Clinical trials: PERIODONTAL DISEASE
Periodontal Diseases, Peri-implantitis
Implant Surface Decontamination With 2 % Chlorhexidine in Peri-implantitis Treatment
Peri-implantitis is a infectious disease that resides in the mucosa surrounding dental implants and also affects the supporting bone.
- Trial name
- NCT01852253
- Testing
- 2% chlorhexidine, 0.12% chlorhexidine
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- University Medical Center Groningen
Gingival Recession
Topical Phenytoin for Management of Gingival Recession
Gingival recession (GR) is a term that describes the displacement of the gingival margin apical to the cemento-enamel junction (CEJ) of a tooth.
- Trial name
- NCT07590375
- Testing
- phenytoin cream
- Volunteers
- 30 people
- Sponsor
- Cairo University
Pulpitis - Irreversible, Apical Periodontitis
Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments
With consideration of the previous studies regarding the properties of i-PRF, it will be used in combination with another bioactive material: (Nano-BAG) versus using of i-PRF only as a pulpotomy material with using a premixed…
- Trial name
- NCT05902936
- Testing
- Pulpotomy for mature permanent mandibular molars
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis
Comparative Evaluation of Chlorhexidine, Metronidazole and Combination Gels on Gingivitis
Patient presenting to the dental clinic with gingivitis and fulfilling the inclusion criteria will be included in the study after taking informed consent. Participants will be divided into three groups.
- Trial name
- NCT03142607
- Testing
- Metronidazole gel, Chlorhexidine Gluconate
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Gingival Recession
Effect of Suturing Protocols on Coronally Advanced Flap for Root Coverage Outcomes
The purpose of this retrospective study is to investigate whether suturing protocols (suture removal timing) influence root coverage outcomes in recession defects treated with a coronally advanced flap (CAF) procedure.
- Trial name
- NCT05472233
- Testing
- Suture removal after Coronally Positioned Flap
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Oral Health, Oral Hygiene
Effectiveness of Personalized Oral Hygiene Education in Medical and Dental Students Over Two Years
This prospective cohort study is designed to evaluate the long-term effects of individualized oral hygiene education, known as Individually Trained Oral Prophylaxis (iTOP), on oral health outcomes in medical and dental students…
- Conditions
- Oral Health, Oral Hygiene, Periodontal Health, Dental Plaque
- Trial name
- iTOP (NCT07085013)
- Testing
- Individually Trained Oral Prophylaxis (iTOP)
- Where
- Bosnia and Herzegovina
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Mostar
Periodontal Disease, Periodontal Bone Loss
Laser Assisted Open Flap Debridement
The study involves the surgical treatment of patients with Stage I to III of periodontitis. Following completion of Steps 1 and 2 of periodontal therapy according to the EFP guidelines for the treatment of periodontitis, sites…
- Trial name
- LaserOpen (NCT07807215)
- Testing
- Mechanical Open Flap debridement, Laser assisted open flap debridement
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Dental Implantation, Peri-implant Mucositis
Evaluation of Peri-implant Conditions of Orthodontic Mini Implants
This observational study aims to evaluate the peri-implant conditions of mini implants placed during orthodontic treatment. Orthodontic mini implants are commonly used as temporary anchorage devices to prevent or reduce unwanted…
- Conditions
- Dental Implantation, Peri-implant Mucositis, Gingival Inflammation, Implant Stability
- Trial name
- NCT06491849
- Testing
- Peri-implant Condition Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Mehmet Selim Yildiz
Peri-Implantitis
Effect of a Maintenance Protocol After Surgical Treatment of Peri-implantitis
This study was designed as a 12-month, two arms, randomized clinical trial to evaluate the efficacy of a supportive treatment protocol (SPIT).
- Trial name
- NCT05574218
- Testing
- Glycine air powder, Rubber cup polishing
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Dental Plaque, Saliva Altered
Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables
The purpose of this study is to determine the effect of three times a day mastication, during a follow-up period of 4 weeks, of two sugar-substituted chewing gums on various factors associated with dental caries and gingivitis.
- Conditions
- Dental Plaque, Saliva Altered, Gingivitis
- Trial name
- NCT01578603
- Testing
- xylitol, casein phosphopeptide amorphous calcium phosphate complex
- Where
- Colombia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Pediatric Obesity, Pediatric Dentistry
Oral Health in Children and Adolescents With Obesity and Normal Weight
We aimed to compare the oral health status (dmft/DMFT index, IDCAS-II, BEWE, plaque index, gingival index, probing depth) between normal-weight (NW) and obese (OW) children/adolescents.
- Trial name
- NCT06283602
- Testing
- oral health status
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Peri-implant Mucositis, Peri-Implantitis
Metabolomic and Proteomic Fingerprinting in Peri-implant Diseases
Due to the limited efficacy of its treatment modalities, there is a stringent need to improve the prevention and early diagnosis of peri-implantitis.
- Trial name
- NCT04283903
- Testing
- PICF
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidad Complutense de Madrid
Periodontal Diseases
Interactive School-Based Oral Health Education Program to Reduce Periodontal Disease in Palestinian Adolescents
The goal of this intervention study was to evaluate the effectiveness of a two-month interactive school-based oral health education program in reducing periodontal disease and improving oral health behaviors among 15-year-old…
- Trial name
- ISBOHE-PD (NCT07055932)
- Testing
- "Interactive Oral Health Education Program"
- Where
- Palestinian Territories
- Volunteers
- 946 people, healthy volunteers welcome
- Sponsor
- Al-Quds University
Oral Health, Dental Caries
The Use of Artificial Intelligence in the Dental X-rays Analysis
This cross-sectional study aims to perform a population-based assessment of the incidence of decay, dental fillings, root canal fillings, endodontic lesions, implants, implant and dental abutment crowns, pontic crowns, and…
- Conditions
- Oral Health, Dental Caries, Periapical Diseases, Tooth Loss
- Trial name
- NCT06258798
- Testing
- Taking a dental X-ray
- Where
- Poland
- Volunteers
- 1,025 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
Dental Caries, Orphaned Children
Evaluation of Oral and Dental Health of Institutionalized Orphan Children Residing in Children's Homes in Turkey
Both dental caries prevalence and periodontal status of children residing in children's homes in Sivas province of Turkey were evaluated.
- Conditions
- Dental Caries, Orphaned Children, Periodontal Index
- Trial name
- NCT06725654
- Testing
- Diagnostic Procedures
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Apical Periodontitis
Effect of Coronal Extent of Obturation on Endo-perio Lesions
Increased incidence of apical periodontitis was reported where root filling was found coronal to the marginal bone due to communication between pulp and periodontal space.
- Trial name
- NCT03171376
- Testing
- Root canal treatment and coronal restoration
- Volunteers
- 60 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis, Tongue Coating
Effect of Periodontal Treatment on Tongue Coating and Smell Function
This study aims to investigate the effect of periodontal treatment on olfactory function in patients with periodontitis by comparing pre- and post-treatment periodontal indices, Winkel tongue coating scores, and Sniffin' Sticks…
- Conditions
- Periodontitis, Tongue Coating, Olfactory Dysfunction
- Trial name
- EPTOS (NCT07326319)
- Testing
- Non-Surgical Periodontal Treatment (Scaling and Root Planing
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Batman University
Bone Loss, Alveolar, Tooth Loss
Tooth Autotransplantation and Bone Dimension Changes
Tooth autotransplantation is a treatment option to replace tooth with imposible prognosis. In several cases the receipt site has a reduced bone dimension.
- Conditions
- Bone Loss, Alveolar, Tooth Loss, Bone Atrophy, Alveolar
- Trial name
- NCT03927937
- Testing
- AUTOTRANSPLANTATION TOOTH
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Endodontic-Periodontal Lesions, Apical Periodontitis
The Effect of Different Intra-canal Medications on Healing of Endo-perio Cases.
Assessment of different intra-canal medications in endo-perio lesion regarding their healing potentiality and their effect on local cytokine levels.
- Trial name
- NCT07858396
- Testing
- Bio-ceramic, Calcium Hydroxide (CH), Chlorhexidine
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Abdominal Aorta Aneurism, Periodontitis
Clinical and Microbiological Relationships Between Periodontitis and Abdominal Aorta Aneurism: an Case Control Study
Aorta Abdominal aneurism (AAA) is a chronic degenerative disorder leading to the dilation and eventually to the rupture of the aortic wall.
- Conditions
- Abdominal Aorta Aneurism, Periodontitis, Dentulous
- Trial name
- NCT03767023
- Testing
- cross sectional
- Volunteers
- 61 people
- Sponsor
- University of Liege