Clinical trials: Osteoprotegerin
Acute Charcot Neuroarthropathy
Clinico-Radiological Characterisation for Remission of Acute Charcot-Neuroarthropathy of Foot.
Charcot's neuro-arthropathy is a condition which is generally prevalent among the diabetic patients. Acute charcot's neuro-arthropathy is characterized by signs of inflammation, hot, red swelling around the involved joint along…
- Trial name
- NCT06017011
- Testing
- Total contact cast
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Malocclusion
Relationship Between Malocclusion Severity and Periodontitis Risk
The goal of this observational study is to examine the potential relationship between the severity of orthodontic malocclusion and the risk of developing periodontitis in individuals by evaluating salivary and gingival crevicular…
- Trial name
- NCT07127744
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Pain Perception, Root Resorption
The Potential Effect of the Local Administration of Vitamins C and E on Orthodontic Treatment: A Randomized Clinical Trial
Brief Summary of the Study This study investigates the effects of locally administered vitamins C and E on orthodontic tooth movement during the initial stage of treatment.
- Conditions
- Pain Perception, Root Resorption, Rate of Orthodontic Tooth Movement, Biomarkers
- Trial name
- NCT06847880
- Testing
- 1: Vitamin C Supplementation, Vitamin E Supplementation, Saline Solution (Control)
- Where
- 3 sites in Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
RETT Syndrome With Proven MECP2 Mutation
Osteoporosis in RETT Syndrome
Based on our clinical observations, many girls with RETT syndrome, a severe neuro-developmental encephalopathy, suffer from osteoporosis which can appear at a very early age (before age 10) and can lead to fractures, pain and a…
- Trial name
- OSRETT (NCT02110797)
- Testing
- biological markers and evaluation of the mineral density at the lumber spine using DEXA
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 2 Diabetes
Simvastatin Reduces Circulating Osteoprotegerin Levels in Patients With Type 2 Diabetes
Diabetes is associated with dyslipidaemia leading to generalized atherosclerosis, cardiovascular disease (CVD) and nephropathy. Osteoprotegerin (OPG), a glycoprotein involved in bone homeostasis, has been implicated in the…
- Trial name
- NCT00471549
- Testing
- Statin (simvastatin)
- Volunteers
- 18 people
- Sponsor
- University of Aarhus