Clinical trials: Other Neurological Disorders
Schizophrenia, Tardive Dyskinesia, Metabolic Syndrome
The Monitor of Serum Prolactin Level in a 3 Months Aripiprazole Trial
A short term post-market monitoring of serum prolactin level change among patients with schizophrenia shifting from other antispychotics to different dosages of aripiprazole.
- Trial name
- NCT00468533
- Testing
- Aripiprazole
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Yu-Li Hospital
Psychosis, Schizophrenia
Goals in Focus: CBT for Motivational Negative Symptoms of Psychosis
This pilot feasibility trial aims to evaluate the "Goals in Focus" intervention for motivational negative symptoms in people with psychosis.
- Conditions
- Psychosis, Schizophrenia, Negative Symptoms With Primary Psychotic Disorder
- Trial name
- GIF (NCT05252039)
- Testing
- Goals in Focus
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Hamburg-Eppendorf
Amyotrophic Lateral Sclerosis Type 4, Inherited Neurological Disorders of RNA Processing
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing
Background: Amyotrophic lateral sclerosis type 4 (ALS4) is an inherited motor neuron disease. People with ALS4 have a change in the amount of RNA and DNA that bind together.
- Trial name
- NCT04394871
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Temporomandibular Disorder, Orofacial Pain
An Open Label Study Assessing REN Treatment in Headache Management in Temporomandibular Disorders
Temporomandibular disorders (TMD) encompass a group of conditions involving the masticatory muscles, temporomandibular joint (TMJ), and associated structures.
- Trial name
- NCT07639944
- Testing
- Nerivio treatment
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Theranica
Neuroectodermal Tumors, Primitive, Liver Neoplasms
NAC to Prevent Cisplatin-induced Hearing Loss
Cisplatin is a key chemotherapy agent for the treatment of multiple childhood cancers but causes permanent hearing loss. This study investigates the drug N-acetylcysteine (NAC) to determine the dose necessary to protect hearing…
- Conditions
- Neuroectodermal Tumors, Primitive, Liver Neoplasms, Osteosarcoma, Other Childhood Cancers Using Cisplatin-based Regimens
- Trial name
- NCT02094625
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Children's Hospital Los Angeles
Cancer, Cardiovascular Disease
NCGENES: North Carolina Clinical Genomic Evaluation by NextGen Exome Sequencing
This study is part of a larger consortium project investigating the validity and best use of next-generation sequencing (in particular, whole exome sequencing, or WES) in clinical care.
- Conditions
- Cancer, Cardiovascular Disease, Neurologic Dysfunction, Congenital Abnormalities
- Trial name
- NCGENES (NCT01969370)
- Testing
- Experimental
- Where
- United States
- Volunteers
- 645 people
- Sponsor
- University of North Carolina, Chapel Hill
Mucopolysaccharidosis II
Iduronate-2-sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II)
The purpose of this study is to determine whether the administration of iduronate-2-sulfatase enzyme in a weekly or every other week therapy frequency is safe and efficacious in patients with MPS II.
- Trial name
- NCT00069641
- Testing
- Iduronate-2-sulfatase enzyme replacement therapy
- Where
- 9 sites in United States, Brazil and 2 more
- Volunteers
- 96 people
- Sponsor
- Shire
Autoimmune Encephalitis
GWAS in NMDAR Encephalitis
Autoimmune encephalitis are characterized by the subacute development of memory deficits, altered mental status, and psychiatric symptoms, generally in association with anti-neuronal antibodies.
- Trial name
- NCT05225883
- Testing
- GWAS
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Hospices Civils de Lyon
Attention Deficit Disorder With Hyperactivity, Bipolar Disorder
Genetic Aspects of Neurologic and Psychiatric Disorders
The purpose of this study is to improve the understanding of the genetic causes of specific neurologic and psychiatric disorders.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Bipolar Disorder, Mental Disorder Diagnosed in Childhood, Mental Retardation
- Trial name
- NCT00001544
- Where
- United States
- Volunteers
- 1,227 people
- Sponsor
- National Institute of Mental Health (NIMH)
Schizophrenia
A Neurobiological Study on Heterogeneity of Schizophrenia: Genetic Variations and Neurobiological Differentiations
Schizophrenia (SCH) is a devastating brain disorder with grave personal, family and social cost. SCH is a complex and heterogeneous (both genetic and clinical) disorder with oligogenetic endowed vulnerability risk of disease…
- Trial name
- SONPOS (NCT01075373)
- Where
- Taiwan
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Infantile Colic, Infantile Functional Gastrointestinal Disorders
A Phase I Study to Evaluate the Oral Absorption of Nepadutant in Infants
The purpose of the study is to evaluate the gastrointestinal absorption of nepadutant after single dose as oral solution (and the effect of age on its oral absorption) in infants.
- Trial name
- NCT00655083
- Testing
- Nepadutant
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Menarini Group
Anxiety Disorder, Head Injury
Neuropsychological Evaluation of Psychiatric and Neurological Patients
This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning…
- Conditions
- Anxiety Disorder, Head Injury, Mood Disorder, Schizophrenia
- Trial name
- NCT00001192
- Where
- 7 sites in United States, France and 1 more
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Alzheimer's Disease, Psychosis
Treatment of Psychosis and Agitation in Alzheimer's Disease
Clinically, many patients with AD show no response or minimal response to antipsychotics for symptoms of agitation/aggression or psychosis, or they have intolerable side effects on these medications.
- Conditions
- Alzheimer's Disease, Psychosis, Agitation
- Trial name
- NCT02129348
- Testing
- Lithium
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- New York State Psychiatric Institute