Clinical trials: Overactive Bladder
Normal Pressure Hydrocephalus
Effect of Depletive Lumbar Puncture on Lower Urinary Tract Dysfunction in iNPH
Lower urinary tract dysfunction in normal pressure hydrocephalus has received little attention from the scientific community. Urinary symptoms in normal pressure hydrocephalus are mainly represented by overactive bladder, which…
- Trial name
- PLHPN (NCT03877107)
- Testing
- Urinary symptoms profile questionnaire, Micturition calendar
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- EssaiClinique_PL-HPN
Bladder Dysfunction
NESA Neuromodulation Versus Transcutaneous Posterior Tibial Stimulation
Introduction: Overactive bladder (OAB) is a common condition characterized by urinary urgency, frequency, and, in some cases, urge incontinence.
- Trial name
- NesaTibial (NCT07019597)
- Testing
- Non-invasive neuromodulation NESA(NNG), Non-invasive Neuromodulation Posterior Tibial (NTPG)
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Daniel David Álamo Arce
Myelomeningocele, Bladder, Neurogenic
Effect of Botulinum Toxin in Neurogenic Bladders in Children With Myelomeningocele
The purpose of this study is to examine how injection of botulinum toxin in the bladder affects bladder function. The trial is carried out in children born with malformation of the spinal cord and subsequent overactive bladders.
- Trial name
- NCT00175123
- Testing
- Botulinum A toxin
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Overactive Bladder
The Efficacy of Botulinum Toxin in OVERACTIVE Bladder
To assess the efficacy of botulinum toxin injection in overactive bladder.
- Trial name
- NCT03888001
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Overactive Bladder
Cardiovascular Morbidity During Treatment of Overactive Bladder With B3 Agonists
Overactive bladder syndrome complicates life for many women. 60-70% of women report improvement with treatment but the antikolinergic treatment is often limited by the adverse events, for example dry mouth, obstipation and…
- Trial name
- NCT02622555
- Testing
- Mirabegron
- Where
- Sweden
- Volunteers
- 221 people
- Sponsor
- Karolinska Institutet
Overactive Bladder Syndrome
TTNS Versus Sham Therapy for Children With iOAB (TaPaS Part I)
Part I of the TaPaS trial forms part of a twofold clinical RCT: Part 1) A prospective RCT comparing the efficacy of transcutaneous tibial nerve stimulation (TTNS) with TTNS sham therapy for children with idiopathic overactive…
- Trial name
- TaPaS (NCT04256876)
- Testing
- TTNS
- Where
- Belgium
- Volunteers
- 6 people
- Sponsor
- University Hospital, Ghent
Urinary Incontinence, Urinary Bladder
OnabotulinumtoxinA for the Treatment of Urinary Incontinence Due to Overactive Bladder in Pediatric Patients (12 to 17)
This was a multicenter, randomized, double-blind, parallel-group, multiple-dose study to evaluate the efficacy and safety of BOTOX in adolescents with urinary incontinence due to overactive bladder (OAB) with inadequate…
- Conditions
- Urinary Incontinence, Urinary Bladder, Overactive
- Trial name
- NCT02097121
- Testing
- BOTOX®
- Where
- 39 sites in United States, Australia and 11 more
- Volunteers
- 56 people
- Sponsor
- Allergan
Urinary Bladder, Overactive
A Study to Investigate How Effective and Safe Solifenacin Succinate Suspension is in Treating Children/Adolescents Aged 5 to Less Than 18 Years With Symptoms of Overactive Bladder (OAB) Compared to a Non-active Drug
Solifenacin succinate as a tablet formulation is already on the market for the treatment of symptoms of overactive bladder in adults.
- Trial name
- LION (NCT01565707)
- Testing
- Solifenacin Succinate Suspension, Urotherapy
- Where
- 46 sites in United States, Belgium and 14 more
- Volunteers
- 189 people
- Sponsor
- Astellas Pharma Europe B.V.
Voiding Disorders, Overactive Bladder
Beta 3 Agonists in Treatment of Non-neurogenic Voiding Dysfunction in Children
A randomized clinical study to evaluate the safety and efficacy of using the Beta 3 agonist drug (Mirabegron) combined with standard behavioral therapy in comparison to using the anticholinergic drug (Solifenacin) combined with…
- Trial name
- NCT05240456
- Testing
- Beta3-Agonists, Adrenergic, Anticholinergic drug, Solifenacin
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Overactive Bladder
Educating Patients on Management of Overactive Bladder: Written Versus Verbal Instructions
Background: Overactive bladder (OAB) is a common condition among postmenopausal women, requiring a multifaceted treatment approach that requires patient retention of information given to them in clinic.
- Trial name
- NCT02197533
- Testing
- Written List
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Overactive Bladder
Efficacy and Safety of High Dose Vitamin D Supplementation for Overactive Bladder Dry in Children
This prospective, randomized, 3-arms, parallel-design, controlled clinical trial is conducted to determine whether high dose vitamin D supplementation (combined with standard urotherapy ) improves outcomes, compared with…
- Trial name
- NCT05709990
- Testing
- Solifenacin Succinate 5 MG Oral Tablet [Vesicare], Vitamin D3, Standard urotherapy
- Where
- China
- Volunteers
- 303 people
- Sponsor
- Xing Liu
Urinary Bladder, Overactive, Overactive Bladder
Vitamin D Treat-to-Target Strategy for Children With Overactive Bladder-Wet
The purpose of this clinical trial is to investigate whether adding high-dose vitamin D (2,400 IU daily) to standard medical treatment (solifenacin combined with behavioral therapy) is more effective than standard treatment alone…
- Conditions
- Urinary Bladder, Overactive, Overactive Bladder, Urinary Incontinence, Urge
- Trial name
- NCT06201013
- Testing
- urotherapy, Solifenacin Succinate, Vitamin D3
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Overactive Bladder, Voiding Disorders
Feasibility of Parasacral Transcutaneous Electrical Nerve Stimulation PTENS for Voiding Dysfunction in Peds Population
Pilot study for determining feasibility of home parasacral transcutaneous electrical nerve stimulation in treatment of urinary urgency and incontinence.
- Conditions
- Overactive Bladder, Voiding Disorders, Incontinence, Urinary
- Trial name
- NCT04570605
- Testing
- parasacral transcutaneous electrical nerve stimulation (PTENS), Standard Urotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Idiopathic Overactive Bladder Resistant to Anticholinergic Treatment
Efficacy of 200 IU OnabotulinumtoxinA in Idiopathic Overactive Bladder Resistant to Anticholinergic Treatment
This study aimed to assess the efficacy and safety of onabotulinumtoxinA (botulinum toxin type A) in patients with idiopathic overactive bladder (OAB) and urinary incontinence who had previously failed to respond to…
- Trial name
- NCT06408051
- Testing
- Injection of onabotulinumtoxinA into the bladder wall
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Urinary Incontinence in Children
Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)
The primary objective is to evaluate if (1) combination therapy of solifenacin and mirabegron in low doses is superior to monotherapy of solifenacin in high dose and if (2) combination therapy of mirabegron and solifenacin in low…
- Trial name
- NCT06551246
- Testing
- Solifenacin, Mirabegron
- Where
- 5 sites in Denmark
- Volunteers
- 236 people
- Sponsor
- University of Aarhus
Overactive Bladder
Acupuncture Combined With Mirabegron in the Treatment of OAB
Introduction: As conventional treatments for overactive bladder (OAB) have not yet shown satisfactory results, new approaches are needed.
- Trial name
- ACWMITTOOAB (NCT06181019)
- Testing
- 50 mg of mirabegron, acupuncture combined with mirabegron.
- Where
- China
- Volunteers
- 75 people
- Sponsor
- The Affiliated Ganzhou Hospital of Nanchang University
Overactive Bladder
Drug Use-Results Survey of Betanis Tablets in Japan
This study is to determine the following information. 1. The occurrence of adverse drug reactions in clinical settings. 2. Factors potentially impacting safety, effectiveness, and other aspects.
- Trial name
- NCT01919047
- Testing
- Betanis
- Where
- 8 sites in Japan
- Volunteers
- 10,711 people
- Sponsor
- Astellas Pharma Inc
Urinary Bladder, Overactive
Single-dose Study to Assess Pharmacokinetics of Solifenacin Succinate Suspension in Children and Adolescents
This single-dose study will investigate how well solifenacin suspension is taken up, how long it stays in the body and how well it will be tolerated in children and adolescents aged 5-17 years with symptoms of overactive bladder.
- Trial name
- NCT01262391
- Testing
- Solifenacin succinate suspension 2.5 mg, Solifenacin succinate suspension 5 mg, Solifenacin succinate suspension 10 mg
- Where
- 8 sites in Belgium, Denmark and 2 more
- Volunteers
- 42 people
- Sponsor
- Astellas Pharma Inc
Overactive Bladder
Comparison of Caffeine Reduction and Anticholinergic Medications for Treatment of Overactive Bladder
The purpose of this study is to assess the effects of caffeine reduction/elimination on urinary symptoms in women with overactive bladders and compare this therapeutic approach to anticholinergic therapy.
- Trial name
- NCT00780832
- Testing
- Dietary Caffeine reduction, Anticholinergic medication
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- IWK Health Centre
Overactive Bladder
Efficacy of Darifenacin and Physiotherapy for the Treatment of Overactive Bladder in Women
Overactive bladder is a common problem among adult women. Darifenacin is an antimuscarinic drug that is frequently used as part of the management of the condition. However, current evidence backing its use is limited.
- Trial name
- NCT02143570
- Testing
- Darifenacin, Physiotherapy
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Universidad de Valparaiso