Clinical trials: Orthopedic Operations
Idiopathic Toe-walking
Efficacy of Surgery for Idiopathic Toe Walking
BACKGROUND: For children who walk on their tip toes, surgery is often done to lengthen their Achilles Tendon. However, there is little research to help children's surgeons choose which children with idiopathic toe walking should…
- Trial name
- FOREFOOT (NCT06610591)
- Testing
- Achilles Lengthening Surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Severe Hyperglycemia, Postoperative Infection
Intraoperative Hyperglycemia and Infections After Orthopedic Surgery
Postoperative infections are a common complication. A relationship between perioperative severe hyperglycemia and postoperative infections has been found in patients undergoing craniotomy.
- Conditions
- Severe Hyperglycemia, Postoperative Infection, Orthopedic Patients
- Trial name
- NCT03903354
- Testing
- Incidence of infections within 7 days postoperatively
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Federico Bilotta
Laryngeal Masks, Pharyngitis
Postoperative Sore Throat in Children: Comparison Between Two Supraglottic Devices, Ambu® AuraOnce™ Laryngeal Mask Airway (LMA) and I-Gel®.
Sore throat is minor but well recognized complaint after receiving general anaesthesia. It is rated as 8th most undesirable outcome in postoperative period.It not only affects the patient's satisfaction but also can affect…
- Conditions
- Laryngeal Masks, Pharyngitis, Minors, Anesthesia
- Trial name
- NCT03140228
- Testing
- I-Gel, LMA
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Sports Medicine Injuries
Effect of Personalized Pain Coaches After Orthopaedic Surgery for Patients With Sports Medicine Injuries
Patients experiencing sports medicine-related injuries are particularly vulnerable to developing both chronic pain and experiencing prolonged opioid use.
- Trial name
- NCT05821699
- Testing
- LCS (Life Care Specialist), Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- Emory University
Femoroacetabular Impingement Syndrome
Early Versus Delayed Weightbearing in Femoroacetabular Impingement Syndrome Patients
Femoroacetabular impingement syndrome (FAIS) is a condition caused by an abnormal bone structure that causes the bones on either side of the hip joint to impinge on each other during certain movements, thus causing pain.
- Trial name
- FASTHIP (NCT05256628)
- Testing
- Early Weightbearing, Protected Weightbearing
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Women's College Hospital
Tendon Disorder
A Musculoskeletal Ultrasound Course for Orthopedic Surgery Residents
A group of orthopedic surgery residents underwent a structured online and practical musculoskeletal ultrasound course. Their proficiency on a written and practical exam, as well as frequency and comfort when using was recorded…
- Trial name
- NCT04204369
- Testing
- Ultrasound education curriculum
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Anterior Cruciate Ligament Repair
Minimizing Tourniquet Pressures in Paediatric Orthopaedic Knee Surgery
Tourniquet cuffs are routinely used to stop blood flow in patients' arms or legs during surgery. This allows surgeons to better visualize anatomical structures during the procedure.
- Trial name
- NCT00439153
- Testing
- Tourniquet instrument capable of measuring LOP in combination with tourniquet cuffs
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- University of British Columbia
Scoliosis, Regional Anesthesia
Erector Spine Plane (ESP) Block for Analgesia in Pediatric Scoliosis Surgery
Postoperative pain after scoliosis correction surgery is severe and usually requires long-term intravenous opioid therapy. Local anesthetic options are limited and include intrathecal opioids and epidural analgesia.
- Conditions
- Scoliosis, Regional Anesthesia, Pediatric Anesthesia, Orthopedic Disorder of Spine
- Trial name
- NCT05944393
- Testing
- Ropivacaine 0.2% Injectable Solution, Normal saline 0.9% Injectable Solution
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Poznan University of Medical Sciences
Scoliosis
The Idiopathic Scoliosis and Its Treatment (Orthopaedic and Surgery): Effect of the Severity, the Orthosis and the Arthrodesis on the Gait
The purposes of this study were as follows: 1) to compare locomotion parameters (kinematic, EMG, mechanical work and energy cost changes during walking in able-bodied subjects and AIS patients,2) to evaluate the effects of the…
- Trial name
- scoliosis (NCT00842218)
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) Gold Standard for Blood Loss
The purpose of this study is to establish a benchmark for measuring blood loss by directly measuring the change in red cell volume before and after surgery and to compare established blood loss estimators to this benchmark in…
- Trial name
- NCT03990376
- Testing
- Radioisotope I-131-labeled albumin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Congenital Skelectal Anomaly
A Comparative Study of the Effect of Epidural Dexmedetomidine Versus Fentanyl Added to Ropivacaine in Pediatric Orthopedic Surgery
The purpose of this study is to evaluate the effect of epidural dexmedetomidine added to ropivacaine in pediatric orthopedic surgery
- Trial name
- NCT02375191
- Testing
- fentanyl, dexmedetomidine, Ropivacaine
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Congenital Bleeding Disorder, Haemophilia A With Inhibitors
A Long-term Assessment of Physical Activity, Range of Motion, and Functional Status Following Elective Orthopedic Surgery in Hemophilia Patients With Inhibitors
This study is conducted in the United States of America (USA). The aim of this study is to assess the long-term (5+ years) postoperative functional outcomes of elective orthopaedic surgery (EOS) patients from previously reported…
- Conditions
- Congenital Bleeding Disorder, Haemophilia A With Inhibitors, Haemophilia B With Inhibitors
- Trial name
- NCT01830712
- Testing
- eptacog alfa (activated)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Novo Nordisk A/S
Pain
Preemptive Genotyping and Pain Management
The purpose of this study is to see if testing for genes related to pain and pain management before surgery affects how patients are treated for pain after surgery.
- Trial name
- NCT01813695
- Testing
- Preemptive genotyping in medical record, Genotyping not included in electronic medical record
- Where
- United States
- Volunteers
- 576 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Degenerative and Traumatic Pathology of the Knee, Degenerative and Traumatic Pathology of the Shoulder and Elbow
Web Based Orthopaedic Sports Medicine Registry
The purpose of this study is to establish an international, web based clinical registry to collect baseline characteristics of patients undergoing orthopaedic, sports medicine, arthroscopy, and related surgery, and the subsequent…
- Conditions
- Degenerative and Traumatic Pathology of the Knee, Degenerative and Traumatic Pathology of the Shoulder and Elbow, Degenerative and Traumatic Pathology of the Foot and Ankle, Degenerative and Traumatic Pathology of the Hand and Wrist
- Trial name
- NCT01191151
- Where
- 258 sites in United States, Canada and 3 more
- Volunteers
- 12,500 people
- Sponsor
- Arthrex, Inc.
Orthopedic Disorder
Parental Perceptions on Prescription Opioid Use
This study involves an anonymous survey given to parents regarding their perceptions on prescription opioid use for pain control in children undergoing orthopedic surgery.
- Trial name
- NCT05344118
- Testing
- Survey
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Nationwide Children's Hospital
Pediatric Patients, Orthopedic Surgery
Nociception Level Index as a Verbal Tool of Pain in Children
60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management…
- Conditions
- Pediatric Patients, Orthopedic Surgery, Extremity Fractures Lower, Extremity Fractures Upper
- Trial name
- NCT05716243
- Testing
- The nociception level index monitorization, The nociception level index measurement;postoperative
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Patient Blood Management
Impact of Patient Blood Management (PBM) at the Schulthess Clinic
Aim of this study is to analyze the transfusion requirements of allogenic blood products at the Schulthess Clinic for patients that had major orthopedic or major spine surgery between 2019 and 2024 order to identify patients at…
- Trial name
- PBM (NCT06363214)
- Testing
- Patient blood management
- Volunteers
- 16,000 people
- Sponsor
- Schulthess Klinik
Orthopaedic Surgery (30 Minutes or Longer)
The Effect of Plasma-air-filtration on the Incidence of Surgical Site Infections in Orthopaedic Surgery
The study is a multicenter, double-blind, randomized, controlled trial conducted at six major university and teaching hospitals with a catchment population of approximately 2 million.
- Trial name
- EPOS (NCT02695368)
- Testing
- Novaerus NV800 on, Novaerus NV800 off, Novaerus NV800 on or off
- Where
- Sweden
- Volunteers
- 45,000 people
- Sponsor
- Karolinska Institutet
Hip Arthroplasty
Stem Cells Predicting Orthopedic Outcomes
This is a pilot study to provide preliminary data of the association between bone mineral denity adjacent to acetabular implants, as measured by quanitative computed tomography (QCT), at least 2 years post Total Hip Arthoplasty…
- Trial name
- NCT01366911
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Orthopedic Disorder
Routine Preoperative Evaluation in Surgical Patient
The "routine" pre-operative tests in healthy orthopaedic patients undergoing intermediate/ major surgery are not justified. In this study of 670 healthy orthopedic patients with 7610 preoperative tests, investigators found that…
- Trial name
- NCT04196166
- Testing
- preoperative blood tests
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University