Clinical trials: Overweight and/or Obesity
Obesity, Childhood, Pediatric Obesity
Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers
The US Preventive Services Task Force (USPSTF) recommends that providers screen children aged 6 years and older for obesity and offer or refer them to a comprehensive behavioral intervention (≥26 hours over a period of up to 12…
- Conditions
- Obesity, Childhood, Pediatric Obesity, Childhood Obesity, Adolescent Obesity
- Trial name
- TEAM UP (NCT03843424)
- Testing
- eSOC program, FBT program
- Where
- 7 sites in United States
- Volunteers
- 1,460 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Childhood Overweight and Obesity Immersive Physical Activity
Immersive Physical Activity Program for Overweight Schoolchildren
Childhood overweight and obesity are major public health concerns associated with increased cardiometabolic risk and reduced quality of life.
- Trial name
- PEESO (NCT07681856)
- Testing
- RVI_Experimental_Immersive Virtual Reality Exergame Program, RVI_ControGroup_Immersive Virtual Reality Exergame Program
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- University of Vigo
Diet Habit
Family and Web-based Nutrition Intervention to Increase Vegetable, Fruit, and Dairy Intakes in Children
Considering the high prevalence of childhood obesity worldwide, effective interventions are needed . Parental involvement in interventions and the use of web-based modalities appear to be promising approaches.
- Trial name
- NCT03798808
- Testing
- Consumption of fruits, vegetables and dairy products
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Laval University
Type 2 Diabetes
Middle-School Based Primary Prevention Trial of Type 2 Diabetes
HEALTHY was a primary prevention trial conducted in 42 middle schools at 7 locations across the US to impact risk factors for type 2 diabetes in adolescents.
- Trial name
- HEALTHY (NCT00458029)
- Testing
- integrated program of nutrition, activity, behavior, and promotion
- Where
- 8 sites in United States
- Volunteers
- 4,603 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Adiposity, Insulin Resistance
PREterM FOrmula Or Donor Breast Milk for Premature Babies
In order to address this crucial question, central to preterm newborn care, a multicentre United Kingdom (UK) -wide study randomising 4000 preterm babies would be necessary to achieve sufficient power to evaluate the impact on…
- Conditions
- Adiposity, Insulin Resistance, Metabolomic Profile, microRNA Profile
- Trial name
- PREMFOOD (NCT01686477)
- Testing
- Unfortified Human donor Milk used to make up any shortfall in mother's own milk, Fortified Human donor Milk used to make up any shortfall in mother's own milk, Preterm Formula used when there is a shortfall in mother's own milk
- Where
- United Kingdom
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity & Overweight, Weight Loss
Sustaining Health After an Intensive Weight-loss Pro-gramme
Since 2021 Copenhagen University Hospital - Hvidovre, Denmark, has offered a 2-year, highly specialised, intensive clinical weight loss programme to patients living with severe and complex obesity, who due to somatic and/or…
- Conditions
- Obesity & Overweight, Weight Loss, Weight Management in Adult Patients With Obesity or Overweight
- Trial name
- SHAPe (NCT07900178)
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Pediatric Obesity
Efficacy of a School-based Obesity Prevention Program in Mexican Schoolchildren: Cluster Randomized Controlled Trial
There is evidence that obesity prevention programs show positive effects on obesity and lifestyle parameters. However, the effect of the programs delivered by different implementers is unknown, and in Mexico, the available…
- Trial name
- NCT05461703
- Testing
- Planet Nutrition Program
- Where
- Mexico
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
Metabolic Disease, Obesity
Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
Background: Researchers are interested in studying individuals who have known or suspected metabolic, inflammatory or genetic diseases that may put them at a high risk for heart diseases or diseases of their blood vessels.
- Conditions
- Metabolic Disease, Obesity, Li-Fraumeni Syndrome, Cardiomyopathy
- Trial name
- NCT01143454
- Testing
- NSR IDE-MRI: Research pulse sequences
- Where
- 3 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Type 2 Diabetes
Strength Training and Nutrition Development for African American Youth
The investigators are conducting an intervention study to examine the effects of a 16-week exercise and diet interventions on prevention of disease, specifically type 2 diabetes and heart disease, in African American youth.
- Conditions
- Obesity, Type 2 Diabetes, Cardiovascular Risk, Cancer
- Trial name
- STAND (NCT01441323)
- Testing
- Nutrition, Strength Training & Nutrition
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Pediatric Obesity
Pediatric Quality of Life Among Population With Body Mass Index (BMI) Greater Than or Equal to 85%
We are currently experiencing an epidemic of obesity in the Pediatric Population. This epidemic affects many areas including quality of life. We have been conducting a nutrition and exercise program since 2003.
- Trial name
- NCT00714870
- Testing
- Behavioral nutrition and exercise program
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Chronic Disease, Adolescent Asthma
Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being
The goal of this pilot clinical trial is to learn if a community referral program can improve services for youth with mental health and chronic health conditions in a predominantly Native Hawaiian and Pacific Islander community.
- Conditions
- Chronic Disease, Adolescent Asthma, Obesity & Overweight, Youth Mental Health
- Trial name
- Kamaehu (NCT07536256)
- Testing
- Community Referral to Kaiona Programs
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Waianae Coast Comprehensive Health Center
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Pregnancy, Obesity
Investigation of Continuous Versus Interrupted Subcutaneous Fat Closure in Reducing Surgical Site Infection
This research aims to clarify the best way to perform subcutaneous tissue closure in overweight and obese patients undergoing caesarean section to reduce the occurrence of surgical site infections.
- Trial name
- NCT05856968
- Testing
- continuous subcutaneous tissue closure, Interrupted subcutaneous tissue closure
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Obesity
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
This study has 2 parts: First part is the main study and second part is the extension study. During the main study participants will receive 1 of 4 study medicines.
- Trial name
- REDEFINE 1 (NCT05567796)
- Testing
- Cagrilintide, Semaglutide
- Where
- 256 sites in United States, Argentina and 21 more
- Volunteers
- 3,400 people
- Sponsor
- Novo Nordisk A/S
Overweight and/or Obesity, Children - Malnutrition
Family-Based Nutrition Intervention to Prevent Overweight and Obesity in School-Age Children.
This proposal aims to enhance the well being of schoolchildren and their families through a mobile application and multidisciplinary intervention model grounded in authoritative parenting principles and social cognitive theory.
- Conditions
- Overweight and/or Obesity, Children - Malnutrition, Preventing Malnutrition
- Trial name
- NCT07159971
- Testing
- School B, Control
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Claudia Teresa Tovar Palacio
Metabolism Disorder, Insulin Sensitivity
Supervised Exercise-training in Children With Insulin Resistance or Healthy Metabolic Profile
Despite exercise training decrease blood fasting glycemia in 'average' terms, there is a wide interindividual variability after exercise training explored mainly in adults but not in children.
- Conditions
- Metabolism Disorder, Insulin Sensitivity, Obesity, Pediatric
- Trial name
- NCT03003754
- Testing
- High Intensity Training (HIT) + Resistance Training (RT), Control group
- Where
- Colombia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas
Overweight, Obesity
Evaluation of a Family Intervention Program for the Management of Overweight or Obese Children
Objectives: To evaluate the effectiveness of the Nereu program compared to standard care (advice on increased physical activity and nutrition) such as a health intervention tool for the childhood obesity management…
- Conditions
- Overweight, Obesity, Children
- Trial name
- NEREU (NCT01878994)
- Testing
- Counselling group, Nereu group
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Obesity
Obesity Guidelines for Outpatient Surgery
The investigators are concerned about anesthetizing obese children in outpatient locations in case they need prolonged stay, increased respiratory interventions, or need for post-operative narcotics.
- Trial name
- NCT01655238
- Testing
- BMI
- Where
- United States
- Volunteers
- 1,327 people
- Sponsor
- Nationwide Children's Hospital
Overweight and/or Obesity
Brief Inhibitory Training for Eating - Intervention
The purpose of this study is to conduct a proof-of-concept intervention of daily inhibitory control (IC) training. Aim 1 is to examine the feasibility, acceptability, and barriers of an IC training EMI in adolescents' daily life.
- Trial name
- BITE-I (NCT07592728)
- Testing
- Daily inhibitory control training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- George Mason University
Obesity
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
This study will look at how well semaglutide helps children and teenagers losing weight. This will be tested by comparing the effect on body weight in children and teenagers taking semaglutide in comparison to placebo, a "dummy"…
- Trial name
- STEP Young (NCT05726227)
- Testing
- Semaglutide
- Where
- 56 sites in United States, Austria and 8 more
- Volunteers
- 212 people
- Sponsor
- Novo Nordisk A/S