Clinical trials: Overeating
Feeding and Eating Disorders, Anorexia Nervosa
Efficacy of Juniver, a Digital Self-help Intervention, on Symptoms of Eating Disorders: A Randomised Controlled Trial
This project aims to assess the efficacy of the Juniver program on symptoms of eating disorders via a randomised controlled trial.
- Conditions
- Feeding and Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- NCT06226233
- Testing
- Juniver program
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- King's College London
Genomic and Metabolomic Variations, Preterm Birth
Effects of Genomic and Metabolomic Variations of Choline on Risk of Preterm Birth and Clinical Outcomes in Preterms
The incidence of preterm birth increases annually. Premature delivery has become the leading cause of neonatal illness and death.
- Conditions
- Genomic and Metabolomic Variations, Preterm Birth, Total Parenteral Nutrition
- Trial name
- NCT02841813
- Testing
- No intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Bardet Biedl Syndrome (BBS), Bardet Biedl Syndrome
Real-World Effects of MC4R Agonist Therapy in BBS and Severe Genetic Obesity
Bardet-Biedl syndrome (BBS) and other rare disorders associated with impairment of the melanocortin-4 receptor (MC4R) pathway are characterized by severe early-onset obesity, hyperphagia, and substantial morbidity.
- Conditions
- Bardet Biedl Syndrome (BBS), Bardet Biedl Syndrome, Bardet-Biedl Syndrome (BBS), Alstrom Syndrome
- Trial name
- REAL-MC4 (NCT07674290)
- Testing
- Setmelanotide
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Tom Hühne
Anorexia Nervosa, Bulimia Nervosa
The Effects of Written Emotional Disclosure on Eating Disorder Pathology in a Clinical Eating Disordered Population
A technique that has been found to be effective at relieving the physical and psychological symptoms associated with inhibiting emotions and emotional thoughts is written emotional disclosure.
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Eating Disorder
- Trial name
- NCT00766558
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Milton S. Hershey Medical Center
Prematurity, Neonatal Screening
Amino Acid and Acylcarnitine Profiles in Premature Neonates
Primary Hypotheses of the study include: Metabolic profiles are influenced by gestational age, chronological age, type and degree of nutritional support and illness Metabolic profiles differ between neonates who receive…
- Conditions
- Prematurity, Neonatal Screening, Parenteral Nutrition
- Trial name
- NCT00865150
- Where
- 2 sites in United States
- Volunteers
- 1,003 people, healthy volunteers welcome
- Sponsor
- Pediatrix
Overweight and Obesity, Pediatric Obesity
Evaluating the Feasibility of a Stepped-care Approach to Treating Adolescents With Binge and Loss of Control Eating
There are limited evidence-based treatments for adolescents with binge eating and fewer specifically targeting adolescents with both binge eating and overweight/obesity.
- Conditions
- Overweight and Obesity, Pediatric Obesity, Eating, Binge
- Trial name
- NCT03404713
- Testing
- Pathways to Health, Be4U
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Virginia Commonwealth University
Prader-Willi Syndrome, Hyperphagia
Fiber Intervention on Gut Microbiota in Children With Prader-Willi Syndrome
Prader-Willi syndrome (PWS) is the most common syndromic cause of obesity. Individuals with PWS characteristically experience excessive weight gain and severe hyperphagia with food compulsivity in early childhood, which often…
- Trial name
- NCT04150991
- Testing
- Fiber intervention
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Alberta
Eating Disorders
An fMRI Study of Self-regulation in Adolescents With Bulimia Nervosa
The aim of this project is to use both multimodal MRI and behavioral measures to investigate how changes in frontostriatal neural systems contribute to the development and persistence of Bulimia Nervosa (BN).
- Trial name
- NCT00345943
- Testing
- MRI, Neuropsychological Testing
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Metabolic Bone Disease
Markers of Bone Disease in Children on Parenteral Nutrition
Parenteral nutrition (PN) is the provision of nutrients via the intravenous route. Parenteral nutrition associated metabolic bone disease (MBD) was first described in children in the 1980s.
- Trial name
- NCT01603472
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Bulimia Nervosa
Family Therapy for Adolescent Bulimia Nervosa
The primary hypotheses are: A procedurally distinct family therapy is an effective and essential way to reduce bingeing and purging in adolescents with BN, and leads to the long-term amelioration of bulimic symptoms.
- Trial name
- NCT00518843
- Testing
- FBT-BN, SPT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Chicago
Cholestasis
Low Dose Fat for the Prevention of Liver Disease in Babies With Gastrointestinal Disorders
Neonates with congenital/acquired gastrointestinal disorders are at high risk for Parenteral Nutrition Associated Cholestasis (PNAC).
- Trial name
- NCT01373918
- Testing
- Intralipid
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- University of California, Los Angeles
Eating Disorders in Adolescence, Eating Disorders
Animal-Assisted Therapy in Adolescents With Eating Disorders
This study aims to improve eating disorders symptomatology, mental, psychosocial and physical health, quality of life, strength and body composition of adolescents with eating disorders by the development of a dog-assisted…
- Conditions
- Eating Disorders in Adolescence, Eating Disorders, Anorexia Nervosa/Bulimia
- Trial name
- NCT04869423
- Testing
- Dog-Assisted Therapy
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Daniel Collado-Mateo
Aluminum Contamination of Parenteral Nutrition
Serum Aluminum Concentration of Pediatric Patients Receiving Long-Term Parenteral Nutrition
The purpose of this study is to determine whether children on long-term parenteral nutrition (>6 weeks) have serum aluminum concentrations that are higher than children (aged and gender matched) that have never received…
- Trial name
- NCT01371123
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Hyperphagia, Prader-Willi Syndrome
ARD-101 for Treatment of PWS: The Hunger Elimination or Reduction Objective Trial
The goal of this clinical trial is to learn if ARD-101 works to treat hyperphagia-related behavior in patients with Prader-Willi syndrome (PWS). It will also teach us about the safety of ARD-101.
- Trial name
- HERO (NCT06828861)
- Testing
- ARD-101
- Where
- 31 sites in United States, Australia and 3 more
- Volunteers
- 68 people
- Sponsor
- Aardvark Therapeutics, Inc.
CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection
Neonatal Catheter Lock for Infection Prevention
For newborns admitted to Neonatal Intensive Care Units (NICUs), one of the main risk factors for late-onset sepsis is the presence of a central venous catheter (CVC), which is often essential for the administration of medications…
- Conditions
- CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection, Neonatal Sepsis, Late-Onset
- Trial name
- Neo-CLIP (NCT07585188)
- Testing
- Taurolidine 2% lock, Normal saline lock
- Where
- Italy
- Volunteers
- 576 people
- Sponsor
- University of Turin, Italy
Bardet-Biedl Syndrome, POMC Deficiency
Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Participants With Specific Gene Defects in the MC4R Pathway
A trial to compare the weekly and daily formulations of setmelanotide in participants with genetic defects in the melanocortin-4 receptor pathway.
- Trial name
- NCT05194124
- Testing
- Setmelanotide 2 mg, Setmelanotide 2.5 mg, Setmelanotide 3 mg
- Where
- 7 sites in United States, Canada and 4 more
- Volunteers
- 19 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Obesity, Overweight
Preventing Excessive Weight Gain in Adolescent Girls at High-Risk for Adult Obesity
This study will examine whether interpersonal psychotherapy (IPT) can help reduce excessive weight gain in adolescent girls. It will compare the effectiveness of IPT with a teen health education program in preventing weight gain.
- Conditions
- Obesity, Overweight, Binge Eating
- Trial name
- NCT00680979
- Testing
- Interpersonal Psychotherapy, Health Education
- Where
- 2 sites in United States
- Volunteers
- 166 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Obesity, Eating Disorders
Internet Weight Control for Bingeing Adolescents
The purpose of this study is to determine if an internet-based intervention designed to reduce binge eating and improve healthy weight regulation skills will result in reductions in binge eating and weight loss, or weight…
- Trial name
- NCT00125112
- Testing
- Internet-based intervention designed to reduce binge eating and improve healthy weight regulation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pediatric Obesity, Inhibition
Brain Mechanisms of Overeating in Children
The proposed research will follow healthy weight children who vary by family risk for obesity to identify the neurobiological and appetitive traits that are implicated in overeating and weight gain during the critical…
- Conditions
- Pediatric Obesity, Inhibition, Decision Making, fMRI
- Trial name
- RO1 (NCT03341247)
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Penn State University
Binge Eating, Purging (Eating Disorders)
Emotion Regulation in Binge Eating and Purging Among Adolescents
The study will examine the neural and behavioral correlates of emotion regulation in adolescents engaging in binge eating and/or purging and healthy adolescents.
- Trial name
- NCT03429114
- Testing
- Magnetic resonance imaging
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Stanford University