Clinical trials: PCOS
PCOS Disease
Studying the Starvation Effect on Androgen Metabolism in 20 Healthy Young Women and Comparison to Women With PCOS.
In this study, the investigators wanted to investigate the energy homeostasis and the steroid metabolism of 20 healthy, young and normal weight women aged between 16-35 years before and after a 48 hours fasting period.
- Trial name
- SEA (NCT03573063)
- Testing
- Androgen metabolism after starvation
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
PCOS, Myo-inositol-resistance
Myo-inositol Plus Alpha-lactalbumin in PCOS Myo-inositol-resistant Patients
The investigator's aim is to evaluate if the combination of myo-inositol and alpha-lactalbumin can overcome the resistance to myo-inositol in PCOS patients
- Trial name
- NCT03667443
- Testing
- Myo-inositol + folic a. + α-lactalbumin, Myo-inositol + folic a.
- Where
- Bulgaria
- Volunteers
- 50 people
- Sponsor
- Lo.Li.Pharma s.r.l
Polycystic Ovary Syndrome, Insulin Resistance
The Role of Insulin Resistance in PCOS
Polycystic ovary syndrome (PCOS) phenotype can be structured into three components: anovulation, hyperandrogenism and the metabolic syndrome (of which hyperinsulinemia, secondary to insulin resistance, is the central…
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Obesity
- Trial name
- NCT00173043
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Polycystic Ovary Syndrome
The Secretion of Incretin Hormones in Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is an endocrine disease in reproductive women. It is characterized by anovulation and hyperandrogenism.
- Trial name
- NCT02126592
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Periodontitis, Polycystic Ovary Syndrome
Evaluation of Periodontal Status and hsCRP Levels in Females With PCOS on CPA/EE Combination Drug Regimen
PCOS is a widely reported condition among young female population and anti-androgen agents are increasingly being used as part of the medical management of such cases.
- Conditions
- Periodontitis, Polycystic Ovary Syndrome, Gingivitis
- Trial name
- NCT05021861
- Testing
- Cyproterone Acetate, Ethinyl Estradiol Drug Combination, FEMALE PATIENTS WITH PCOS, Control group
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
PCOS
Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents
To exam in the effect of a combination of low dose Metformin and Spironolactone on functional brain MRI, menstrual regulation and metabolism in adolescents with PCOS.
- Trial name
- NCT03981861
- Testing
- Metformin and Spironolactone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Children's Mercy Hospital Kansas City
Polycystic Ovary Syndrome
Coenzyme Q10 and Clomiphene Citrate (CC) for Ovulation Induction in Polycystic Ovary Syndrome
Objective of the study was to evaluate the effect of combination of oral Coenzyme Q10 (CoQ10), with clomiphene citrate (CC) for ovulation induction in CC-resistant polycystic ovary syndrome (PCOS).In a prospective controlled…
- Trial name
- NCT01910766
- Testing
- Coenzyme Q10, clomiphene citrate
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Polycystic Ovary Syndrome
The Use Of AMH for the Discrimination of Polycystic and Multicystic Ovaries in Nonhyperandrogenic Patients
AMH is a member of the transforming growth factor family. It is produced by the granulosa cells from 36th weeks of pregnancy.Ovarian granulosa cells are the only source of the antimüllerian hormone.
- Trial name
- NCT01878955
- Testing
- AMH level difference between patient with PCOS and multicystic ovaries.
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
PCOS
Role of Myo-inositol and D-chiro Inositol on the Ovaric and Metabolic Functions
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age and is characterized by menstrual abnormalities, clinical or biochemical hyperandrogenism, multiple abnormal cysts and…
- Trial name
- NCT01626443
- Testing
- Myo-inositol + D-chiro-inositol + Folic acid, Folic acid
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Lo.Li.Pharma s.r.l
Polycystic Ovary Syndrome
Ovarian Hyperandrogenism in Normal and Excessive Body Weight Adolescent Girls and Their Relation to Diet (HAstudy)
The objective was 1. to check whether serum androgen levels and concomitant metabolic changes, oxidative stress and inflammation in adolescent girls with hyperandrogenism may be related to diet. 2.
- Trial name
- NCT04738409
- Testing
- Lifestyle intervention, Effects of AIDiet intervention to improve diet quality, immuno-metabolic health in normal and overweight PCOS girls
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Poznan University of Physical Education
Polycystic Ovary Syndrome (PCOS), Obesity &Amp;Amp; Overweight
Strengthening Healthy Emotional Co-regulation of Mothers With PCOS and Obesity and Their Infants
It is both timely and important to invest in interventions that can improve healthy emotional co-regulation. It is proposed to evaluate the feasibility and limited efficacy of an adapted, brief, multimodal intervention: ECoFam…
- Trial name
- ECoFam (NCT07129434)
- Testing
- ECoFam
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Oulu University Hospital
Interpersonal Psychotherapy, Polycystic Ovary Syndrome
Interpersonal Psychotherapy in Adolescents With Polycystic Ovary Syndrome
The main purpose of this study is to find out whether taking part in a group-based interpersonal psychotherapy (IPT) program designed to improve mood and lessen stress in girls with PCOS will improve depression, unhealthy eating…
- Trial name
- IPAP (NCT06056453)
- Testing
- Interpersonal Psychotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
PCOS
Comparison of Myoinositol and Metformin in PCO
Aim of the study is to compare the effect of myoinositol and metformin in the resumption of the spontaneous menstrual cycle in patients diagnosed with PCOS or having oligo/amenorrhea, reduction in weight and BMI, Improvement in…
- Trial name
- PCO (NCT04204044)
- Testing
- Metformin Hydrochloride, Myo-inositol
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Rashid Latif Medical College
Polycystic Ovary Syndrome
Markers and Calculation of Cardiovascular Risk in the Distinct Phenotypes of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder and cause of anovulatory infertility among reproductive aged women.
- Trial name
- NCT01392781
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Secondary Dysmenorrhea, Dysmenorrhea
Iyengar Yoga Therapy for Dysmenorrhea and Endometriosis
The purpose of this clinical trial is to look at the effectiveness of prescribing yoga classes to patients with dysmenorrhea (irregular or painful periods), or other menstrual disorders on patients' self reported pain and quality…
- Conditions
- Secondary Dysmenorrhea, Dysmenorrhea, Dysmenorrhea Secondary, Polycystic Ovary Syndrome
- Trial name
- NCT03784976
- Testing
- Iyengar Yoga Therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Illinois at Urbana-Champaign
Polycystic Ovary Syndrome, PCOS
Obstetric Outcomes in Women With PCOS
The aim of the study is to investigate body composition in newborn children of women with PCOS and controls and to investigate adverse obstetric outcomes in pregnant women with PCOS.
- Trial name
- NCT01983202
- Where
- Denmark
- Volunteers
- 1,248 people
- Sponsor
- Odense University Hospital
PCOS
Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS
The investigators aim to conduct a double blind randomized clinical trial to study the independent and additive effects of micronutrients (Resveratrol, Acetyl-L Carnitine, L Arginine and COQ10 ) with Metformin in patients with…
- Trial name
- NCT05653895
- Testing
- Resveratrol, Metformin, Acetyl-L-Carnitin, L Arginine, Co-Q10
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Khyber Medical University Peshawar
Polycystic Ovary Syndrome
Insulin Resistance, Polycystic Ovary Syndrome, and Bone Research Study
The purpose is to investigate the effects of 2 different treatments (drospirenone/ethinyl estradiol versus rosiglitazone) on insulin sensitivity and androgen levels, inflammatory markers, vascular markers and bone development in…
- Trial name
- NCT00640224
- Testing
- rosiglitazone, drospirenone/ethinyl estradiol
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Silva Arslanian
Controlled Ovarian Hyperstimulation, Polycystic Ovarian Syndrome
Progesterone Primed Ovarian Stimulation Versus GnRH Antagonist Protocols in Women With Polycystic Ovarian Syndrome
The purpose of this study is to compare the use of the progesterone-primed ovarian stimulation protocol versus GnRH antagonist protocol in women with polycystic ovarian syndrome (PCOS) regarding the number of oocytes retrieved…
- Trial name
- NCT06812559
- Testing
- Progesterone, GnRH antagonist (Cetrorelix)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- El Shatby University Hospital for Obstetrics and Gynecology
Study the Relationship Between Insulin Resistance With Hormonal and Ovarian Morphological Characteristics in Patients With Polycystic Ovarian Syndrome
Correlation of Insulin Resistance With Hormonal and Ovarian Morphological Characteristics in Patients With Polycystic Ovarian Syndrome
We designed a study to determine if ovarian volume (OV) and/or follicle number (FN) are independently associated with abnormal metabolic findings in women diagnosed with PCOS.
- Trial name
- NCT05661565
- Testing
- No intervention
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University