CMV Infection, EBV
Partially HLA-matched Third Party Antigen Specific T-cells for Infection Post-stem Cell or Solid Organ Transplantation
To assess the safety and biological efficacy of therapeutically administered most closely HLA-matched third party donor-derived specific cytotoxic T lymphocytes (CTLs) targeting cytomegalovirus (CMV) or Adenovirus (Adv) or…
- Conditions
- CMV Infection, EBV, Adenovirus
- Trial name
- R3ACT (NCT02779439)
- Testing
- Virus specific CTLs
- Where
- Australia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Cytomegalovirus
Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT
This trial studies the side effects and how well allogeneic cytomegalovirus-specific cytotoxic T lymphocytes (donor cytomegalovirus [CMV] specific cytotoxic T-lymphocytes [CTLs]) or allogeneic adenovirus-specific cytotoxic T…
- Conditions
- Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Cytomegalovirus, Donor, Solid Organ Transplantation Recipient
- Trial name
- NCT03665675
- Testing
- Allogeneic Cytomegalovirus-Specific Cytotoxic T lymphocytes, Allogeneic Adenovirus-specific Cytotoxic T Lymphocytes
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sumithira Vasu
Organ Donation, Registration for Deceased Organ Donation
Promoting Organ Donor Registration in Family Physician Offices
This study evaluates the effects of using reception staff to prompt patients by providing a pamphlet and an opportunity to register in the waiting room via a mobile tablet on deceased organ donor registration rates.
- Trial name
- NCT03213171
- Testing
- Reception staff providing handout., Mobile Tablet (e.g. iPad)
- Where
- 2 sites in Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Complications of Organ Transplant Stem Cells Umbilical Cord
Treatment Protocol of Child SAA With the Injection of Mesenchymal Stem Cells（Umbilical Cord Derived）
Mesenchymal Stem Cells (MSC) is a non Hematopoietic Stem Cells (HSC) in adult bone marrow and takes part in the bone marrow microenvironment.
- Trial name
- MSC-SAA (NCT02218437)
- Testing
- MSC+ATG
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Kidney Transplantation, Liver Transplantation
Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant
The purpose of this pilot study is to determine if there is clinical correlation between the CKT and transplant recipients who are known to be on minimal or no immunosuppression (presumed tolerant) and those who are on…
- Trial name
- NCT00585858
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Tissue and Organ Procurement, Health Behavior
Community Trial to Enhance Organ Donation
The purpose of this study is to determine the effect of a 5-minute video intervention regarding organ donation and transplantation on increasing the number of organ donor cards signed in Northeastern Ohio Bureau of Motor Vehicles…
- Trial name
- NCT00870506
- Testing
- video
- Where
- United States
- Volunteers
- 973 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University