Clinical trials: Orthopaedic Surgery
Surgery, Anxiety
Pediatric Preoperative Virtual Reality Program
Does the introduction of a preparatory virtual reality (VR) program that is used in the home environment, have an effect on the anxiety level of children immediately before surgery, prior to administration of preoperative…
- Trial name
- PPVRP (NCT03957525)
- Testing
- Pre-Operative Preparatory Virtual Reality Program
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- Thoralf Liebs
Idiopathic Toe-walking
Efficacy of Surgery for Idiopathic Toe Walking
BACKGROUND: For children who walk on their tip toes, surgery is often done to lengthen their Achilles Tendon. However, there is little research to help children's surgeons choose which children with idiopathic toe walking should…
- Trial name
- FOREFOOT (NCT06610591)
- Testing
- Achilles Lengthening Surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Musculoskeletal Deformity, Musculoskeletal Diseases
Customized Bone Allografts by 3D-printing
Virtual surgical planning (VSP), the simulation of bone corrections in virtual reality ("Computer Aided Surgical Simulation": CASS) and 3D printing of customized implants and devices are achieving an increasingly central role in…
- Conditions
- Musculoskeletal Deformity, Musculoskeletal Diseases, Musculoskeletal Disorder
- Trial name
- 3D-MALF 2 (NCT05700526)
- Testing
- Planning of multiplanar and/or multifocal osteotomies in children by using VSP, PSIs and customized structural bone allograft, Routine preparation of bone graft according to standard protocols, Preparation of bone graft with virtual bone-matching and GSIs
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Istituto Ortopedico Rizzoli
Orthopedic Disorder
Routine Preoperative Evaluation in Surgical Patient
The "routine" pre-operative tests in healthy orthopaedic patients undergoing intermediate/ major surgery are not justified. In this study of 670 healthy orthopedic patients with 7610 preoperative tests, investigators found that…
- Trial name
- NCT04196166
- Testing
- preoperative blood tests
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Primary Spondylodiscitis, Pyogenic Spondylodiscitis
One Year Results of Managing Primary Spondylodiscitis
Primary spondylodiscitis is a severe infectious condition involving the spinal discs and adjacent vertebrae. It often causes significant back pain and requires careful management, typically involving long-term antibiotics and…
- Conditions
- Primary Spondylodiscitis, Pyogenic Spondylodiscitis, Spinal Infection
- Trial name
- NCT07509983
- Volunteers
- 50 people
- Sponsor
- Assiut University
Tourniquet Complications, Paresis
Tourniquet Complications in Orthopaedic Surgery
The purpose of the study is to establish the number and nature of complications that we, the researchers, have with the use of a tourniquet in orthopaedic surgery in Norway.
- Conditions
- Tourniquet Complications, Paresis, Palsy, Nerve Compression
- Trial name
- NCT00212394
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Norwegian University of Science and Technology
Radiation Exposure
Reference Dose Levels During Fluoroscopically Guided Procedures in Operating Rooms
This study is conducted by a working group of the French Society of Medical Physics (SFPM). Its main aim is to establish reference dose levels for the most common procedures performed in operating rooms using mobile X-ray…
- Trial name
- NCT03649451
- Where
- France
- Volunteers
- 8,840 people
- Sponsor
- Societe Francaise de Physique Medicale
Gastric Insufflation, I-gel
Gastric Insufflation Volume Using I-gel Versus Ambu AuraGain in Pediatric Patients Undergoing Elective Orthopedic Operations Under General Anesthesia
Our study aimed to compare the gastric insufflation volume between Ambu AuraGain and i-gel and its relationship with the oropharyngeal sealing pressure and the incidence of postoperative complications in generally anesthetized…
- Conditions
- Gastric Insufflation, I-gel, Ambu AuraGain, Pediatric
- Trial name
- NCT06853756
- Testing
- Ambu Auragain, I-gel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Developmental Dysplasia of the Hip (DDH)
Early Outcomes of Arthroscopic Versus Open Reduction for Developmental Dysplasia of the Hip in Children
This study was designed to determine whether arthroscopic-assisted reduction offers better early surgical outcomes than open reduction for treating developmental dysplasia of the hip in children.
- Trial name
- NCT06747767
- Testing
- Arthroscopy, Open reduction
- Where
- Iraq
- Volunteers
- 43 people
- Sponsor
- Hawler Medical University
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Pediatric Patients, Orthopedic Surgery
Nociception Level Index as a Verbal Tool of Pain in Children
60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management…
- Conditions
- Pediatric Patients, Orthopedic Surgery, Extremity Fractures Lower, Extremity Fractures Upper
- Trial name
- NCT05716243
- Testing
- The nociception level index monitorization, The nociception level index measurement;postoperative
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Polydactyly Toe, Thumb Hypoplasia
Clonidine for Tourniquet-related Pain in Children
This study is designed as a randomized, placebo-controlled, double-blinded, clinical trial with two parallel groups. This study investigates the association between a single dose of the drug, Clonidine, and the total amount of…
- Conditions
- Polydactyly Toe, Thumb Hypoplasia, Trigger Finger, Polydactyly; Fingers
- Trial name
- CLOTCH (NCT04564430)
- Testing
- Catapresan, Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Rupture of Anterior Cruciate Ligament, Osteoarthritis
Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): Onsite Follow-up
In this study we will examine patients who have undergone unilateral ACL reconstruction surgery to determine which structural and functional characteristics of the knee two and ten years post reconstruction surgery, aspects of…
- Trial name
- MOON-Onsite (NCT00478894)
- Where
- 4 sites in United States
- Volunteers
- 432 people
- Sponsor
- Vanderbilt University
Puncture, Surgical Gloves
The Effect of Using Double Gloves on Perforation in Orthopedic Surgery
Aim: This study aimed to investigate the effect of using double gloves on perforation in orthopedic surgery. Materials and Method: The randomized controlled experimental study was conducted between 30.11.2021 and 31.03.2022 in…
- Conditions
- Puncture, Surgical Gloves, Orthopedic Disorder
- Trial name
- NCT05928663
- Testing
- double surgical gloves, single surgical gloves
- Where
- Turkey (Türkiye)
- Volunteers
- 1,170 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Unilateral Cleft Lip, Nasoalveolar Molding
Nasolabial Soft Tissue Esthetics and Maxillary Changes in Unilateral Cleft Lip and Palate Using PreSurgical Infant Orthopedics With Different Approaches
The nasal deformity is an abnormality in the appearance and structure of the nose in cleft patients having unilateral cleft lip and palate (UCLP).
- Trial name
- PSIO (NCT05940389)
- Testing
- Naso Alveolar Mold, Taping with nasal elevator:
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Orthopedic Disorder
End Button Tenodesis in Failed Developmental Dysplasia of the Hip Surgery
Adequate growth and development of the hip depends on two main factors: concentric positioning of femoral head into the acetabular cavity and adequate balance in growth between tri-radiate and acetabular cartilage.
- Trial name
- NCT05603858
- Testing
- Tenodesis by end button
- Volunteers
- 3 people
- Sponsor
- Al-Azhar University
Post Operative Pain, Acute
A Study of Combogesic® 325 in Adolescent Patients With Moderate to Severe Postoperative Pain Associated With Orthopedic Surgery
Combogesic® 325 contains a combination of ibuprofen and acetaminophen. The purpose of this study is to compare the pain relief effects of Combogesic® 325mg and acetaminophen and to evaluate the safety of Combogesic® 325mg in…
- Trial name
- NCT07225140
- Testing
- Combogesic® tablets, Acetaminophen 500mg
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- AFT Pharmaceuticals, Ltd.
Acute Postoperative Pain, Motor Activity
Axillary Brachial Plexus Block Using 0.25% Bupivacaine Versus Using 0.19%Bupivacaine in Pediatrics
Postoperative pain is a common manifestation in orthopedic patients, mainly due to intraoperative tissue damage and inadequate intraoperative pain assessment and management .Axillary brachial plexus block provides motor and…
- Trial name
- NCT05386095
- Testing
- 0.25%Bupivacaine Axillary brachial plexus block, 0.19% Bupivacaine Axillary brachial plexus block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Orthopedic Disorder, Thoracic
Epidemiological Data on Pain
The ALGOBASES project is an observational epidemiological study of pain through the collection of pain evaluation questionnaires and information with the aim of creating a descriptive "pain" evaluation in all patients who need to…
- Conditions
- Orthopedic Disorder, Thoracic, Gynecological; Surgery (Previous), Causing Obstructed Labor, Affecting Fetus, Pain
- Trial name
- ALGOBASES (NCT04546594)
- Sponsor
- University Hospital, Lille
Sports Medicine Injuries
Effect of Personalized Pain Coaches After Orthopaedic Surgery for Patients With Sports Medicine Injuries
Patients experiencing sports medicine-related injuries are particularly vulnerable to developing both chronic pain and experiencing prolonged opioid use.
- Trial name
- NCT05821699
- Testing
- LCS (Life Care Specialist), Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- Emory University