Clinical trials: PERIODONTAL DISEASE
Treatment, Periodontitis, Apical
Treatment of Young Permanent Teeth With Different Adjuvant Approaches
To determine microbiology assessment of infected root canal in young permanent teeth, as well as antimicrobial efficiency of different adjuvant treatment modalities including photodynamic therapy (PDT), high-power diode laser…
- Conditions
- Treatment, Periodontitis, Apical, Necrotic Pulp
- Trial name
- NCT05291195
- Testing
- Laser-device group, Essential Oil, Sodium hypochlorite group
- Where
- Serbia
- Volunteers
- 40 people
- Sponsor
- University of Belgrade
Odontogenic Cysts, Keratocysts of the Jaw
Decompression of Odontogenic Cysts
The aim of this case-control study is to evaluate the effects of decompression of cystic jaw lesions by means of comparing pre- and post-decompression histologic findings.
- Conditions
- Odontogenic Cysts, Keratocysts of the Jaw, Cysts Dental, Pathology
- Trial name
- NCT06536907
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Oral Hygiene, Orthodontics
Impacts of Oral Irrigation in Orthodontic Patients
The present study aimed to investigate clinically the cleaning effectiveness of different treatment modalities, that is, oral irrigator or interdental brush usage addition to routine brushing and examine interleukin (IL)-1β…
- Conditions
- Oral Hygiene, Orthodontics, Periodontal Diseases
- Trial name
- NCT05562986
- Testing
- GCF (gingival crevicular fluid) collection
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ondokuz Mayıs University
Periodontitis Stage II
"Comparison of Spirulina Gels for Treating Stage II Grade B Periodontitis"
This randomized controlled clinical study investigates the effectiveness of Spirulina gel and Spirulina nanoparticles gel in treating Stage II Grade B periodontitis.
- Trial name
- NCT06699654
- Testing
- Spirulina Gel, Spirulina Nanoparticles Gel
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Kafrelsheikh University
Periodontal Diseases
Tumor Necrosis Factor-alpha and Interleukin-18 Levels in Children With Gingivitis and Type 1 Diabetes Mellitus
This study aimed to evaluate the levels of interleukin 18 and tumor necrosis factor-alpha (TNF-α) in gingival crevicular fluid (GCF) of children with type 1 diabetes mellitus and gingivitis.
- Trial name
- NCT03910205
- Testing
- ELISA
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Alveolar Bone Loss
Use of Hyaluronic Acid as a Therapeutic Strategy for Bone Repair in Human
The aim of this study is to evaluate the effects of hyaluronic acid (HA) on bone healing in human dental sockets.
- Trial name
- NCT02709525
- Testing
- hyaluronic acid
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Periodontal Diseases, Periodontitis
Periodontal Status and Pregnancy or Delivery Complications in Type 1 Diabetes Mellitus Pregnant Women
The results of contemporary studies suggest an association between inflammatory periodontal disease and pregnancy and delivery complications.
- Conditions
- Periodontal Diseases, Periodontitis, Pregnancy Complications, Pregnancy in Diabetic
- Trial name
- NCT06002997
- Testing
- Pregnancy and/or delivery complications, Periodontal disease
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Dental Caries, Tooth Demineralization
Effectiveness of Two Health Education Interventions in the Prevention of Caries and Gingivitis in Orthodontic Patients
Dental caries and gingivitis are classified by the World Health Organization (WHO) as an important public health problem due to their high prevalence and incidence worldwide despite the development of public policies to combat…
- Conditions
- Dental Caries, Tooth Demineralization, Gingivitis
- Trial name
- NCT05979805
- Testing
- Conventional Educational interventions, Motivational intervention
- Where
- Colombia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Periodontitis
Running Title: PPAR-γ, RXR-α, and VDR Expressions in Periodontitis
Objective: The present study aimed to determine the expressions of nuclear receptors PPAR (Peroxisome proliferative activator receptor)-γ, RXR (Retinoid X receptor)-α, and vitamin D receptor (VDR) in healthy volunteers and…
- Trial name
- NCT04018144
- Testing
- Gingiva Biopsy Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Periodontal Disease
Influence of Periodontal Treatment During Pregnancy in Adverse Pregnant Outcomes
The aim of this study is to evaluate the effects of treatment of periodontal disease during the second trimester of gestation in adverse pregnancy outcomes.
- Trial name
- NCT00893802
- Testing
- Scaling and root planning
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Periodontitis
Hyaluronic Acid With Scaling & Root Planing In Chronic Periodontitis Patients With Diabetes Mellitus Type 2
The present study aimed to assess the adjunctive use of Hyaluronic acid with scaling \& root planing (SRP) in patients with chronic periodontitis \& diabetes mellitus type 2.
- Trial name
- NCT03807596
- Testing
- Periodontal treatment with Hyaluronic acid associated with SRP, Scaling & root planning alone
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Periodontitis and Pregnancy
L. Reuteri ATCC PTA 5289 + L. Reuteri DSM 17938 in Pregnant Women
Randomized controlled tril to evaluate the safety and efficacy for the combination of L. reuteri ATCC PTA 5289 \& L. reuteri DSM 17938 in pregnant women with periodontitis and/or gingivits to improve oral health and at the same…
- Trial name
- NCT03375125
- Testing
- Probiotic
- Where
- 2 sites in Italy, Mexico
- Volunteers
- 300 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
Apical Periodontitis
Assessment of Regenerative Potential of Mature Permanent Teeth With Necrotic Pulps Using Two Revascularization Protocols. (In Vivo Study)
Regenerative endodontic procedures have been used to successfully treat human mature permanent teeth with necrotic pulps and apical periodontitis.
- Trial name
- NCT04158232
- Testing
- Method
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minia University
Gingival Recession
Evaluation of SECTG Vs. Laser-DGG in Management of Gingival Recessions.
This study evaluates laser de-epithelialized gingival graft to be as effective as subepithelial connective tissue graft in management of multiple gingival recessions using tunneling technique.
- Trial name
- NCT04133298
- Testing
- Tunneling with laser de-epithelized gingival graft, Tunnelingwith subepithelial connective tissue graf
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Atrophy, Alveolar
Piezo-assisted Expansion of Narrow Ridges
the goal of the study was the evaluation of the clinical and histological performance of delayed inserted implants in augmented sites with a shaped solid graft inserted in an originally narrow alveolar edentulous ridge.
- Trial name
- PRIDE (NCT07401238)
- Testing
- Alveolar Ridge Reconstruction
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Periapical Periodontitis, Periapical Abscess
A Retrospective Cohort Study on the Non-Surgical Treatment of Periapical Inflammatory Lesions With Vitapex Paste
Background: Periapical inflammation is a common clinical condition, classified into periapical periodontitis, periapical granuloma, and periapical cyst.
- Conditions
- Periapical Periodontitis, Periapical Abscess, Periapical Radiolucency
- Trial name
- NCT07907367
- Testing
- Vitapex Paste
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Affiliated Hospital of Jinggangshan University
Apical Periodontitis
Accuracy of ERCLMDs in Teeth With Apical Periodontitis
The aim of this in vivo study is to evaluate the influence of apical periodontitis (AP) on the accuracy of Dentaport ZX, Raypex 5, and i-Root electronic root canal length measurement devices.
- Trial name
- ERCLMDs (NCT01904552)
- Testing
- Electronic Root Canal Length Measurement Device
- Where
- Iran
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Periodontitis (Stage 3)
Evaluation of The Periodontal Parameters Following Non-Surgical Periodontal Therapy With and Without Adjunctive Use of Injectable Platelet Rich Fibrin: A Randomized Controlled Clinical Trial
This randomized controlled clinical trial aims to evaluate the effectiveness of non-surgical periodontal therapy (NSPT) with and without the adjunctive use of injectable platelet-rich fibrin (I-PRF) in patients with chronic…
- Trial name
- NCT07090265
- Testing
- non-surgical periodontal therapy, non-surgical periodontal therapy + I-PRF
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes Mellitus, Poor Glycemic Control
Periodontal Care and Glycemic Control in Diabetes
Diabetes is a prevalent and costly disease among users of VA care. Goals of diabetes care include the prevention and/or delay of complications via adequate glycemic control.
- Conditions
- Diabetes Mellitus, Poor Glycemic Control, Peridontal Disease
- Trial name
- NCT00012688
- Testing
- Doxycycline HCI 10mg po for 2 weeks, Ultrasonic scaling with 0.12% chlorhexidine gluconate
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- US Department of Veterans Affairs
Periodontitis
Effect of Menstrual Cycle Phase on Pain Perception and Anxiety During Non-Surgical Periodontal Treatment
This study evaluates the effect of menstrual cycle phases on pain perception and dental anxiety during non-surgical periodontal therapy in premenopausal women with Stage II and III periodontitis.
- Trial name
- MAPP (NCT07719686)
- Testing
- Non Surgical Periodontal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Karadeniz Technical University