Clinical trials: Outcome Assessment
Burns, Liver Fibroses
Liver, Pancreas and Thyroid Function in Burn Patients
The purpose of this study is to determine the extent to which severe burn injuries affect the morphology and function of liver, pancreas and thyroid.
- Conditions
- Burns, Liver Fibroses, Pancreas Disease, Thyroid Diseases
- Trial name
- NCT03598283
- Testing
- Ultrasound/transient elastography
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Retinopathy of Prematurity (ROP)
To Assess the Effect of Dexamethasone Eye Drops on the Retinopathy of Prematurity Outcome
The purpose is to compare the treatment frequency of preterm infants who developed severe Retinopathy of Prematurity (ROP) during the years 2015-2018 with 2020-2021 in the country, using the statistical method 'difference in…
- Trial name
- NCT06775353
- Testing
- Dexamethasone eyedrop
- Where
- Sweden
- Volunteers
- 2,017 people, healthy volunteers welcome
- Sponsor
- Region Skane
Treatment Outcome, Muscle Dystonia
Quantifying Muscle Tone in Patients With Brain Injury - a Feasibility Study
This project will determine the feasibility and validity of measuring elbow muscle flexor stiffness in a population of patients with sub-acute severe acquired brain injury using two measurement methods, the portable spasticity…
- Conditions
- Treatment Outcome, Muscle Dystonia, Spasticity, Muscle, Muscle Tightness
- Trial name
- NCT04207632
- Testing
- Botulinum toxin type A injection
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Autism Spectrum Disorders
Cortical Metrics Assessment Outcome Measure Development in Autism With Memantine Treatment
Specific Aim 1: Obtain proof of concept evidence that cortical metrics will change in response to treatment with Memantine extended release (XR)®, an agent that modulates n-methyl d-asptartate (NMDA) receptor activation, in…
- Trial name
- NCT02353130
- Testing
- Memantine-XR
- Sponsor
- University of North Carolina, Chapel Hill
COVID-19
Validation of Prognostic Clinical Risk Scores in Predicting Outcome for Patients With COVID-19 at Initial Triage
Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causing Covid-19 pandemic continues to be a global health threat with a massive burden on health care systems resulting in more than six million deaths in…
- Trial name
- NCT05582382
- Testing
- logistic regression of known prognostic markers of severity of COVID19
- Where
- United Arab Emirates
- Volunteers
- 2,000 people
- Sponsor
- Dr Adnan Agha
Atopic Dermatitis
Effect of vitk2 on Atopic Dermatitis Pediatrics Patients
investigate the effectiveness and safety of adding vitamin K2 at a dose of 45 mg/day for 12 weeks to conventional therapy for paediatric patients with moderate to severe atopic dermatitis according to SCORAD score
- Trial name
- NCT07574242
- Testing
- vit k2
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- October 6 University
Infant, Premature
The Edmonton Randomised Controlled Trial of NIDCAP - Based Developmental Care
NIDCAP based developmental care is a method of looking after preterm infants that is guided by the infant's behavioural cues, and that actively involves parents in the care of their infant.
- Trial name
- NIDCAP (NCT00552383)
- Testing
- NIDCAP based developmental care
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Alberta
Juvenile Idiopathic Arthritis, Oligoarthritis, Polyarticular Juvenile Rheumatoid Arthritis
Ultrasonography in Juvenile Idiopathic Arthritis
The purpose of this study is to analyse the usability of ultrasonography together with biomarkers in the investigation of patients diagnosed with juvenile idiopathic arthritis.
- Conditions
- Juvenile Idiopathic Arthritis, Oligoarthritis, Polyarticular Juvenile Rheumatoid Arthritis, Systemic Juvenile Idiopathic Arthritis
- Trial name
- NCT01304420
- Testing
- Ultrasonography
- Where
- Denmark
- Volunteers
- 95 people
- Sponsor
- University of Aarhus
Clubfoot
Pedobarographic Assessments of Clubfoot Treated Patients
The purpose of this study is to determine the utility of pedobarographs in evaluating clubfoot post-treatment.
- Trial name
- NCT00175708
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of British Columbia
Congenital Cystic Adenomatoid Malformation
Effects of Additional Fentanyl to Epidural Bupivacaine for Post-Thoracotomy Pain in Neonates
The study exams whether adding an opioid to the epidural infusion of a local anesthetic in neonates will significantly improve the quality of the postoperative analgesia.
- Trial name
- NCT00286143
- Testing
- Fentanyl
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Children's Hospital of Philadelphia
Microtia, Outcome Assessment
Safety and Efficacy of Connecting the Residual Ear to the Cartilage Scaffold in First- vs. Second-Stage Surgery
Eligible patients will be admitted from the outpatient clinic to complete the relevant examinations after admission（Preoperative routine examination and chest CT）.
- Conditions
- Microtia, Outcome Assessment, RCT, Surgery Related Complications Rate
- Trial name
- NCT06763991
- Testing
- Two-stage connection, One-stage connection
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Sichuan Provincial People's Hospital
B-Cell ALL, B-Cell Acute Lymphoblastic Leukaemia
A Multi-site Study to Evaluate the Persistence of Protective Immunity to Routine Childhood Vaccinations in Participants With B-ALL/Ly Who Have Received Blinatumomab
The goal of this observational study is to establish a clear vaccination protocol for pediatric patients (less than 21 years old) who have received treatment for B-cell Acute Lymphoblastic Leukemia/Lymphoma.
- Conditions
- B-Cell ALL, B-Cell Acute Lymphoblastic Leukaemia, B-Cell Lymphoblastic Leukemia, B-Cell Lymphoblastic Leukemia/Lymphoma
- Trial name
- BOOSTER (NCT07422337)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Breast Cancer, Radiomics
Radiomics of Mp-MRI Assessing NAC Outcome in Breast Cancer
This is a single-arm, multicentre study that aims to assess whether Radiomics combining multiparametric MRI and clinical data could be a good predictor of the responses to neoadjuvant chemotherapy in Breast Cancer.
- Conditions
- Breast Cancer, Radiomics, Neoadjuvant Chemotherapy, Multi-parametric MRI
- Trial name
- NCT03592004
- Testing
- neoadjuvant chemotherapy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese Academy of Sciences
Assess the Outcome for Children With Covid-19 Admitted in Assuit University Children Hospital
Pattern of Admission of Children With COVID-19 Admitted in Assuit University Children Hospital.
A novel coronavirus was identified following a cluster of cases of pneumonia in Wuhan, China, in December 2019. It rapidly spread as an outbreak there.
- Trial name
- NCT05940155
- Testing
- RT PCR test of COVID 19
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Spinal Cord Injuries
Caring for Caregivers: Supporting Caregivers of Youth With Spinal Cord Injury
The current study will implement and evaluate a multi-component, psychoeducational intervention for caregivers of children with spinal cord injury (SCI) ages 7-12. Two hypotheses will be tested.
- Trial name
- NCT02083601
- Testing
- Parent Forum, Psychological support
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Erin Hayes Kelly, PhD
NOMID, DIRA
Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID/CAPS, DIRA, CANDLE, SAVI, NLRC4-MAS, Still'S-like Diseases, and Other Undifferentiated Autoinflammatory Diseases)
Background: Some diseases cause chronic inflammation with intermittent flares in the body. These are called autoinflammatory diseases. They can cause fevers, rashes, ulcers, and other problems.
- Conditions
- NOMID, DIRA, NLRC4-MAS, SAVI
- Trial name
- NCT02974595
- Where
- United States
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Development
Neurodevelopmental Outcomes of Preterm Infants Treated for Pain Management With Repeated Doses of Sucrose 24%
The purpose of this study is to determine the effect of sucrose 24% for pain prevention on preterm infants. Our hypothesis is that repeated doses of sucrose 24%, given prior to painful procedure,do not impair neurodevelopmental…
- Trial name
- NCT01742520
- Testing
- multiple doses of sucrose, Formula or breast milk
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Gastroesophageal Reflux Disease (GERD), Erosive Esophagitis
Esomeprazole for Treatment of GERD in Pediatric Patients
To look at the safety and improvement in symptoms of a once a day dosing of esomeprazole in children 1 to 11 years old with inflammation of their esophagus or food pipe ("esophagitis") caused by gastroesophageal reflux disease…
- Conditions
- Gastroesophageal Reflux Disease (GERD), Erosive Esophagitis, Non-erosive Esophagitis
- Trial name
- NCT00228527
- Testing
- Esomeprazole (Nexium)
- Where
- 36 sites in United States, Belgium and 2 more
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
Class III Malocclusion, Maxillary Deficiency
Evaluation of Pain and Functional Impairments When Treating Class III Malocclusion Using Two Treatment Procedures
A clinical examination of each recalled candidate patient will be carried out at Adib Al Lahham Centre at the Ministry of Health Damascus to ensure that he/she meets the inclusion criteria.
- Trial name
- NCT06877780
- Testing
- RMR with SME, BAIMT with RME
- Where
- Syria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Damascus University
Degenerative Disc Disease, Degenerative Spondylolisthesis
Evaluation Of Spinelink® Fixation In The Treatment Of Degenerative Spondylolisthesis And Spinal Instability
The purpose of this open, multi-center study is to prospectively collect outcome data on patients who are having lumbar spinal fusion surgery with implantation of the SpineLink® system.
- Trial name
- NCT00726310
- Testing
- SpineLink® , SpineLink® II
- Where
- 2 sites in United States
- Volunteers
- 202 people
- Sponsor
- Zimmer Biomet