Clinical trials: PAD
Cardiovascular Diseases, Peripheral Vascular Diseases
Etiology and Prevalence of Peripheral Arterial Disease
To determine the prevalence of peripheral arterial disease in a defined population by non-invasive techniques; to evaluate the association of cardiovascular disease risk factors with peripheral vascular disease; to determine…
- Conditions
- Cardiovascular Diseases, Peripheral Vascular Diseases, Arterial Occlusive Diseases
- Trial name
- NCT00005142
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Buccal Fat Pad, Cleft Palate
Evaluating Salivary α - Amylase Levels Following Trigona Sp Honey Application To Post Palatoplasty Patients: A Pilot Randomized Clinical Study
Palatoplasty is a surgical procedure performed to restore palatal continuity and improve velopharyngeal function in patients with cleft palate.
- Conditions
- Buccal Fat Pad, Cleft Palate, Honey, Salivary Alpha Amylase
- Trial name
- NCT07610993
- Testing
- Trigona sp honey with the buccal fat pad technique, framicetyn sulfate dressing with the buccal fat pad technique, Trigona sp. honey dressing without the buccal fat pad technique
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Hasanuddin University
Peripheral Artery Disease
Genetics of Peripheral Artery Genomics
Peripheral artery disease is a disease that contributes to significant morbidity and mortality of millions of Americans yearly. Very little is known about the pathophysiology of atherosclerosis in peripheral artery disease.
- Trial name
- NCT00615121
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Duke University
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Critical Limb Ischemia
Study to Explore the Effect of Lowering Blood Viscosity in Patients With Treatment-resistant Critical Limb Ischemia
PAD is caused by an increased flow resistance in atherosclerotic ischemic limbs. The investigators hypothesize that reducing blood viscosity (through controlled phlebotomy), thereby increasing the deformability of red blood…
- Trial name
- CLI-PH (NCT01758874)
- Testing
- phlebotomy
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul Veterans Hospital
Peripheral Arterial Disease
Outcomes of Endovascular Treatment of Superficial Femoral Artery In-stent Restenosis
Lower limb peripheral arterial disease (PAD) is a common, important manifestation of systemic atherosclerosis. Stenosis or occlusions in the superficial femoral artery (SFA) may result in intermittent claudication or even…
- Trial name
- NCT04123639
- Testing
- PTA
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intermittent Claudication
Cross-sectoral Rehabilitation for Patients With Intermittent Claudication
Exercise training combined with other lifestyle changes are essential elements in conservative management of patients with Intermittent Claudication (IC).
- Trial name
- NCT03730623
- Testing
- Supervised exercise training
- Where
- Denmark
- Volunteers
- 118 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Limping
High Resolution IR Imaging for Diagnosis in the Acute Limping Child - ThermLimp
A variety of different diseases may cause a limp in a child, and in younger children it is particularly challenging to isolate the area affected.
- Trial name
- Thermlimp (NCT03312348)
- Testing
- Infrared imaging
- Volunteers
- 30 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Critical Limb Ischemia, Peripheral Arterial Occlusive Disease
Cryoplasty CLIMB-registry
In 5 Belgian hospitals, the data of 100 CLI-patients receiving the cryoplasty technique to treat their infrapopliteal arterial lesions will be collected.
- Trial name
- CLIMB (NCT00459888)
- Testing
- PolarCath Peripheral Dilatation System (Boston Scientific)
- Where
- 4 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Flanders Medical Research Program
Intermittent Claudication
(Cost) Effectiveness Study of Exercise Therapy in Patients With Peripheral Arterial Disease
The purpose of this study is to determine if supervised exercise therapy in a physiotherapeutic setting, with or without therapy feedback, is more (cost-)effective than exercise therapy based on a 'go home and walk' advice…
- Trial name
- EXITPAD (NCT00279994)
- Testing
- Exercise therapy, Accelerometer (PAM; Personal Activity Monitor), Oral Exercise Therapy advise
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Atrium Medical Center
Postoperative Hemorrhage
Neptune Pad ® Compared to Conventional Manual Compression
BACKGROUND. Arterial access site complications remain the most frequent adverse events after percutaneous transluminal procedures.
- Trial name
- NCT00597363
- Testing
- Neptune P.A.D. (R), conventional manual compression
- Where
- Austria
- Volunteers
- 201 people
- Sponsor
- Vienna General Hospital
Peripheral Artery Disease
Implementation of Vascular Care Team to Improve Medical Management of PAD Patients
This study intends to evaluate the efficacy of a multidisciplinary vascular care team utilizing an intensive guideline-based lipid reduction program in improving risk factor modification as measured by LDL-C reduction at 12…
- Trial name
- NCT04400409
- Testing
- Intervention A - Vascular Care + site 6MWT administration, Intervention B - Standard Care + site 6MWT administration, Intervention A - Vascular Care + CPC EQuIP 6MWT administration
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Colorado Prevention Center
Peripheral Arterial Disease
Exercise on Expression of Heat Shock Protein 70 in Arterial Risk
Introduction: Atherosclerotic Peripheral Arterial Disease (PAD) is the leading cause of mortality in the western world. To maintain homeostasis of the vessel wall, vascular cells produce a high level of heat shock proteins (HSP)…
- Trial name
- HSP70 (NCT04743128)
- Testing
- Exercise
- Where
- Mexico
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad Popular Autónoma del Estado de Puebla
Peripheral Arterial Diseases
Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone
The goal of this clinical trial is to learn if the Auryon Atherectomy System with balloon angioplasty safe and effective in treating lower limb blockages.
- Trial name
- AMBITION BTK (NCT06777901)
- Testing
- Auryon Atherectomy System, Balloon Angioplasty
- Where
- 9 sites in United States
- Volunteers
- 224 people
- Sponsor
- Angiodynamics, Inc.
Peripheral Vascular Diseases
A Non-Randomized Study of the NightHawk Peripheral Plaque Excision System During Plaque Excision of Peripheral Arterial Disease
To assess the proximity of the catheter to the vessel wall and to correlate excised tissue with images collected by the integrated Optical coherence Tomography (OCT) imaging system.
- Trial name
- NightHawk (NCT00516308)
- Testing
- NightHawk
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- FoxHollow Technologies
Infection
Do Fair Comparisons or Harms Data Increase Responsiveness to Feedback About Antibiotic Prescribing: 2x2 Factorial Trial
Antibiotic overuse is common and antibiotic prescribing contributes to rising rates of antimicrobial resistance. Primary care physicians prescribe the majority of all antibiotics and there is large inter-physician variability in…
- Trial name
- NCT04594200
- Testing
- Audit and Feedback (A&F)
- Where
- Canada
- Volunteers
- 5,107 people
- Sponsor
- Women's College Hospital
Back Pain, Back Disorder
Clinical Trial of Dvectis Pads in Comparison to no Pad Use in Patients With Chronic Lumbar Spine Pain
1. Introduction 1.1 Description of the Trial The trial was a monocentric, open, randomized, 3-arm clinical trial that took place at the Department of Orthopaedics of the Karviná Miners' Hospital (Karvinská hornická nemocnice…
- Conditions
- Back Pain, Back Disorder, Disease Lumbar Spine
- Trial name
- NCT03947580
- Testing
- Use of the Dvectis Single pad, Use of the Dvectis Double pad, Use of no pad
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- DD-Hippero s.r.o.
Peripheral Artery Disease, Coronary Disease
Evaluation of Patients With Known or Suspected Heart Disease
In this study researchers will admit and evaluate patients with known or suspected heart disease referred to the Cardiology Branch of the National Heart, Lung, and Blood Institute (NHLBI).
- Conditions
- Peripheral Artery Disease, Coronary Disease, Diabetes and Heart Failure, Dilated Cardiomyopathy
- Trial name
- NCT00001313
- Where
- 2 sites in United States
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cushing Syndrome
Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome
This is an open-label extension study to evaluate the long-term safety of relacorilant in patients with endogenous Cushing syndrome who successfully completed participation in a Corcept-sponsored study of relacorilant and may…
- Trial name
- NCT03604198
- Testing
- relacorilant
- Where
- 48 sites in United States, Austria and 8 more
- Volunteers
- 125 people
- Sponsor
- Corcept Therapeutics
Peripheral Artery Disease
Oxygen-guided Supervised Exercise Therapy
Peripheral artery disease (PAD) is a cardiovascular disease manifesting from systemic atherosclerosis, which blocks the leg arteries and results in insufficient blood flow to the lower extremities.
- Trial name
- MOMET (NCT06003855)
- Testing
- Supervised exercise therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- VA Office of Research and Development