Clinical trials: Over Weight
Obesity, Exercise
Structured Exercise Prescription Program in Obese Children
This controlled clinical trial aims to compare the effects of a multicomponent program that includes structured personalized exercise prescription in children with obesity with a control group that will be enrolled in a…
- Conditions
- Obesity, Exercise, Cardiovascular Risk Factor, Liver Diseases
- Trial name
- NCT03552367
- Testing
- Personalized structured exercise program, Non personalized non-structured exercise program
- Where
- Mexico
- Volunteers
- 140 people
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Physical Activity, Adiposity
Effectiveness of a Physical Activity Intervention on Preventing Obesity During the Adiposity Rebound Period.
Coordinated project whose objectives are: a) to assess the effectiveness of a physical activity intervention (MOVI-KIDS) on preventing obesity and improving fitness during the adiposity rebound period; and b) to examine the…
- Conditions
- Physical Activity, Adiposity, Children, Obesity
- Trial name
- MOVI-KIDS (NCT01971840)
- Testing
- MOVI-KIDS
- Where
- Spain
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Prader-Willi Syndrome, Obesity
Double-Blind, Placebo Controlled, Phase 3 Trial of ZGN-440 (Beloranib) in Obese Subjects With Prader-Willi Syndrome
The purpose of this study is to evaluate efficacy and safety of ZGN-440 (beloranib) in obese adolescent and adult subjects with Prader-Willi Syndrome.
- Trial name
- bestPWS (NCT02179151)
- Testing
- ZGN-440 for Injectable Suspension
- Where
- 15 sites in United States
- Volunteers
- 108 people
- Sponsor
- Zafgen, Inc.
Over Weight, School Age Children
Structured Wii Aerobic Protocol on Reaction Time and Pulmonary Functions in Over Weight School- Aged Children
Childhood overweight have emerged as major global health concerns and are linked to lower pulmonary functions and reaction time levels among school-aged children.
- Trial name
- NCT07513298
- Testing
- The Nintendo Wii Fit operates on the Wii system, produced by Nintendo Co., Ltd, based in Kyoto, Japan., Chest physical therapy and diet therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Zaytoonah University of Jordan
PreDiabetes, Obesity
Clinical Trial of Crocus Kozanis Administration in Obese Children and Adolescents
The study aims to investigate possible effects of per os Crocus Kozanis administration in children and adolescents with obesity
- Conditions
- PreDiabetes, Obesity, Dyslipidemias
- Trial name
- NCT05572749
- Testing
- Crocus Kozanis, Metformin
- Where
- Greece
- Volunteers
- 75 people
- Sponsor
- Aristotle University Of Thessaloniki
Beta-thalassemia Major, Sickle Cell Disease
Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload
Interventional Allocation: Randomized Endpoint Classification: Safety/Efficacy Study of combined chelation therapy Masking: Open Label Primary Purpose: Treatment of transfusional iron overload Primary Outcome Measures: The…
- Conditions
- Beta-thalassemia Major, Sickle Cell Disease, Iron Hemosiderosis
- Trial name
- NCT01511848
- Testing
- DFP (ferriprox) and deferasirox (ICL 670), DFP, DFO
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Obesity, Over-weight
An Efficacy, Safety, and Pharmacokinetics Study of Beloranib in Obese Subjects With Prader-Willi Syndrome
The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics for certain doses of beloranib in obese subjects with Prader-Willi Syndrome.
- Conditions
- Obesity, Over-weight, Prader-Willi Syndrome
- Trial name
- NCT01818921
- Testing
- ZGN-440 sterile diluent, 1.2 mg ZGN-440 for injectable suspension, 1.8 mg ZGN-440 for injectable suspension
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Zafgen, Inc.
Overweight and Obesity
Young, Fit and Happy. A Web-based Intervention to Prevent Obesity in Adolescents.
The prevalence of overweight and obesity is increasing throughout the world. Obesity is seen as one of the most important public health threats because of the significant impact of chronic conditions associated with obesity.
- Trial name
- YFH (NCT01700309)
- Testing
- Young and Active
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Oslo Metropolitan University
Anorexia Nervosa, Bulimia Nervosa
Development of Gastrointestinal Symptoms in Patients With Anorexia Nervosa and Bulimia Nervosa During Weight Rehabilitation Over Time, Depending on the Nutritional Strategy
This prospective observational study investigates the development of gastrointestinal (GI) symptoms in patients with anorexia nervosa (AN) and bulimia nervosa (BN) during multi-week inpatient weight rehabilitation.
- Trial name
- GastroRehab (NCT07112014)
- Where
- Germany
- Volunteers
- 185 people
- Sponsor
- University Hospital Tuebingen
Human African Trypanosomiasis (HAT)
Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal Study
The aim of the study is to assess the efficacy and safety of an oral regimen of fexinidazole (once daily for 10 days) in the treatment of stage 1 and stage 2 T.b.
- Trial name
- NCT02184689
- Testing
- fexinidazole
- Where
- Democratic Republic of the Congo
- Volunteers
- 125 people
- Sponsor
- Drugs for Neglected Diseases
Knee Osteoarthrosis
Conservative Management vs. Arthroplasty in Knee Osteoarthritis
The goal of this observational study is to learn about the long-term effects of a non-surgical management programme in people with osteoarthritis that are eligible for a knee joint replacement surgery to treat their knee…
- Trial name
- NCT06623149
- Testing
- Non-Surgical Intervention, Current practice
- Where
- 6 sites in Denmark
- Volunteers
- 2,500 people
- Sponsor
- Marius Henriksen
Overweight, Obesity
Body Weight Assessment in Swiss Primary School Children: Trend Analysis Over 10 Years
Background: Recent evidence from several countries has emerged suggesting that the increase in the prevalence of childhood obesity has slowed down substantially, or even leveled off.
- Trial name
- NCT01572935
- Where
- Switzerland
- Volunteers
- 2,979 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Obesity & Overweight
OBE2026 - Effect of One Year Intensive Lifestyle Treatment in Children With ISO-BMI Over 30kg/m² and Their Families.
Obesity has increased significantly in recent decades and is starting earlier than before, even before school age. In 2023, 8% of Finnish boys aged 7-12 and 4% of girls were obese, while the corresponding figures for boys aged…
- Trial name
- NCT07738029
- Testing
- Lifestyle Management
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Tampere University Hospital
Pregnancy, Obesity
Investigation of Continuous Versus Interrupted Subcutaneous Fat Closure in Reducing Surgical Site Infection
This research aims to clarify the best way to perform subcutaneous tissue closure in overweight and obese patients undergoing caesarean section to reduce the occurrence of surgical site infections.
- Trial name
- NCT05856968
- Testing
- continuous subcutaneous tissue closure, Interrupted subcutaneous tissue closure
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Polycystic Ovary Syndrome (PCOS) Women, Obesity
Semaglutide in Women With Polycystic Ovary Syndrome and Obesity
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder that is frequently associated with metabolic features, including obesity.
- Trial name
- NCT06896981
- Testing
- Metformin with Semaglutide
- Where
- Bangladesh
- Volunteers
- 31 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Healthy Infants
A Phase III Study to Assess the Immunogenicity and Safety of Eutravac (DTap-HB Combined Vaccine) With DTaP and Hepatitis B Vaccines in Healthy Infants
To evaluate and compare the immunogenicity of Eutravac (Diphtheria-Tetanus-acellular Pertussis [DTaP] Hepatitis B [HB] combined) vaccine with separate but simultaneous administrations of DTaP and HB vaccine each administered to…
- Trial name
- NCT01896739
- Testing
- Eutravac
- Where
- 7 sites in South Korea
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Overweight, Hyperlipidemia
Cross-Over Multicentre Study in Adolescents
The main objective of this study is to evaluate the effects of two diets with different glycemic index and fibre content on glucose metabolism and plasma lipid profile of 80 adolescents in 4 European centres.
- Trial name
- HELENA-COMS (NCT00635544)
- Testing
- dietary treatment
- Where
- 4 sites in Greece, Hungary and 2 more
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federico II University
Weight Change, Body
Weight Change in PWS Over Six Months
This is a completely text-messaging based study and all data will be collected via surveys administered on a mobile phone. For this study, we will gather and analyze data on changes in body weight over a 6-month interval in…
- Trial name
- NCT03585244
- Testing
- weekly weight
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Foundation for Prader-Willi Research
Adiposity, Insulin Sensitivity
The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)
This is an 8 to14-week three-arm randomized controlled in children 8 to 12 years old. The main purpose of the study is to evaluate if stevia has benefits for weight control and metabolic function relative to caloric sweeteners…
- Conditions
- Adiposity, Insulin Sensitivity, Weight Gain, Blood Pressure
- Trial name
- NCT05992688
- Testing
- Sucrose sweetened beverage, Stevia sweetened beverages, Calorie free flavored water beverage
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Overweight, Obese
Ideas Moving Parents and Adolescents to Change Together (IMPACT)
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institute of Health (NIH) has sponsored a consortium of four sites across the United States, entitled Childhood Obesity Prevention and Treatment Research…
- Trial name
- IMPACT (NCT01514279)
- Testing
- HealthyCHANGE, SystemCHANGE
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Case Western Reserve University