Clinical trials: PDD
Autism Spectrum Disorder
Translating Neuroprediction Into Precision Medicine Via Brain Priming
The present study examines the impact of oxytocin (OXT) and Pivotal Response Treatment (PRT) on the development of language, social, and play skills in young children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT03370510
- Testing
- Oxytocin, Pivotal Response Treatment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Biliary Tract Cancer
Varlitinib in Combination With Gemcitabine and Cisplatin for Treatment naïve Advanced or Metastatic BTC
The study intends to evaluate the following objectives in patients with advanced or metastatic biliary tract cancer who have not received systemic therapy for advanced/metastatic disease.
- Trial name
- NCT02992340
- Testing
- Varlitinib, Cisplatin, Gemcitabine
- Where
- 3 sites in Singapore, South Korea and 1 more
- Volunteers
- 204 people
- Sponsor
- ASLAN Pharmaceuticals
Anxiety
Effect of a Social Script iPAD Application for Children With Autism Spectrum Disorder
The purpose of the research is to test the effectiveness of the social story intervention delivered using the iPAD application "Going to Imaging" on the anxiety, challenging child behaviors, child injuries and completion rates…
- Trial name
- NCT01655485
- Testing
- Patient teaching
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Autism Spectrum Disorder
How Simplified Language Affects Comprehension and Learning in Young Autistic Children
The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with ASD.
- Trial name
- PALS (NCT05707923)
- Testing
- Linguistic simplification
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Michigan State University
Endometrial Cancer
Combination Chemotherapy Compared With Hormone Therapy in Treating Patients With Recurrent, Stage III, or Stage IV Endometrial Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Estrogen can stimulate the growth of tumor cells.
- Trial name
- NCT00016341
- Testing
- filgrastim, cisplatin, doxorubicin hydrochloride
- Where
- 50 sites in United States, Canada
- Sponsor
- Gynecologic Oncology Group
Autism Spectrum Disorders
Sensory Supported Swimming for Children With ASD
The purpose of Sensory Supported Swimming is to provide a sustainable, low cost recreational swim program for children with ASD.
- Trial name
- SSS (NCT02747459)
- Testing
- Sensory Supported Swimming
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- University of Kansas Medical Center
Autism Spectrum Disorder (ASD
Effectiveness of Clown Therapy in Facilitating Dental Visits for Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in verbal and non-verbal communication and social interaction, as well as repetitive and stereotyped behaviors.
- Trial name
- NCT07906288
- Testing
- Familiarization sessions using clown therapy, Familiarization sessions with conventional methods
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- University of Milan
Anxiety, Autism Spectrum Disorder
Buspirone for Anxiety in Autistic Youth
The purpose of the study is to do a preliminary trial to determine if buspirone is effective, safe, and tolerable in autistic youth with anxiety.
- Trial name
- NCT07439042
- Testing
- buspirone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Cervical Cancer
Gemcitabine and Cisplatin in Treating Patients With Refractory or Recurrent Cancer of the Cervix
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00006482
- Testing
- cisplatin, gemcitabine hydrochloride
- Where
- 34 sites in United States, Canada
- Sponsor
- Gynecologic Oncology Group
Mental Health Wellness 1, Parent-Child Relations
BRIGHT Coaching Program for Families
Children with, or at elevated risk for, brain-based developmental disabilities can experience lifelong consequences and challenges throughout their development.
- Conditions
- Mental Health Wellness 1, Parent-Child Relations, Child Developmental Delay, Parenting
- Trial name
- NCT03880383
- Testing
- Coaching, Online parent education, Online peer support
- Where
- 4 sites in Canada
- Volunteers
- 306 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cervical Cancer, Endometrial Cancer
Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs, such as amifostine, may protect normal cells from the side effects of chemotherapy.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Neurotoxicity
- Trial name
- NCT00003624
- Testing
- amifostine trihydrate, cisplatin, paclitaxel
- Where
- 8 sites in United States
- Sponsor
- Gynecologic Oncology Group
Evaluation of Bian Stone Therapy for Autism Spectrum Disorder
Evaluation of the Effectiveness of Bian-Stone Therapy in Children With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a pervasive developmental disorder of brain abnormalities. It presents with difficulties of communication and social interaction, and restrictive interests and restrictive behaviors.
- Trial name
- NCT06998459
- Testing
- Bian-Stone therapy, Maintain the original treatment approach
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- Taichung Tzu Chi Hospital
Autism Spectrum Disorder
Precision TMS Treatment Guided by Personalized Brain Functional Sectors (pBFS) for ASD
This study will evaluate the efficacy and safety of pBFS-guided TMS treatment for the core symptom in autism spectrum disorder children, adolescents and young adults.
- Trial name
- NCT05890846
- Testing
- active iTBS, traditional 1on1 course
- Where
- 2 sites in China
- Volunteers
- 66 people
- Sponsor
- Changping Laboratory
Autism Spectrum Disorder, Attention Deficit-Hyperactivity Disorder
Community Based Intervention for Children With ADHD and ASD
The purpose of this study is to determine whether a new treatment, Unstuck and On Target (UOT), works better, worse, or the same as the best treatment that is available now, Contingency Behavioral Management (CBM), for low income…
- Conditions
- Autism Spectrum Disorder, Attention Deficit-Hyperactivity Disorder, Executive Function
- Trial name
- NCT03003286
- Testing
- Unstuck and on Target (UOT), Parents and Teachers Supporting Students (PATSS)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Lauren Kenworthy
ADHD, Conduct
Variance of Video Games Playing Patterns Among Adolescents With Psychiatric Disorders
As the use of video games (VG) is rapidly increasing, many studies have tries to understand the effects of VG on the children and adolescents playing them.
- Conditions
- ADHD, Conduct, Depression, Anxiety
- Trial name
- NCT01621815
- Testing
- Video Game
- Where
- Israel
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Autism Spectrum Disorder
Emergent Multi-Class Imitation Training
The goals of this project are to (a) incorporate empirical findings on imitation training and learning in autistic children into a comprehensive protocol for Applied Behavior Analysis practitioners designed to rapidly facilitate…
- Trial name
- EMIT (NCT05849376)
- Testing
- Emergent Multi-Class Imitation Training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
Autism Spectrum Disorder
Integrating the ESDM in ASD Preschools in Israel
The current study evaluates the effectiveness of the Early Start Denver Model (ESDM) when integrated in existing community preschools for children with ASD.
- Trial name
- ESDM-ISR (NCT03362840)
- Testing
- Early Start Denver Model, Eclectic preschool intervention
- Where
- Israel
- Volunteers
- 59 people
- Sponsor
- Bar-Ilan University, Israel
Osteosarcoma, Survival
Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma
Treatment strategies for high-grade osteosarcoma with multidrug chemotherapy and resection result in 3-year event-free survival of 60-70%.
- Conditions
- Osteosarcoma, Survival, Chemotherapy Effect, Toxicity, Drug
- Trial name
- MAPAC (NCT04351308)
- Testing
- MAPI chemotherapy, Apatinib Mesylate, Camrelizumab
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University People's Hospital
Autism Spectrum Disorder
Paediatric Autism Communication Therapy (PACT) in Children With Autism Spectrum Disorder
Paediatric Autism Communication Therapy (PACT) is a naturalistic developmental behavioural interventions to reduce autism symptoms.
- Trial name
- DAN-PACT (NCT05673096)
- Testing
- PACT, MAU
- Where
- 6 sites in Denmark
- Volunteers
- 280 people
- Sponsor
- University of Southern Denmark
Sarcoma
Chemotherapy in Treating Patients With Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00014313
- Testing
- cisplatin, etoposide
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
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