Clinical trials: PERIODONTAL DISEASE
Bone Atrophy, Alveolar
All-on-Four Implants With Ultrasonic
The objective of this observational study is the radiographic evaluation of marginal bone remodeling after surgical implant insertion in an immediate loading all-on-four technique with trans-sinusal titanium implants, correlating…
- Trial name
- Nobelsinus (NCT03357692)
- Testing
- all on four implant rehabilitation
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Gingival Hyperplasia, Dental Plaque
Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients
This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces.
- Conditions
- Gingival Hyperplasia, Dental Plaque, Tooth Demineralization
- Trial name
- NCT07115784
- Testing
- Chlorhexidine Varnish
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Apical Periodontitis
Clinical and Radiographic Success of Regeneration Using Injectable Platelet Rich Fibrin
Study aimed at assessing the clinical and radiographic success of pulp regeneration using injectable platelet-rich fibrin in mature permanent molars with apical periodontitis versus root canal treatment using Gutta Percha (GP)…
- Trial name
- NCT06086249
- Testing
- Regeneration using Injectable platelet-rich fibrin, Root canal treatment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Diseases
Coronally Advanced Flap With Two Different Techniques for the Treatment of Multiple Gingival Recessions
This study compared the clinical outcomes of coronally advanced flap using two different surgical strategies in the treatment of multiple gingival recessions.
- Trial name
- NCT02229669
- Testing
- Horizontal incisions, Oblique incisions
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Paulista University
Periodontal Bone Loss
Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients
The purpose of the study is to determine the effect of enamel matrix protein derivative on an inflamed, periodontal-involved tooth.
- Trial name
- NCT02972788
- Testing
- Enamel Matrix Proteins Derivative, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Dental Decay, Periodontal Abscess
ONE-1 Oral graNd Est 1
This study is about the assessment of two oral telemedecine tools compared to an intra oral clinical examination used as a reference among elderly persons living in nursing home.
- Conditions
- Dental Decay, Periodontal Abscess, Periodontitis, Gingivitis
- Trial name
- ONE (NCT05089214)
- Testing
- Intra oral cameras
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Apical Periodontitis
Comparison of Healing of Apical Periodontitis in Periodontally Diseased and Healthy Patients.
Periodontal health may jeopardize the success of endodontic treatment.Intraorifice barrier apart from enhancing probability of success of endodontic treatment may also augment periodontal therapy as intra pulpal infection is…
- Trial name
- NCT03711942
- Testing
- Intra orifice barrier, Base, Control
- Volunteers
- 90 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Diseases
Antimicrobial Photodynamic Therapy as an Adjunct Treatment for Periodontal Disease in Down's Syndrome Patients
The aim of this study was to evaluate the effectiveness of antimicrobial photodynamic therapy as an adjuvant of scaling and root planning for treatment of periodontal disease in patients with Down's Syndrome.
- Trial name
- NCT02938988
- Testing
- Antimicrobial photodynamic therapy, Scaling and root planning, red laser
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- University of Sao Paulo
Gingivitis
Clinical and Microbiological Effects of Lactobacillus Rhamnosus in Treatment of Gingivitis
The aim of this randomized placebo- controlled clinical trial is to evaluate the effects of Lactobacillus rhamnosus SP1- containing probiotic sachet as an adjunct to scaling and root planning (SRP).
- Trial name
- NCT02809313
- Testing
- Treatment Gingivitis with Probiotic, Treatment Gingivitis conventional
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Jorge Gamonal
Periodontal Diseases, Adverse Effects
Effect of Non-surgical Periodontal Treatment
Objective: The objective of this research was to compare the effect of a single session supragingival scaling in a group of pregnant women with periodontal disease with a group that received supra and subgingival scaling.
- Trial name
- EONSPT (NCT01533792)
- Testing
- Supra/subgingival scaling using periodontal curette scraping, Supra and subgingival scaling
- Volunteers
- 40 people
- Sponsor
- Universidade Federal do Maranhão
Gingivitis, Dental Plaque Accumulation
Study of an Essential Oil and a Delmopinol Mouthrinse Effect on Dental Plaque Accumulation Index, Gingivitis Index and on Streptococcus Mutans, Lactobacillus, Aerobic and Anaerobic Oral Bacteria Colony Counts.
The use of mouthrinses may be of relevance as a complement to daily dental hygiene procedures, especially for patients who do not comply with a proper mechanical removal of dental plaque.
- Trial name
- NCT01236950
- Testing
- Essential oils mouthrinse, Delmopinol mouthrinse
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Periodontitis
Efficacy of Curcumin Gel Combined With Non-surgical Periodontal Therapy on Salivary Procalcitonin Level in the Treatment of Periodontitis Patients
Objectives: To evaluate the efficacy of curcumin gel as an adjunct to scaling and root planing (SRP) on the salivary procalcitonin level in the treatment of periodontitis.
- Trial name
- NCT05667376
- Testing
- Local drug delivery, curcumin gel
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Reham abdelfatah
Periodontitis
Prevalence Of Periodontitis Stage III & IV
The study is a cross-sectional survey investigating the prevalence of Periodontitis stage III \& IV in Egyptian dental patients attending the oral diagnosis clinic at faculty of Dentistry, Cairo University
- Trial name
- NCT03779763
- Where
- Egypt
- Volunteers
- 750 people
- Sponsor
- Cairo University
Alzheimer Disease, Periodontitis
Periodonitis and Alzheimer's Disease
The main objective of this study is to assess whether Periodontal Disease is more prevalent in adult patients diagnosed with Alzheimer's Disease compared to adult patients without Alzheimer's Disease.
- Trial name
- NCT05189132
- Testing
- Periodontal Diagnosis, Microbiological analysis, Inflammatory mediators
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Health Behavior
Oral Health of Individuals Who Attended a Mother-child Dental Care Program - Longitudinal Study
The aim of this longitudinal study was to assess the oral health of individuals attending a mother-child dental care program (PPPWB).
- Trial name
- NCT01272544
- Volunteers
- 278 people
- Sponsor
- Universidade Federal do Piauí
Periapical Periodontitis
Single Versus Multiple Visits Endodontic Treatment
Healing rate after single visit or multiple visit endodontic treatment using triple paste intracanal medicament will be assessed both clinically and radio-graphically for follow-up period up to one year
- Trial name
- NCT02947763
- Testing
- mixture of metronidazole, ciprofloxacin, and minocycline
- Volunteers
- 44 people
- Sponsor
- Cairo University
Gingivitis
The Effects of Green Tea and Salvadora Persica L. in Patients With Gingivitis
Gingivitis is an inflammatory condition of the gingival tissue, most commonly caused by bacterial infection.The plaque control is considered the most important preventive factor concerning caries, gingivitis, and periodontitis…
- Trial name
- NCT06211309
- Testing
- co.mouthwas, Kin, Distilled water
- Where
- Iraq
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Alveolar Clefts, Alveolar Bone Grafting
Evaluation of Using Iliac Crest With and Without Platelet-Rich Fibrin in Repair of Congenital Alveolar Cleft
A randomized clinical trial aims to evaluate the clinical and radiographic outcomes of the repair of congenital alveolar clefts using Iliac crest graft with and without mixing with platelet-rich fibrin
- Conditions
- Alveolar Clefts, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- NCT06924216
- Testing
- alveolar bone grafting, alveolar bone grafting Plus Platelet rich fibrin
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Suez Canal University
Periodontal Health, Gingivitis
Effect of Probiotics on the Periodontal Status of Orthodontic Patients
Gingival inflammation (gingivitis) is commonly reported in teenagers with fixed orthodontic devices (FOD). Indeed, FODs promote the accumulation of plaque and interfere with the efficacy of tooth brushing.
- Trial name
- POP (NCT04634201)
- Testing
- Oral probiotics (L. reuteri)
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Lille
Chronic Periodontitis
The Response of Pathogens to the Respective or Combined Treatment of SRP and Local Minocycline in Chronic Periodontitis
To evaluate the respective or combinatory efficacy of locally delivered 2% Minocycline (MO) and surface and root planning (SRP) by assessing both clinical parameters and the loads of four main periodontal pathogens in treating…
- Trial name
- NCT02355977
- Testing
- minocycline, surface and root planning
- Volunteers
- 70 people
- Sponsor
- Zhejiang University