Clinical trials: Orthopaedic Surgery
Anesthesia, Local, Anesthesia
Regional Anesthesia in Pediatric Orthopaedic Patients
To identify the benefits from regional anesthesia use as pain management in the pediatric population by delineating the differences in efficacy of continuous nerve blockade versus single-shot techniques after pediatric…
- Conditions
- Anesthesia, Local, Anesthesia, Orthopedic Disorder
- Trial name
- NCT04669145
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ochsner Health System
Anesthesiology, Pediatrics
A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor
Study hypothesis: The Cardiotronic ICON non-invasive cardiac output monitor gives accurate information when placed on a patient's Right or Left side.
- Conditions
- Anesthesiology, Pediatrics, General Surgery, Orthopedics
- Trial name
- NCT01678066
- Testing
- Bilateral cardiac output
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Congenital Bleeding Disorder, Haemophilia A With Inhibitors
A Long-term Assessment of Physical Activity, Range of Motion, and Functional Status Following Elective Orthopedic Surgery in Hemophilia Patients With Inhibitors
This study is conducted in the United States of America (USA). The aim of this study is to assess the long-term (5+ years) postoperative functional outcomes of elective orthopaedic surgery (EOS) patients from previously reported…
- Conditions
- Congenital Bleeding Disorder, Haemophilia A With Inhibitors, Haemophilia B With Inhibitors
- Trial name
- NCT01830712
- Testing
- eptacog alfa (activated)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Novo Nordisk A/S
Coronavirus Infection, Orthopedic Disorder
Retrospective Case Series of COVID19+ Patients Undergoing Orthopedic Surgery
Over the last months, the Rizzoli Orthopedic Institute in Bologna, Italy, has drained orthopedic urgencies from all other hospitals in the urban and suburban area.
- Conditions
- Coronavirus Infection, Orthopedic Disorder, Bone Fracture, Bone Metastases
- Trial name
- COVID19&SURG (NCT05881343)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Ortopedico Rizzoli
Puncture, Surgical Gloves
The Effect of Using Double Gloves on Perforation in Orthopedic Surgery
Aim: This study aimed to investigate the effect of using double gloves on perforation in orthopedic surgery. Materials and Method: The randomized controlled experimental study was conducted between 30.11.2021 and 31.03.2022 in…
- Conditions
- Puncture, Surgical Gloves, Orthopedic Disorder
- Trial name
- NCT05928663
- Testing
- double surgical gloves, single surgical gloves
- Where
- Turkey (Türkiye)
- Volunteers
- 1,170 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Rheumatoid Arthritis, Orthopedic Surgery
Local Analgesia in Knee- and Hipatroplastic Surgery in Patients With Rheumatic Disease: Extra- vs. Intracapsulare Position of Catheter
Postoperative pain is part of surgery trauma. In orthopedic surgery artroplastic replacement of knee- and hipjoints are common. Postoperative pain relieve can be complicated.
- Conditions
- Rheumatoid Arthritis, Orthopedic Surgery, Analgesia
- Trial name
- NCT01050738
- Testing
- Position of catheter
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Spenshult Hospital
Orthopedic Disorder, Thoracic
Epidemiological Data on Pain
The ALGOBASES project is an observational epidemiological study of pain through the collection of pain evaluation questionnaires and information with the aim of creating a descriptive "pain" evaluation in all patients who need to…
- Conditions
- Orthopedic Disorder, Thoracic, Gynecological; Surgery (Previous), Causing Obstructed Labor, Affecting Fetus, Pain
- Trial name
- ALGOBASES (NCT04546594)
- Sponsor
- University Hospital, Lille
Axillary Brachial Plexus Block
The Efficacy of Intravenous Dexamethasone on the Duration of Analgesia of Ultrasound Guided Axillary Brachial Plexus Block in Pediatric Patients Undergoing Below Elbow Orthopaedic Surgeries
Postoperative pain is a common manifestation in orthopedic patients, mainly due to intraoperative tissue damage , inadequate intraoperative pain assessment and management.
- Trial name
- NCT05466500
- Testing
- Ultrasound guided axillary block with intravenous dexamethasone, Ultrasound guided axillary block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Sports Medicine Injuries
Effect of Personalized Pain Coaches After Orthopaedic Surgery for Patients With Sports Medicine Injuries
Patients experiencing sports medicine-related injuries are particularly vulnerable to developing both chronic pain and experiencing prolonged opioid use.
- Trial name
- NCT05821699
- Testing
- LCS (Life Care Specialist), Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- Emory University
Cerebral Palsy, Hip Surgery Corrective
Tranexamic Acid to Reduce Blood Loss After Varus Derotation Osteotomy
TABLO (Tranexamic Acid to reduce Blood Loss after varus derotation Osteotomy) is a clinical trial of postoperative tranexamic acid vs placebo in non-ambulatory children with cerebral palsy (CP) undergoing reconstructive hip…
- Conditions
- Cerebral Palsy, Hip Surgery Corrective, Tranexamic Acid Use, Blood Loss, Surgical
- Trial name
- TABLO (NCT07672158)
- Testing
- Tranexamic Acid (IV)
- Where
- Australia
- Volunteers
- 52 people
- Sponsor
- Murdoch Childrens Research Institute
Rupture of Anterior Cruciate Ligament
Multicenter Orthopaedics Outcomes Network for ACL Reconstructions
The purpose of this study is to determine the effect of modifiable risk factors on knee function, osteoarthritis, and re-rupture of the anterior cruciate ligament (ACL) following ACL reconstruction.
- Trial name
- NCT00463099
- Where
- 8 sites in United States
- Volunteers
- 3,294 people
- Sponsor
- Vanderbilt University Medical Center
Orthopaedic Surgery
The Effect of Digital Team-based Communication on Patient-initiated Telephone Contacts to Hospital After Discharge
The aim of this study is to investigate the effects of eDialogue versus standard communication pathways on patient-initiated telephone contacts to the hospital following discharge.
- Trial name
- NCT05601765
- Testing
- Standard communication pathways after discharge, Digital team-based communication after discharge
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aalborg University Hospital
Surgery, Orthopedic Disorder
Perioperative Factors Impacting Surgical Risk and Outcomes in Children
This prospective study will measure various factors in children coming in for ambulatory surgery and attempt to create a scoring system that would be able to predict post-operative outcomes.
- Trial name
- NCT03436667
- Testing
- Spirometry, Reaction Time
- Where
- United States
- Sponsor
- Nationwide Children's Hospital
Cerebral Palsy, Hemiplegia
Functional Benefits of Multisite Upper Limb Surgery in Children With Unilateral Cerebral Palsy (RETRO-CHIRc)
This retrospective study evaluates the functional impact of individualized multisite neuro-orthopedic upper limb surgery in children with unilateral cerebral palsy (hemiplegic CP).
- Trial name
- RETRO-CHIRc (NCT07891078)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
The Precision Personal Timeline in Definitive Surgery Associated With Outcome
Timing of Damage Control Orthopedic Surgery
The decision to operate and surgical timing on multi-trauma patients remains controversial, inappropriate surgical timing may cause more complications which lead to poor prognosis.
- Trial name
- NCT05785143
- Testing
- Utilizing dry lab database to analyze the prognostic factors of multi-trauma patients and determine the optimal timing of definitive orthopedic operation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- China Medical University Hospital
Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) Gold Standard for Blood Loss
The purpose of this study is to establish a benchmark for measuring blood loss by directly measuring the change in red cell volume before and after surgery and to compare established blood loss estimators to this benchmark in…
- Trial name
- NCT03990376
- Testing
- Radioisotope I-131-labeled albumin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Other Conditions That May Be A Focus of Clinical Attention
Effectiveness of Buddhist Intergrated Group Intervention on Minefulness in Adolescents
The pupose of the study is to determine the effectiveness of the Buddhist integrated group intervention improve the mindfulness in adolescents by a randomized controlled trial.The study divede the adolescents in two groups group…
- Trial name
- NCT01605604
- Testing
- buddhist mind fullness
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Scoliosis
Pharmacokinetics of Aminocaproic Acid in Scoliosis Surgery
This study will evaluate the pharmacokinetics of antifibrinolytic drug epsilon-aminocaproic acid (EACA) in children undergoing Posterior spinal fusion surgery (PSF) at The Children's Hospital of Philadelphia (CHOP) who receive…
- Trial name
- NCT01408823
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Philadelphia
Orthopedic Procedures, Methicillin-resistant Staphylococcus Aureus
Treatment of Patients Colonized With Methicillin-Resistant Staphylococcus Aureus Prior to Bone and Joint Surgery
The investigators anticipate that utilization of retapamulin preoperatively will eliminate MRSA colonization among patients who are colonized in their nares.
- Trial name
- TOPS-MRSA (NCT00903279)
- Testing
- Altabax (retapamulin)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bay Pines VA Healthcare System
Quality of Life, Anxiety
A Telemedicine Solution for Remote Support of Rehabilitation, for Patients Undergoing, Total Hip Arthroplasty Surgery
The RRS project is a Randomized Clinical Trial documenting the effect of Remote Rehabilitation and Support via a telemedicine solution for patients undergoing an optimized fast-track orthopedic surgery procedure with the…
- Trial name
- RRS (NCT00969020)
- Testing
- remote rehabilitation support
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Regionshospitalet Silkeborg