Clinical trials: Orthodontic Pain
Malocclusion, Pain
Anxiety, Pain, and Quality of Life in Orthodontic Treatment
This study was evaluated anxiety, pain, and oral health-related quality of life in individuals treated with conventional fixed appliances (Group A) and clear aligners (Group B) for moderate malocclusion during the initial phase…
- Conditions
- Malocclusion, Pain, Anxiety, Quality of Life
- Trial name
- NCT06133296
- Testing
- Conventional fixed treatment, Clear aligner treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Orthodontic Discomfort, Pain, Orofacial
Comparison of Patient-reported Pain After Initial Archwire Placement
Three different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective.
- Trial name
- Archwires (NCT03906422)
- Testing
- 3M Unitek 0.016 orthodontic archwire, Device: 0.016" Ormco 27oC NiTi orthodontic archwire, Device: 0.016" Ormco 35oC NiTi orthodontic archwire
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Class II Malocclusion, Division 1
Pain, Discomfort, and Acceptance During Using Electrical Stimulation to Accelerate Orthodontic Teeth Movement
Forty patients with class II division 1 malocclusion who will require extraction of the upper first premolars as a part of the orthodontic treatment plan will be invited to participate in the study.
- Trial name
- NCT05920525
- Testing
- Electrical stimulation, Traditional retraction of the front upper teeth
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Orthodontic Pain (D013850), Malocclusion
Comparison of Three Orthodontic Separators for Pain, Plaque, and Tooth Separation
Orthodontic separators are small devices placed between teeth before fitting braces to create space for bands. This procedure may cause pain, discomfort, and changes in oral hygiene, which can affect plaque buildup and daily…
- Conditions
- Orthodontic Pain (D013850), Malocclusion, Orthodontic Treatment
- Trial name
- SEP-ORTHO (NCT07532044)
- Testing
- Elastomeric Separator, Kesling Separator, Tie wire separator
- Where
- Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Pain
Methods That Reduce Pain During Debonding Fixed Orthodontic Appliance
The goal of this clinical trial is to evaluate the effectiveness of four different methods (including the control group) in reducing pain during debonding of fixed orthodontic appliances in participants requiring the removal of…
- Trial name
- NCT05904587
- Testing
- SureSmile® VPro™, ortho technology, sports advantage, thermal forming soft EVA 3mm, cotton roll
- Where
- Iraq
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain Management, Root Resorption
Photobiomodulation Effect on Vietnamese Orthodontic Patients
Since most orthodontic cases endure for 2 to 3 years or longer, patients are at a high risk of inflammatory root resorption and prolonged orthodontic pain, which is a common and unwanted side effect of their treatment.
- Conditions
- Pain Management, Root Resorption, Orthodontic, Tooth Movement
- Trial name
- NCT07276984
- Testing
- LED device
- Where
- Vietnam
- Volunteers
- 16 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Orthodontic Pain
A Multiple-Dose Safety Study of Fixed Combination of Acetaminophen/Naproxen Sodium in Adolescents With Orthodontic Pain
The purpose of this study is to evaluate the safety of a fixed combination of acetaminophen/naproxen sodium when administered as multiple doses over a period of up to 10 days in adolescents 12 to below 17 years of age with…
- Trial name
- NCT05845008
- Testing
- Acetaminophen/Naproxen Sodium Fixed Combination
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Class II Malocclusion
Evaluation of the Effect of Electrical Stimulation on the Rate of Orthodontic Tooth Movement and the Dental Arches
Thirty-eight patients requiring extraction of maxillary first premolars and maximum anchorage to retract the upper anterior teeth will participate in the study.
- Trial name
- NCT05350280
- Testing
- electric current, Traditional treatment
- Where
- Syria
- Volunteers
- 38 people
- Sponsor
- Damascus University
Debonding, Orthodontic Brackets
Does the Pain Experienced During Orthodontic Treatment and Bracket Removal Depend on the Architecture of the Bracket?
The present research aimed to thoroughly investigate the impact of bracket architecture on pain perception during active treatment, debonding, and adhesive removal.
- Trial name
- Debonding (NCT06324162)
- Testing
- bracket removal pliers, LODI
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Piotr Fudalej
Levels of Pain
Effect of Low Level Laser Therapy on Pain Induced by Placement of Orthodontic Separators in Pediatric Patients
The primary goal of the study is to determine if there is a difference in pain levels following the use of low level laser therapy versus placebo and control after placement of elastomeric orthodontic separators in pediatric…
- Trial name
- NCT02211547
- Testing
- Epic 10 Diode Laser by Biolase Inc.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Orthodontic Pain
Pain Control During Braces Removal Using Transcutaneous Electrical Nerve Stimulation and High-Frequency Vibration
This study aims to find the best method to reduce pain during braces removal. We are comparing transcutaneous electrical nerve stimulation (TENS), high-frequency vibration, and a control group with no additional intervention.
- Trial name
- NCT07293975
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), High-Frequency Vibration
- Where
- Iraq
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Orthodontic Pain
Pain Reduction After Separators Placement
Rationale of study: Separators placement is the primary step in orthodontic treatment and it is almost always accompanied by pain and discomfort which has a direct impact on the compliance and quality of life of patients.
- Trial name
- NCT05777122
- Testing
- lignocaine gel, sugar free chewing gum
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sadaf Bashir
Pain and Discomfort, Orthodontic Appliance Complication
The Role of Paracetamol-caffeine and Laser Irradiation on Controlling Pain and Discomfort During Orthodontic Treatment
Patients with class I malocclusion who have mild to moderate crowding will be treated in this study. The efficacy of low level laser therapy and Panadol-extra® in relieving pain due to orthodontic treatment will be assessed.
- Trial name
- NCT03400111
- Testing
- low-level laser therapy, Panadol-extra
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Dental Malocclusion
Pain and Activity Levels After Orthodontic Separators
The primary aim of this study is to evaluate the reported pain intensity following placement of Orthodontic separators on healthy volunteers aged 15-49 in relation to their recorded physical activity level.
- Trial name
- NCT05615688
- Testing
- Pain Intensity following Placement of Orthodontic Separators
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Lina Sharab
Orthodontic Pain
Acetaminophen Versus Ibuprofen for the Control of Immediate and Delayed Pain Following Orthodontic Separator Placement
The purpose of this research study is to compare pain control effectiveness of two medicines and a placebo (a dummy pill that does not contain any pain relieving medication) to see which one works better at preventing pain when…
- Trial name
- NCT00484744
- Testing
- Acetaminophen, Ibuprofen
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Orthodontic Pain, Pain
Factors Associated With Pain Level Experience in Orthodontic Treatment
Orthodontic pain has been the primary concern from all patients who requires orthodontic treatment. The design of the study will help us comprehend how patient experienced and managed pain during their orthodontic treatment…
- Conditions
- Orthodontic Pain, Pain, Orthodontic Appliance Complication
- Trial name
- NCT04834466
- Testing
- Pain Level experience during orthodontic treatment
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chia Jung Lee
Orthodontic Treatment
Curve of Spee: Speed of Leveling Using Different Orthodontic Archwires
The objectives if this study was to evaluate the efficacy of 3 different rectangular archwires in the correction of the curve of Spee (COS), to record the time needed to level excessive COS in the mandibular arch using the 3…
- Trial name
- NCT04549948
- Testing
- 0.017X0.025 Stainless steel, 0.019X0.025 Stainless steel, 0.021X0.025 B-Titanium archwire
- Where
- Jordan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pain, Orofacial
Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain Management
The purpose of this study is to compare the effectiveness of a combined ibuprofen and acetaminophen regimen in controlling discomfort for 4 days after initial orthodontic appliance placement as compared to ibuprofen alone or a…
- Trial name
- NCT04059172
- Testing
- Ibuprofen 200 mg and acetaminphen 650 mg, Ibuprofen 200 mg
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Orthodontic Appliance, Pain
The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain
The goal of this clinical trial is to determine whether an intraoral Transcutaneous Electrical Nerve Stimulation (TENS) device can reduce pain during orthodontic alignment and leveling in adolescents and adults.
- Conditions
- Orthodontic Appliance, Pain, Transcutaneous Electric Nerve Stimulation, Orthodontic Appliance Complication
- Trial name
- NCT06573996
- Testing
- Active TENS Device
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of the Pacific
Orthodontic Pain (D013850)
Efficacy of Selective COX-2 Inhibitors in Relieving Orthodontic Pain
The purpose of this study is to compare the efficacy of selective COX-2 inhibitors{ etoricoxib vs celecoxib )in relieving orthodontic pain , after initial bonding and arch wire insertion.
- Trial name
- EOSCOX2 (NCT07559682)
- Testing
- Celecoxib, Etoricoxib (Treatment Group)
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Sharif Medical Research Center